Usmle Step 1 Key Associations B

Front 1

Gene involved in cancer

Back 1

p53 tumor suppressor gene

Front 2

Glomerulo-nephritis
Adults

Back 2

Berger's dx
IgA nephropathy

Front 3

Gynecological malignancy
Uterine

Back 3

Endometrial carcinoma

Front 4

Heart murmur

Back 4

Mitral valve prolapse

Front 5

Heart valves in bacterial endocarditis
valve and most common cause

Back 5

Tricuspid (IV drug abuse)
Mitral (rheumatic fever)
Aortic (rheumatic fever 2nd)

Front 6

Helminth infection

Back 6

1. Enterobius vermicularis
2. Ascaris lumbricoides

Front 7

Hematoma epidural

Back 7

Middle meningeal artery rupture
bleed into space btw skull and dura mater
Arterial bleeding is fast

Front 8

Hematoma subdural

Back 8

Bridging veins rupture, esp. trauma
Venous bleeding is slow

Front 9

Hemochromatosis
cause?
inc risk for?

Back 9

Multiple blood transfusions
Can result in CHF
Inc risk hepatocellular carcinoma

Front 10

Hepatocellular carcinoma
associations

Back 10

Cirrhotic liver
Hepatitis B, C

Front 11

Hereditary bleeding disorder
most common

Back 11

von Willibrands dx
A1 domain binds to platelet GP1b receptor

Front 12

Hereditary harmless jaundice

Back 12

Gilbert's syndrome
benign congenital unconjugated hyper-bili-rubinemia

Front 13

HLA-B27 associations

Back 13

Ankylosing spondylitis
Reiter's syndrome
Ulcerative colitis

Front 14

HLA-DR3 or -DR4

Back 14

Diabetes mellitus type 1
Rheumatoid arthritis
SLE

Front 15

Holo-systolic murmur

Back 15

VSD
Tricuspid regurgitation
Mitral regurgitatation

Front 16

Hyper-coag-ulability
Endothelial damage
Blood stasis

Back 16

Virchow's triad
Results in venous thrombosis

Front 17

Hypertension 2o
Main cause

Back 17

Renal dx

Front 18

Hypo-para-thryoidism

Back 18

Thyroidectomy

Front 19

Hypo-pituit-arism
most common cause

Back 19

Adenoma

Front 20

Blood transfusion infection
Commonly transmitted

Back 20

Hepatitis C

Front 21

Kidney stones
3 types, radio-opacity

Back 21

1. Calcium = radi-opaque
2. Struvite (ammonium) = radi-opaque
3. Uric acid = radio-lucent

Front 22

Struvite kidney stones
How formed

Back 22

Urease-positive organisms
Proteus vulgaris
Staphylo-coccus

Front 23

Late cyanotic shunt
(uncorrected L--> R
becomes R --> L)

Back 23

Eisen-menger's syndrome
Caused by ASD, VSD, PDA
Results in pulmonary htn, polycythemia

Front 24

Liver dx
Most common cause

Back 24

Alcoholic liver dx

Front 25

Gaucher dx
Type of dx

Back 25

Lysosomal storage dx

Front 26

Male GU cancer

Back 26

Prostatic carcinoma

Front 27

Malignancy assoc with non-infectious fever

Back 27

Hodgkin's lymphoma

Front 28

Malignant skin tumor

Back 28

Basal cell carcinoma
Rarely metastasizes

Front 29

Mental retardation
Main causes

Back 29

1. Down syndrome
2. Fragile X syndrome

Front 30

Mets to bone
6 main cancers as source

Back 30

Breast
Lung
Thyroid
Testes
Prostate
Kidney

Front 31

Mets to brain
5 main cancers as source

Back 31

Lung
Breast
Skin (melanoma)
Kidney (renal cell carcinoma)
GI

Front 32

Mets to liver
5 main cancers as source

Back 32

Colon
Gastric
Pancreatic
Breast
Lung

Front 33

Mitral valve stenosis
Main cause

Back 33

Rheumatic heart dx

Front 34

Motor neuron dx

Back 34

ALS

Front 35

Myocarditis
Main agent

Back 35

Cox-sackie B

Front 36

Neoplasms kids

Back 36

1. ALL
2. Cerebellar medullo-blastoma

Front 37

Nephrotic syndrome adults

Back 37

Membranous glomerulo-nephritis