Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
15 Cards in this Set
- Front
- Back
Block cell wall synthesis by inhibition of peptidoglycan cross-linking
|
Penicillins
|
|
Name three antibiotics that inhibit peptidoglycan synthesis?
|
Bacitracin, vancomycin, cycloserine
|
|
Blocks mRNA synthesis?
|
Rifampin
|
|
Bactericidal antibiotics?
|
Penicillin,cephalosporins,vancomycin, aminoglycosides, fluoroquinolones, metronidazole
|
|
Disrupt bacterial/fungal cell membranes
|
polymyxins
|
|
Disrupt fungal cell membranes
|
Amphotericin B, nystatin, fluconazole/azoles
|
|
Block DNA topoisomerases
|
Quinolones
|
|
Block nucleotide synthesis
|
sulfonamides, trimethoprim
|
|
Blocks protein synthesis at 30S ribosomal subunit?
|
Aminoglycosides and tetracyclines
|
|
Blocks protein synthesis at 50S ribosomal subunit?
|
Chloramphenicol, erythromycin/macrolides, linomycin, clindamycin, streptogramins, linezolid
|
|
Which penicillin if delivered IV? and Oral?
|
Penicillin G (IV)
Penicillin V (Oral) |
|
Toxicity of penicillin?
|
Hypersensitivity and hemolytic anemia
|
|
Three penicillins resistant to penicillinase due to bulkier R group?
|
Methicillin, nafcillin, dicloxacillin (oxacillin group)
|
|
This penicillin (resistant to penicillinase) has been known for causing interstitial nephritis?
|
Methicillin
|
|
Three mechanisms of penicillin?
|
1. Binds penicillin binding proteins
2. Blocks transpeptidase enzyme 3. Activates autolytic enzymes |