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116 Cards in this Set
- Front
- Back
for caudal anesthesia, what
landmarks are palpated for the injection to be made at the sacral hiatus? |
palpation of the depression
between the sacral cornua is the best place (these ar eon either side of the sacral hiatus) |
|
what 2 nerves are anesthetized in
a popliteal block? |
tibial and common peroneal
nerves (divisions of the sciatic nerve) |
|
which ester local anesthetic is a
weak acid? what is the pKa |
Benzocaine (ethyl benzoate)
pKa of 3.5 all others locals are bases with Pka ranginf from 7.6-9.1 |
|
what form (mostly ionized
or mostly nonionized) exists when benzocaine encounters physiological pH? |
mostly ionized
|
|
benzocaine is best clinically used
how? |
topical anesthesia for mucous
membranes this is b/c it is hgihly iionized at physiologic pH |
|
what is recommended max dose
for topical benzocaine? |
200-300 mg
20% benzocaine only requires a brief spray and that is max. dose -r/o methemoglobinemia |
|
what local anesthetics make up
EMLA cream |
Prilocaine 2.5% and lidocaine
2.5% |
|
can methemoglobinemia occur
with EMLA cream? |
yes b/c prilocaine is in it
children are more susceptible (3- 12 months): have immature reductase pathways |
|
4 contraindications to EMLA
cream |
-mucous membranes
-open wounds -pt on mexilitine -pt with history of allergy to amides |
|
4 elements compromising hte
"anatomy of medical negligence action" |
-duty
-breach -damage -cause |
|
define "proximate cause"
|
a cause that was foreseeable
before theevent took place |
|
2 common tests used to establish causation
|
but for test: if accident
would not have occurred, but for the actions of the plaintiff substantial factor: if the act of the defendent was a substantial factor in the injury |
|
in addition to barbiturate and
propofol, what 3 other anesthetic agents are compatible with SSEP monitoring? |
ketamine, opioids, etomidate
|
|
how is sterilization different from
disinfection? |
disinfection does not destroy
bacterial pores |
|
is pateurization a high level
disinfection? |
yes; equipment is immersed in
water at high temperature (70 degrees C) for 30 minutes |
|
what is autoclaving
|
Steam sterilization: utilizes
saturated steam under pressure (temepratures exceed 100 degrees C) |
|
when do fat embolism syndrome
(FES) symptoms usually manifest |
12-72 hours after the insult
|
|
what agent may be given
prophylactically for pts at risk of a fat emboli? |
corticosteroids: they may limit the endothelial damage done by the free fatty acids
|
|
what triad of symptoms should
arouse suspicion of fat embolus? |
-petechiae
-hypoxemia -mental confusion |
|
major criteria for diagnosis fo fat
emboli |
-axillary/subconjunctival
-ptechiae -hypoxemia -CNS depression pulmonary edema |
|
minor criteria for diagnosis fo fat
emboli |
-increaed HR
-hyperthermia -jaundice -retinal fat emboli -renal changes |
|
what is the most consistent
symptom of acute pulmonary embolism? |
sudden, acute dyspnea
|
|
what laboratory test when positive is consistent with a PE, but when negative suggests thromboembolism is absent
|
D-dimer: positive means a PE is
possible and negative means that there isn't one |
|
is a mill wheel murmur heard by
esophageal stehoscope an early or late sign of venous air embolism |
late sign
|
|
early signs of VAE
|
sudden decrease in ETCO2 and
arterial hypoxemia |
|
3 causes of death from a VAE
|
-vapor lock casusing right
side cardiac output to plummet -acute cor pulmonale -arterial hypoxemia from combined cardiac and pulmonary insults |
|
five steps to managing a gas
embolism durng a laparoscoic sugery: |
-halt insufflation
-shut off nitrous -release the pneumoperitoneum -place pt in left lateral decub -aspirate gas through central line |
|
what may result from excessive
cervical flexion in the beach chair |
this can impede arterial and
venous blood fow cuasing hypoperfusin of venous congestion of the brain can alslo obstruct ETT or put pressure on tongue leading to macroglossia |
|
how many fingerbreadths should be maintained b/t the chin and sternum during beach chair position to prevent excessive cervical flexion
|
2
|
|
there are 4 natriuric peptides in
the body: |
ANP: atrial
BNP:ventricular muscle CNP: endothelial walls of major vessels Urodilatin: urinary tract |
|
what do the natriuric peptides do?
