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12 Cards in this Set

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Normal CSF Parameters


WBC's


Glucose


Protein

WBC's: 0-5


Glucose: 40-70


Protein: <40

Bacterial Meningitis CSF analysis:


WBC


Glucose


Protein

WBC: >1000


Glucose: <40


Protein: >250




*Bacteria eat glucose and make proteins

Tuberculosis Meningitis CSF analysis:


WBC


Glucose


Protein

WBC: 5-1000


Glucose: <10


Protein: >250




*TB is extra hungry - consumes glucose

Viral Meningitis CSF analysis:


WBC


Glucose


Protein

WBC: 100-1000


Glucose: normal (40-70)


Protein: <100




*Viruses aren't alive so they don't "eat" glucose and make "a little protein"

Guillan-Barre Meningitis CSF analysis:


WBC


Glucose


Protein

WBC: normal (0-5)


Glucose: normal (40-70)


Protein: 45-1000




*GB is sneaky, only protein may be elevated

Presentation of Herpes Simplex Encephalitis?

Altered mental status


Seizures


Aphasia


Hemiparesis




*Stroke like because it is affecting the brain.

Cryptococcal meningitis testing?

CSF fluid with cryptoccocal antigen test


-High specificity


-Mononuclear cells predominate (lymphocytes)




*Look for HIV or immunosuppressed patient

CSF with >1000 WBC's - etiology?

Bacterial Meningitis

CSF with super low glucose <10 - etiology?

Tuberculosis Meningitis




*Extra hungry

CSF with normal glucose, slightly elevated WBC's and slight protein elevation - etiology?

Viral meningitis


-mainly lymphocytes and negative Gram stain




*Makes a little protein

Cryptococcus Meningitis - CSF reveals?

WBC:<50


Glucose: 30(appx)


Proteins: 100 (slight elevation)




*Subacute course. Patient likely IVDA or HIV+

Cryptococcus Meningitis Treatment?

Amphotericin B and Flucytosine