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30 Cards in this Set
- Front
- Back
Site of metabolic process:
Fatty acid oxidation |
Mitochondria
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Site of metabolic process: Acetyl CoA production
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Mitochondria
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Site of metabolic process:
Krebs Cycle |
Mitochondria
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Site of metabolic process:
Oxidative Phosporylation |
Mitochondria
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Site of metabolic process:
Glysolysis |
Cytoplasm
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Site of metabolic process:
Fatty acid synthesis |
Cytoplasm
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Site of metabolic process:
HMP Shunt |
Cytoplasm
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Site of metabolic process:
Protein synthesis |
Cytoplasm
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Site of metabolic process:
Steroid synthesis |
Cytoplasm
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Site of metabolic process:
Heme synthesis |
Mitochondria and Cytoplasm
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Site of metabolic process:
Urea Cycle |
Mitochondria and Cytoplasm
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Site of metabolic process:
Gluconeogenesis |
Mitochondria and Cytoplasm
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Rate determining enzyme of:
De novo pyrimidine synthesis |
Aspartate transcarbamylase (ATCase)
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Rate determining enzyme of:
De novo purine synthesis |
Glutamine PRPP amidotransferase
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Rate determining enzyme of:
Glycolysis |
Phosphofructokinase (PFK-1)
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Rate determining enzyme of:
Gluconeogenesis |
Pyruvate carboxylase
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Rate determining enzyme of:
TCA cycle |
Isocitrate dehydrogenase
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Rate determining enzyme of:
Glycogen synthesis |
Glycogen synthase
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Rate determining enzyme of:
Glycogenolysis |
Glycogen phosphorylase
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Rate determining enzyme of:
HMP Shunt |
Glucose-6-phosphate dehydrogenase (G6PD)
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Rate determining enzyme of:
Fatty acid synthesis |
Acetyl-CoA carboxylase (ACC)
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Rate determining enzyme of:
Fatty Acid Oxidation |
Carnitine acetyltransferase I
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Rate determining enzyme of:
Ketogenesis |
HMG CoA synthase
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Rate determining enzyme of:
Cholesterol synthesis |
HMG CoA reductase
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Rate determining enzyme of:
Heme synthesis |
ALA synthase
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Rate determining enzyme of:
Urea cycle |
Carbamoyl phosphate synthase I
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Function of glucokinase:
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Phosphorylates excess glucose to sequester it in the liver
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Most potent activator of phosphofructokinase:
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F2, 6BP
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End products of pyruvate metabolic pathways and their function:
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1. Alanine (carries amino groups to liver from muscle)
2. Oxaloacetate (replenish TCA cycle or be used in gluconeogenesis) 3. Acetyl CoA (transition from glycolysis to TCA cycle) 4. Lactate (end of anaerobic glycolysis--major pathway in RBC's, leukocytes, kidney medulla, lens testes, cornea) 3. |
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What is the function of the Cori cycle?
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Allows lactate generated during anaerobic metabolism to undergo hepatic gluconeogenesis and become a source of glucose for RBCs and muscle.
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