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4 Cards in this Set

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What is viral neutralization?

When a virus undergoes a loss of infectivity due to antibodies

What are some of the mechanisms by which a virus can be neutralised?

1. Aggregating viral particles together


2. Inhibiting the attachment of viruses to cell receptors


3. Inhibiting viral uncoating and fusion

What is the mechanism of action of non-neutralizing antibodies?

They will bind to a virus but not kill the virus. If the virus has no cell receptor for a neutralising antibody to bind to, the non-neutralising antibody acts as a surrogate receptor.

What can be a major problem with non-neutralising antibodies?

If there are too many non-neutralizing antibodies attached to a virus, the neutralising antibody can't bind.