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116 Cards in this Set

  • Front
  • Back
for caudal anesthesia, what
landmarks are palpated for the
injection to be made at the sacral
hiatus?
palpation of the depression
between the sacral cornua is the best place (these ar eon either side
of the sacral hiatus)
what 2 nerves are anesthetized in
a popliteal block?
tibial and common peroneal
nerves (divisions of the sciatic
nerve)
which ester local anesthetic is a
weak acid? what is the pKa
Benzocaine (ethyl benzoate)
pKa of 3.5

all others locals are bases with
Pka ranginf from 7.6-9.1
what form (mostly ionized
or mostly nonionized) exists when benzocaine encounters
physiological pH?
mostly ionized
benzocaine is best clinically used
how?
topical anesthesia for mucous
membranes

this is b/c it is hgihly iionized at
physiologic pH
what is recommended max dose
for topical benzocaine?
200-300 mg

20% benzocaine only requires a brief spray and that is max. dose

-r/o methemoglobinemia
what local anesthetics make up
EMLA cream
Prilocaine 2.5% and lidocaine
2.5%
can methemoglobinemia occur
with EMLA cream?
yes b/c prilocaine is in it
children are more susceptible (3-
12 months): have immature
reductase pathways
4 contraindications to EMLA
cream
-mucous membranes
-open wounds
-pt on mexilitine
-pt with history of allergy to
amides
4 elements compromising hte
"anatomy of medical negligence
action"
-duty
-breach
-damage
-cause
define "proximate cause"
a cause that was foreseeable
before theevent took place
2 common tests used to establish causation
but for test: if accident
would not have occurred,
but for the actions of the
plaintiff

substantial factor: if the act
of the defendent was a
substantial factor in the
injury
in addition to barbiturate and
propofol, what 3 other anesthetic
agents are compatible with SSEP
monitoring?
ketamine, opioids, etomidate
how is sterilization different from
disinfection?
disinfection does not destroy
bacterial pores
is pateurization a high level
disinfection?
yes; equipment is immersed in
water at high temperature (70
degrees C) for 30 minutes
what is autoclaving
Steam sterilization: utilizes
saturated steam under pressure
(temepratures exceed 100 degrees C)
when do fat embolism syndrome
(FES) symptoms usually manifest
12-72 hours after the insult
what agent may be given
prophylactically for pts at risk of
a fat emboli?
corticosteroids: they may limit the endothelial damage done by the free fatty acids
what triad of symptoms should
arouse suspicion of fat embolus?
-petechiae
-hypoxemia
-mental confusion
major criteria for diagnosis fo fat
emboli
-axillary/subconjunctival
-ptechiae
-hypoxemia
-CNS depression
pulmonary edema
minor criteria for diagnosis fo fat
emboli
-increaed HR
-hyperthermia
-jaundice
-retinal fat emboli
-renal changes
what is the most consistent
symptom of acute pulmonary
embolism?
sudden, acute dyspnea
what laboratory test when positive is consistent with a PE, but when negative suggests thromboembolism is absent
D-dimer: positive means a PE is
possible and negative means that
there isn't one
is a mill wheel murmur heard by
esophageal stehoscope an early or late sign of venous air embolism
late sign
early signs of VAE
sudden decrease in ETCO2 and
arterial hypoxemia
3 causes of death from a VAE
-vapor lock casusing right
side cardiac output to
plummet

-acute cor pulmonale

-arterial hypoxemia from
combined cardiac and
pulmonary insults
five steps to managing a gas
embolism durng a laparoscoic
sugery:
-halt insufflation

-shut off nitrous

-release the pneumoperitoneum

-place pt in left lateral decub

-aspirate gas through central
line
what may result from excessive
cervical flexion in the beach chair
this can impede arterial and
venous blood fow cuasing
hypoperfusin of venous
congestion of the brain
can alslo obstruct ETT or put
pressure on tongue leading to
macroglossia
how many fingerbreadths should be maintained b/t the chin and sternum during beach chair position to prevent excessive cervical flexion
2
there are 4 natriuric peptides in
the body:
ANP: atrial

BNP:ventricular muscle

CNP: endothelial walls of
major vessels

Urodilatin: urinary tract
what do the natriuric peptides do?
they are mostly released in
response to increased volume at their areas the induce arterial and venous dilation, increase RBF and GFR,
and suppress the actions of epi, norepi, renin
what is the cyclic nucleotide
second mesanger that mediates
the cellular actions of natriuric
pepetides
cGMP
what is Virchow's triad
3 primary abnormlties in
hemosstasis that lead to thrombus formation:

