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59 Cards in this Set
- Front
- Back
-Host cell receptor: sialic acid
-Fusion protein -M-matrix protein |
Paramyxovirus
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HN attachment
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PARAINFLUENZA
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G attachment
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RSV
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Winter/rainy Season epidemics
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RSV
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Spring/Fall epidemics
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parainfluenza
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Neg ssRNA, 8 segments
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Influennza
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-M protein = membrane matrix protein
-Lipid memb: derived from host cell -Hemagluttinin and neuraminidase = what immunes sys recognizes |
Influenza
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Surface proteins VP1,2,3,4
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Entrvoirus
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VP1 = binding site for host receptors (hidden)
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Enteroviruses
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PrP
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Infectious proteins that lack nucleic acid or virus like structure
(prions) |
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structural HIV genes
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POL, GAG, ENV
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GP120
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BINDS W/ CD4 CELLS
ENVELOPE PROTEIN |
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GP 41
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ENVELOPE PROTEIN
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P24
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CAPSULE PROTEIN (HIV)
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P17
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MATRIX PROTEIN (HIV)
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TAT
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HIV
VIRAL TRANSACTIVATOR (PROMOTES TXN) |
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REV
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regulates splicing
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GAG-POL
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Ribosomal frameshift allows for two gene products from one RNA
gag = budding machine pol = polymerase |
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HIV PROTEASE
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Cleaves precursor Gag & gag-pol proteins to form new prtoein
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X4,R5, XR45
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HIV coreceptors; Effects memory cells
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VIF
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mediates degradation of Tetherin which acts to prevent release of viral particles
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how HIV is controlled
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CTL
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CCR5 deletion is risk factor for which virus
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West Nile Virus (helpful for HIV though)
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N protein (rapibes)
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txn, replication
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L protein (rabies)
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polymerase
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NS protein (rabies)
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Non-structural polymerase
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M protein
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Matrix protein (assembly & budding)
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cd56
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Receptor in neurons for Rabies
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Ds RNA 11 genomic segments
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Rotavirus
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VP 4
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cell attachment, hemaggluttination, neutralizing epitopes
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VP6
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Major group Ag
rotavirus |
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VP7
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G antigen (neutralizing epitopes)
rotavirus |
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NSP4
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Enterotoxin (rotavirus)
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Outer capsid (rotavirus)
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VP4/7
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Inner Capsid (rotavirus)
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VP6
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Cor protein (rotavirus)
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VP2
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3 Open Reading frames: What virus
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Noravirus
ORF1 = replication ORF2 = Capsid protein VP1 ORF3 = unknown (VP2) |
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Partially dsDNA circular virus
smallest Virus |
HBV
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CD46
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Receptor for measles
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E1-4 (HPV)
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Replication proteins
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E6-7 (HPV)
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oncogenetic proteins (HPV
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L1 HPV
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Capsid protein (vaccine antigen)
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L2 (HPV)
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capsid protein (minor)
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Latent Site HSV1
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Geniculate Ganglion
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Latent site HSV2
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DRG
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Latency site VZV
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DRG
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cd21
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EBV
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UL 54
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CMV; DNA polymerase
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UL 97 PROTEIN
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CMV Kinase, phosphorylates gancyclovir
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Inclusion Bodies
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DX for cmv
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E2 mediated attachment
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HCV
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NS3/4A PROTEASE
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HCV - prevents IFN -B induction
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Hep E dangerous trimester
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3rd
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CMV dangerous trimester
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1st
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GAG
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nucleocapsid protein
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NEF
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HIV
DOWNREGULATES MHC1 and CD4 expression (reduces chance of CD8 killing) |
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VIF
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viral infectivity factor
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Herepes Envelope
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From the nucleus not the CELL MEMBRANE!
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Heparan sulfate
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Cellular receptor for herpes
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