|
they are mostly released in
response to increased volume at their areas the induce arterial and venous dilation, increase RBF and GFR, and suppress the actions of epi, norepi, renin |
|
what is the cyclic nucleotide
second mesanger that mediates the cellular actions of natriuric pepetides |
cGMP
|
|
what is Virchow's triad
|
3 primary abnormlties in
hemosstasis that lead to thrombus formation: -endothelial injury -stasis or turbulent blood flow -hypercoagulability of the blood |
|
what is phase I on the capnograph
|
end of inspiration= CO2 levels are near 0
|
|
what is phase II on the
capnograph? |
emptying of the connecting
airways and beginning of emptying of alveoli. mixture of anatomic and alveolar dead space (Area in the lung with high V/Q ratio) |
|
what is phase III on the
capnograph |
alveolar plateau: emptying of the
alveoli |
|
what is phase IV on the
capnograph? |
inspiration: CO2 abruptly falls
|
|
what does an increased alpha
angle on a capnograph mean |
means that the slope is more
slanted, so the lungs are taking to exhale deadspace volume. this is seen in obstructive disease or with PEEP |
|
what would cause the beta angle
on the capnograph to be increased on the capnograph? |
rebreathing
|
|
what is a double circuit ventilator
|
one circuit contains patient gas and the other circiut contains the drive gas
common on modern machines: separates the breathing system gas form the driving gas |
|
what % of the CO traverses
bronchial circulation? vessels dellivering blood to the bronchial circulation arise from what arteries? |
1-2%
thoracic aorta intercostal arteries |
|
which neurotransmitter is the
most common excitatory nt in the CNS |
glutamate
|
|
**List 3 common inotropic
glutamate receptors in the CNS. which electrolytes pass through these receptors upon activation? |
-NMDA
-AMPA -Kainate Na, Ca in and K out |
|
describe the anatomy of the
hypogastric plexus |
-retroperitoneal structure that is
formed by the confluence of the bilateral lumbar sympathetic chains -pelvic pain that is caused by inflammatory disease or cancer can be relieved by interruption of the bilateral sympathetic pathways which can be achieved with a superior hypogastric plexus block |
|
which zona of the adrenal cortex
is the only one capable of synthesizing aldosterone |
Zone glomerulosa; bc this is the
only one that has aldosterone synthase |
|
Identify 2 stimuli in addition to
the decreased renal perfusion pressure for the release of renin |
-sympathetic nervous system
stimulation -hyponatremia |
|
normal hemoglobin (hbg A) has
what globin chains |
2 beta chains and 2 alpha chains
|
|
what is hemoglobin-S and how
does it differ from hemoglobin-A |
In sickle cell anemia Hbg-S has a
valine instead of glutamic acid in the sixth postition o fhte beta chain on the Hbg molecule |
|
what lymphocytes mediate
humoral immunity? cell-mediated immunity? |
Humoral: B lymphocytes
cell-mediated: T lymophocytes |
|
ketamine acts on what CNS
receptor? |
NMDA: antagonizes
-this is a subtype of glutamate recetpor |
|
list the ester local anesthetics
|
cocaine
procaine chloroprocaine tetracaine benzocaine |
|
maximum dose with and without
epi for: -lidocaine -mepivicaine -bupicaine -ropivicaine |
plain and (with epi)
lidocaine: 300 mg (500) mepivicaine:300 mg (500) bupiviciane: 175 mg (225) ropiviciane: 300 mg |
|
At what pressure should the O2
E-cylinder on an anesthesia machine be changed |
when the pressure is <1000 psi
(half full) |
|
4 elements of the anesthesia
machine that are exposed to High pressures |
-hanger yoke
-yoke block with check valves -cylinder pressure gauge -cylinder pressure regulators |
|
what complications can occur
during the wake up test? |
-extubation in the prone postition
-recall of intraop events (0-20%) -myocardial ischemia -self injury -air embolus (if pt breathing spontaneously and inhales vigorously) |
|
the wake-up test monitors what
region of the spinal cord? (dorsal/lateral/ ventral) |
ventral: supplied by the anterior spinal artery
pt asked to squeeze hand |
|
what is the wake-up test used for?
|
used to assess the integrigy of the spinal motor pathways
(ventral/anterior) |
|
what is the most likely reason a pt who undergoas a non-opthalmic procedure develops blindness
postoperatively |
optic nerve and retinal ischemia
from compression of the eye (prone position) or systemic hypotension |
|
if pt in lateral position with no
axillary roll and O2 sat on dependent hand starts to desat, what is most likely problem |
compression of the axillary
neurovascular bundle; compromising blood flow to the hand |
|
2 reasons why a chest roll is
placed under pt in lateral decub position |
lift thorax and relieve pressure on the axillary neurovascular bundle:
-preventing injury to brachial plexus -prevent reduced blood flow to the hand |
|
how can compartment syndrome
in a leg be precipitated? |
-intraoperative hypotension
in conjunction with leg elevation that causes low flow rates -pneumatic compression boots and fluid extravasation into tissues -vascular obstruction of major blood vessels between pelvic retractors -excessive flexion of knees or hips |
|
what is the treatment for
compartment syndrome |
fasciotomy
|
|
what is Bullard laryngoscope?