-endothelial injury
-stasis or turbulent blood
flow
-hypercoagulability of the
blood
what is phase I on the capnograph
end of inspiration= CO2 levels are near 0
what is phase II on the
capnograph?
emptying of the connecting
airways and beginning of
emptying of alveoli. mixture of
anatomic and alveolar dead space
(Area in the lung with high V/Q
ratio)
what is phase III on the
capnograph
alveolar plateau: emptying of the
alveoli
what is phase IV on the
capnograph?
inspiration: CO2 abruptly falls
what does an increased alpha
angle on a capnograph mean
means that the slope is more
slanted, so the lungs are taking to exhale deadspace volume.

this is seen in obstructive disease or with PEEP
what would cause the beta angle
on the capnograph to be increased on the capnograph?
rebreathing
what is a double circuit ventilator
one circuit contains patient gas and the other circiut contains the drive gas
common on modern machines:
separates the breathing system gas form the driving gas
what % of the CO traverses
bronchial circulation?
vessels dellivering blood to the
bronchial circulation arise from
what arteries?
1-2%
thoracic aorta
intercostal arteries
which neurotransmitter is the
most common excitatory nt in the
CNS
glutamate
**List 3 common inotropic
glutamate receptors in the CNS.
which electrolytes pass through
these receptors upon activation?
-NMDA
-AMPA
-Kainate

Na, Ca in and K out
describe the anatomy of the
hypogastric plexus
-retroperitoneal structure that is
formed by the confluence of the bilateral lumbar sympathetic chains

-pelvic pain that is caused by
inflammatory disease or cancer can be relieved by interruption of the bilateral sympathetic pathways which can be achieved with a superior hypogastric plexus
block
which zona of the adrenal cortex
is the only one capable of
synthesizing aldosterone
Zone glomerulosa; bc this is the
only one that has aldosterone
synthase
Identify 2 stimuli in addition to
the decreased renal perfusion
pressure for the release of renin
-sympathetic nervous system
stimulation

-hyponatremia
normal hemoglobin (hbg A) has
what globin chains
2 beta chains and 2 alpha chains
what is hemoglobin-S and how
does it differ from hemoglobin-A
In sickle cell anemia Hbg-S has a
valine instead of glutamic acid in
the sixth postition o fhte beta
chain on the Hbg molecule
what lymphocytes mediate

humoral immunity?
cell-mediated immunity?
Humoral: B lymphocytes
cell-mediated: T lymophocytes
ketamine acts on what CNS
receptor?
NMDA: antagonizes

-this is a subtype of glutamate
recetpor
list the ester local anesthetics
cocaine
procaine
chloroprocaine
tetracaine
benzocaine
maximum dose with and without
epi for:

-lidocaine
-mepivicaine
-bupicaine
-ropivicaine
plain and (with epi)
lidocaine: 300 mg (500)
mepivicaine:300 mg (500)
bupiviciane: 175 mg (225)
ropiviciane: 300 mg
At what pressure should the O2
E-cylinder on an anesthesia
machine be changed
when the pressure is <1000 psi
(half full)
4 elements of the anesthesia
machine that are exposed to High
pressures
-hanger yoke
-yoke block with check
valves
-cylinder pressure gauge
-cylinder pressure regulators
what complications can occur
during the wake up test?
-extubation in the prone postition

-recall of intraop events (0-20%)

-myocardial ischemia

-self injury

-air embolus (if pt breathing
spontaneously and inhales vigorously)
the wake-up test monitors what
region of the spinal cord?
(dorsal/lateral/ ventral)
ventral: supplied by the anterior spinal artery

pt asked to squeeze hand
what is the wake-up test used for?
used to assess the integrigy of the spinal motor pathways
(ventral/anterior)
what is the most likely reason a pt who undergoas a non-opthalmic procedure develops blindness
postoperatively
optic nerve and retinal ischemia
from compression of the eye
(prone position) or systemic
hypotension
if pt in lateral position with no
axillary roll and O2 sat on
dependent hand starts to desat,
what is most likely problem
compression of the axillary
neurovascular bundle;
compromising blood flow to the
hand
2 reasons why a chest roll is
placed under pt in lateral decub
position
lift thorax and relieve pressure on the axillary neurovascular bundle:

