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37 Cards in this Set
- Front
- Back
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What is the end-point of viral hepatitis? |
Cirrhosis |
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Nucleic acid category of Hep. A |
ss RNA |
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Nucleic acid category of Hep. B |
ds-DNA |
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Nucleic acid category of Hep. C |
ss-RNA |
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Nucleic acid category of Hep. delta |
ss-RNA |
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Nucleic acid category of Hep. E |
ss-RNA |
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What are the 2 types of hepatitis that are transmitted fecal-orally? |
Hep. A and E (exam i think) |
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T or F, all hepatitis viruses are related in some sort of way |
FALSE. None of the hepatitis are related. They are only grouped together because they affect the liver |
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Transmission of Hep. A |
Fecal-oral (exam i think) |
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Which Hep. is associated with consumption of contaminated foods (esp. water and shellfish) |
Hep. A |
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T or F, Hep. A is associated with chronic hepatitis and/or hepatic cancers |
False. NOT associated |
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Which type of Hep. can cause jaundice in adults? |
Hep. A |
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Which Ig's will increase progressively after infection of Hep. A? Which will decrease? |
Increase: IgG Decrease: IgM |
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T or F, Hep. E can cause chronic hepatitis |
FALSE. |
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WHICH HEP. IS THIS: Infection may lead to fulminant hepatic failure in pregnant women |
Hep. E |
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Where is the highest burden of Hep. B in the world? |
West Africa |
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What type of transmission constitutes the majority of cases of Hep. B in West Africa? |
Perinatal |
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Modes of transmission of Hep. B |
Blood (most common), semen (exam i think) |
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Which is more like to end up in a chronic hepatitis (re: Hep. B), perinatal transmission OR adults infection/acute hepatitis |
Perinatal (90% will end up in chronic infection).... acute hepatitis only accounts for ~5% of chronic hepatitis |
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Immune clearance VS. immune tolerance... when do most symptoms occur? |
Immune clearance |
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What test do you order if you want to know if your patient is currently infected with Hep. B |
Surface antigen test (HepBsAg) (on exam i think) |
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What test do you order if you want to know if your patient has ever been exposed to Hep. B |
Core antibody (HepBcAb) (on exam i think) |
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What test do you order if you want to know if your patient is immune to Hep. B |
Surface antibody (HepBsAb) (on exam i think) |
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What test do you order if you want to know if your patient have an acute Hep. B infection |
Core IgM test. (HepBcIgM) (on exam i think) |
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#1 way to prevent against Hep. B? |
VACCINATE!!!! |
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#1 goal of treatment of Hep. B infection |
Suppress HBV replication. It's a DNA virus, which is very stable so you cannot really completely remove it from the patient that is infected. So you want to suppress replication as much as you can |
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Hep D is dependent on _____ for production of envelope proteins |
Hep. B. (i.e. you can only get Hep. D infection in the presence of Hep. B) |
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#1 cause of Hep. C transmission |
Injection drug use (exam i think) |
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T or F, Hep. C will progress to chronic infection in ~80% of cases |
TRUE.
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How is Hep. C diagnosed? (2) |
1) presence of HCV Ab in the blood 2) presence of HCV RNA in the blood |
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#1 indication for liver transplantation secondary to Hep. C infection |
Liver failure |
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T or F, prevention of Hep. C = vaccination |
FALSE. There is no vaccine against Hep. C |
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T or F, you cannot cure Hep. C, treatment goals are basically to suppress viral replication |
FALSE. You can cure this one (not like in the case of Hep. B) |
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Treatment for HBV? (2) |
IFN alpha Nucleoside/nucleotide inhibitors (on exam i think) |
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Treatment for HCV? (2) |
IFN alpha Ribavarin (on exam i think) |
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Needle-stick injuries, we are worried about: (3) |
1) HBV 2) HCV 3) HIV |
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Out of the 3 types viral agents that can result from a needle-stick injury, which one is the most infectious? |
HBV |