when is it useful? |
rigid fiberoptic laryngoscope for indirect laryngoscopy: useful when movement of pt head/neck is contraindicated or limited oral aperture
Key feature: oral, pharyngeal, and tracheal axes do not |
|
controlled hypotension can result
in many complications, what pt population is at increased risk of these? |
pt with coexisting anemia
|
|
what are the most frequent
dysrhythmias during extracorpeal shock wave lithotripsy (ESWL) |
PVC's and PAC's
|
|
what are 2 signs of fetal hypoxia?
|
fetal bradycardia and late
decelerations indicate fetal hypoxia |
|
Identify 5 signs and symptoms of
venous air embolism in the pregnant pt |
-millwheel murmur over
-pericardium -chest pain -dyspnea -decreased ETCO2 -elevated CVP |
|
what is the most common type of
postoperative delirium in the elderly |
interval delerium: occurs after a
lucid interval of one or more days after operation |
|
what is the % incidence of post-op delerium in the elderly and after what type of durgery is it most common
|
10-15%
orthopedic |
|
what is the most effective
measure for pain associated with pancreatic cancer? |
celiac plexus block with alcohol
or pheon |
|
what is the difference b/t an
expert witness and a factual witness |
according to ASA guideline, there should be no difference
legally: an expert witness can give opinions and a factual witness cannot |
|
List the 3 descriptive statistics
that specify the central tendency, or middle, of numerical data |
-median: center or midpoint
when it is arranged from least to greatest -mode: most frequently occuring value -mean: arithmatic average of the numbers |
|
How is the standard of care
established? what 2 sources are typically consulted to establish the standard of care? |
standard of care is what the jury says it is. two sources:
-beliefs offered by expert witness -the published standards of care, guidelines, practice parameters and protocols |
|
what are the 2 types of complex regional pain syndromes and what
is the main difference b/t the two? |
-CRPS type I: reflex sympathetic dystrophy
-CRPS Type II: causlagia in Type II, there is a documented nerve injury preceding the CRPS |
|
which volatile anesthetic is not an ether?
|
halothane
|
|
which of the volatiles are methyl
ethyl ethers? |
enflurane, isoflurane and
desflurane |
|
since Sevo is not a methyl ethyl
ether, what type of ether derivative is Sevo? |
methyl isopropyl ether
|
|
which 2 volatiles are isomers of
each other? |
enflurane and isoflurane
|
|
which inhaled anesthetic is the
only one containing Bromide |
halothane
|
|
what is the medical management
ant tretement for CRPS in children |
physical therapy
may need pharmacological treatment to allow for PT, so membrane stabilizers (neurontin and tricyclic antidepressants) |
|
what regional block may be indicated for circulatory insufficiency of the upper extremity or for relief of CRPS affecting an upper extremity
|
stellate ganglion block
(cervicothoracic sympathetic block) |
|
what is the advantage of using a
Jackson table for wilson frame |
orthopedic frames
-don't compress chest and abdomen when in prone position so maintain normal pulmonary compliance -minimize abdominal pressure, so the inferior vena cava is not impaired and venous return is optimized |
|
which volatile differs from Iso
only by replacement of the chlorine with fluorine? |
Desflurane (this one change
increase the VP dramatically 669 compared to 240) |
|
which 2 anesthetics have only
fluorine as the halogen substitute? |
Des and Sevo
(this makes them less soluble in the blood) |
|
what is "context sensitive halftime"?
|
the time necessary for the plasma drug concnetration to decreased by 50% after discontinuing a continuous infuction of a specific
duration *considers the combined effects of distribution and metabolism as well as duration of IV administration |
|
BAEPs are usually very resistant to alteration by anything other than structural pathology in the brainstem. What OR room environment variable with "decreased latency and prolonged interpeak intervals?"
|
mild hypothermia
|
|
what driving pressure is needed to generate sufficient gas flow for transthracheal jet ventialtion thru a 12 or 14 gauge catheter?
