Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
7 Cards in this Set
- Front
- Back
|
def - Pathogenesis
|
mode of development of disease
|
|
|
def - Virulence
|
capacity to cause disease
|
|
|
def - Attenuation
|
loss of virulence
|
|
|
Disease Triad
|
1) pathogen or agent causing disease (virulence factors)
2) host 3) environment e.g. Hantavirus pulmonary syndrome |
|
|
What agent factors determine viral disease?
|
viral strain (virulence), route of infection, dose of virus
|
|
|
What host factors determine viral disease?
|
species, age, genetic susceptibility, immune status
|
|
|
Cell Tropism
|
1) spectrum of tissues/cells that may be infected by a virus
2) virus receptor (host cell protein) determine trophism 3) cell state (replication cycle is important in determining what kind of infection occurs |