-preventing injury to
brachial plexus

-prevent reduced blood flow
to the hand
how can compartment syndrome
in a leg be precipitated?
-intraoperative hypotension
in conjunction with leg
elevation that causes low flow
rates

-pneumatic compression
boots and fluid
extravasation into tissues

-vascular obstruction of major blood vessels between pelvic retractors

-excessive flexion of knees or hips
what is the treatment for
compartment syndrome
fasciotomy
what is Bullard laryngoscope?
when is it useful?
rigid fiberoptic laryngoscope for indirect laryngoscopy: useful when movement of pt head/neck is contraindicated or limited oral aperture

Key feature: oral, pharyngeal, and tracheal axes do not
controlled hypotension can result
in many complications, what pt
population is at increased risk of
these?
pt with coexisting anemia
what are the most frequent
dysrhythmias during extracorpeal
shock wave lithotripsy (ESWL)
PVC's and PAC's
what are 2 signs of fetal hypoxia?
fetal bradycardia and late
decelerations indicate fetal
hypoxia
Identify 5 signs and symptoms of
venous air embolism in the
pregnant pt
-millwheel murmur over
-pericardium
-chest pain
-dyspnea
-decreased ETCO2
-elevated CVP
what is the most common type of
postoperative delirium in the
elderly
interval delerium: occurs after a
lucid interval of one or more days
after operation
what is the % incidence of post-op delerium in the elderly and after what type of durgery is it most common
10-15%
orthopedic
what is the most effective
measure for pain associated with
pancreatic cancer?
celiac plexus block with alcohol
or pheon
what is the difference b/t an
expert witness and a factual
witness
according to ASA guideline, there should be no difference
legally: an expert witness can give opinions and a factual witness cannot
List the 3 descriptive statistics
that specify the central tendency,
or middle, of numerical data
-median: center or midpoint
when it is arranged from
least to greatest

-mode: most frequently
occuring value

-mean: arithmatic average of
the numbers
How is the standard of care
established? what 2 sources are
typically consulted to establish the standard of care?
standard of care is what the jury says it is. two sources:

-beliefs offered by expert
witness

-the published standards of care, guidelines, practice parameters and protocols
what are the 2 types of complex regional pain syndromes and what
is the main difference b/t the two?
-CRPS type I: reflex sympathetic dystrophy

-CRPS Type II: causlagia
in Type II, there is a documented nerve injury preceding the CRPS
which volatile anesthetic is not an ether?
halothane
which of the volatiles are methyl
ethyl ethers?
enflurane, isoflurane and
desflurane
since Sevo is not a methyl ethyl
ether, what type of ether
derivative is Sevo?
methyl isopropyl ether
which 2 volatiles are isomers of
each other?
enflurane and isoflurane
which inhaled anesthetic is the
only one containing Bromide
halothane
what is the medical management
ant tretement for CRPS in
children
physical therapy
may need pharmacological
treatment to allow for PT, so
membrane stabilizers (neurontin and tricyclic antidepressants)
what regional block may be indicated for circulatory insufficiency of the upper extremity or for relief of CRPS affecting an upper extremity
stellate ganglion block

(cervicothoracic sympathetic block)
what is the advantage of using a
Jackson table for wilson frame
orthopedic frames

-don't compress chest and
abdomen when in prone
position so maintain
normal pulmonary
compliance

-minimize abdominal
pressure, so the inferior
vena cava is not impaired
and venous return is
optimized
which volatile differs from Iso
only by replacement of the
chlorine with fluorine?
Desflurane (this one change
increase the VP dramatically 669
compared to 240)
which 2 anesthetics have only
fluorine as the halogen substitute?
Des and Sevo
(this makes them less soluble in
the blood)
what is "context sensitive halftime"?
the time necessary for the plasma drug concnetration to decreased by 50% after discontinuing a continuous infuction of a specific
duration