|
50 psi
|
|
chemical name for etomidate
|
it is an imidazole derivative
(R-pentylethyl-1H-imadazole-5 caboxylate sulfate) |
|
what is the more comon name of
2-O-chlorophenyl-2-methylamino cyclohexanone hydrochloride |
Ketamine
|
|
above what ICP will a "vicous
cycle" of ischemia and edema ensue? |
>30 mmHg
|
|
during ECT what is the desired
duration of the seizure |
30-60 seconds
|
|
how many total seizure seconds
of ECT therapy are generally needed to see a good therapuetic effect? |
400-700 seconds. sicne each sz is 30-60 seconds and can only have 1/day, may take several weeks to see effects
|
|
what is GPIIb/IIIa
|
platelet glycoprotein; platelet
fibrinogen receptor: it binds circulating fibrinogen and promotes platelet aggregation, leading to a plt plug |
|
name 3 GPIIb/IIIa inhibitors
primary use are they reversible |
-Abciximab (Reopro): 12-24 hour elimination time
-Eptifibatide (Integrillin):2-4 hours -Tirofiban (Aggrastat): 2-4 hours prevent plt aggregation: acute coronary syndromes and percutaneous coronary interventions they are reversible: |
|
what is the major intraop
anesthetic goal for renal transplantation? |
maintenance for renal blood flow
SBP>90 MAP>60 CVP>10 |
|
How long should
immunosuppressive treatment be continued after transplant? |
lifelong
|
|
what type of drugs are tacrolimus
and cyclosporine |
immunosuppressant drugs used after transplant surgery
calcinuerin inhibitors: they inhibit T-lymphocyte proliferation DNA cytokine production |
|
during liver tranplant,
severe acidosis during the dissection phase should be treated with what drug |
THAM: tris-hydroxymethyl
aminomethane infusion |
|
at what point during pregnancy is
cardiac output greatest |
end of the second trimester
|
|
EBV for:
premie neonate 3m - 3yr >6yr |
premie: 90-100 ml/kg
nonate: 80-90 ml/kg 3m-3yr: 75-80 ml/kg >6yr: 65-70 ml/kg |
|
a lidocaine spinal anesthetic was administered for an arthroscopic procedure on the left knee.
post-op pt c/o pain in the buttocks. what might have occurred |
Pain or dysesthesia in buttocks or legs following a spinal with lidocaine are classic symptoms of
transient neurologic symptoms (TNS) symptoms will disappear within 10 days |
|
what is another name for transient neurological symptoms (TNS)
|
post spinal pain syndrome
|
|
in transtracheal ventilation if 50 psi is used what wil the delivery of O2 (flow rate) be thru:
-20 gauge catheter -16g -14g |
20g = 400 ml/second
16g = 500 ml/second 14g = 600 ml/second |
|
3 complications of transtracheal
jet ventilation? |
-problems with exhalation
-barotrauma -tissue emphysema |
|
when does maternal CO begin to
increase during pregnancy |
5th week gestation
|
|
name 3 types of double lumen
tubes |
carlens: left
white: right robert shaw (both bronchi) |
|
what is the most accurate method for determining correct double lumen tube placement
|
flexible endoscopy
|
|
what is the optimal shape of the
lighted stylet for nasal intubation |
for nasal intubation, the shape
should be prepared against the patient profile |
|
what antihypertensive is now
considered first line treatment for HTN in the preeclamptic pt? |
Labetalol (normodyne)
|
|
list 3 other names for idiopathic
hypertrophic subaortic stenosis (IHSS) |
-hypertrophic
cardiomyopathy (HCM) -hypertrophic obstructive cardiomyopathy (HOCM) -asymmetric septal hypertrophy |
|
list the anesthetic hemodynamic
goals for the pt iwth IHSS |
-sinus rhythm
-full: increased preload -increased afterload -slightly depressed -contractility -nl HR |
|
5 complications of the
interscalene block |
- Horner's syndrome
-Hoarsensess - recurrent laryngeal nerve - ipsilateral hemdiaphragmatic paresis (phrenic nerve is blocked): very common and not an issue unless pt has resp disease at baseline -cough or chest pain (pneumothorax) -Bezold-Jarisch reflex: sudden bradycardia and hypotension inthe sitting position |
|
what is the leading non-obstetric
cause of mortality in the pregnant pt? |
heart disease
|
|
what spinal nneedles are
-pencil point -cutting? -non-cutting? |
pencil point: sprotte and whitacre
cutting: Quincke no-cutting: Greene |
|
what is normal BMI?
-overweight -obese -severe obesity -morbidly obese |
18.5-24.9
Overwt: 25-29 Moderate obesity: 30-34 severe obesity: 35-39 morbidly obese: 40-49 |
|
what is the HCT of 1 unit of
PRBCs |
75%
|