*considers the combined effects of distribution and metabolism as well as duration of IV administration
BAEPs are usually very resistant to alteration by anything other than structural pathology in the brainstem. What OR room environment variable with "decreased latency and prolonged interpeak intervals?"
mild hypothermia
what driving pressure is needed to generate sufficient gas flow for transthracheal jet ventialtion thru a 12 or 14 gauge catheter?
50 psi
chemical name for etomidate
it is an imidazole derivative
(R-pentylethyl-1H-imadazole-5
caboxylate sulfate)
what is the more comon name of
2-O-chlorophenyl-2-methylamino
cyclohexanone hydrochloride
Ketamine
above what ICP will a "vicous
cycle" of ischemia and edema
ensue?
>30 mmHg
during ECT what is the desired
duration of the seizure
30-60 seconds
how many total seizure seconds
of ECT therapy are generally
needed to see a good therapuetic
effect?
400-700 seconds. sicne each sz is 30-60 seconds and can only have 1/day, may take several weeks to see effects
what is GPIIb/IIIa
platelet glycoprotein; platelet
fibrinogen receptor: it binds
circulating fibrinogen and
promotes platelet aggregation,
leading to a plt plug
name 3 GPIIb/IIIa inhibitors
primary use
are they reversible
-Abciximab (Reopro): 12-24 hour elimination time

-Eptifibatide (Integrillin):2-4 hours

-Tirofiban (Aggrastat): 2-4 hours prevent plt aggregation: acute coronary syndromes and
percutaneous coronary
interventions they are reversible:
what is the major intraop
anesthetic goal for renal
transplantation?
maintenance for renal blood flow
SBP>90
MAP>60
CVP>10
How long should
immunosuppressive treatment be
continued after transplant?
lifelong
what type of drugs are tacrolimus
and cyclosporine
immunosuppressant drugs used after transplant surgery
calcinuerin inhibitors: they inhibit T-lymphocyte proliferation DNA
cytokine production
during liver tranplant,
severe acidosis during the
dissection phase should be treated
with what drug
THAM: tris-hydroxymethyl
aminomethane infusion
at what point during pregnancy is
cardiac output greatest
end of the second trimester
EBV for:
premie
neonate
3m - 3yr
>6yr
premie: 90-100 ml/kg
nonate: 80-90 ml/kg
3m-3yr: 75-80 ml/kg
>6yr: 65-70 ml/kg
a lidocaine spinal anesthetic was administered for an arthroscopic procedure on the left knee.

post-op pt c/o pain in the buttocks. what might have occurred
Pain or dysesthesia in buttocks or legs following a spinal with lidocaine are classic symptoms of
transient neurologic symptoms
(TNS) symptoms will disappear within 10 days
what is another name for transient neurological symptoms (TNS)
post spinal pain syndrome
in transtracheal ventilation if 50 psi is used what wil the delivery of O2 (flow rate) be thru:
-20 gauge catheter
-16g
-14g
20g = 400 ml/second
16g = 500 ml/second
14g = 600 ml/second
3 complications of transtracheal
jet ventilation?
-problems with exhalation
-barotrauma
-tissue emphysema
when does maternal CO begin to
increase during pregnancy
5th week gestation
name 3 types of double lumen
tubes
carlens: left
white: right
robert shaw (both bronchi)
what is the most accurate method for determining correct double lumen tube placement
flexible endoscopy
what is the optimal shape of the
lighted stylet for nasal intubation
for nasal intubation, the shape
should be prepared against the
patient profile
what antihypertensive is now
considered first line treatment for
HTN in the preeclamptic pt?
Labetalol (normodyne)
list 3 other names for idiopathic
hypertrophic subaortic stenosis
(IHSS)
-hypertrophic
cardiomyopathy (HCM)

-hypertrophic obstructive
cardiomyopathy (HOCM)

-asymmetric septal
hypertrophy
list the anesthetic hemodynamic
goals for the pt iwth IHSS
-sinus rhythm

-full: increased preload

-increased afterload

-slightly depressed

-contractility

-nl HR
5 complications of the
interscalene block
- Horner's syndrome

-Hoarsensess - recurrent laryngeal nerve

- ipsilateral
hemdiaphragmatic paresis
(phrenic nerve is blocked):
very common and not an
issue unless pt has resp
disease at baseline

-cough or chest pain
(pneumothorax)

-Bezold-Jarisch reflex:
sudden bradycardia and
hypotension inthe sitting
position
what is the leading non-obstetric
cause of mortality in the pregnant
pt?
heart disease
what spinal nneedles are
-pencil point
-cutting?
-non-cutting?
pencil point: sprotte and whitacre
cutting: Quincke
no-cutting: Greene
what is normal BMI?
-overweight
-obese
-severe obesity
-morbidly obese
18.5-24.9

Overwt: 25-29
Moderate obesity: 30-34
severe obesity: 35-39
morbidly obese: 40-49
what is the HCT of 1 unit of
PRBCs
75%