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90 Cards in this Set
- Front
- Back
DNA |
Deoxyribonucleic acid, A double stranded polymer of nucleotides |
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Deoxyrubose sugar |
Sugar molecule containing five carbons |
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Complementary base pairing |
Pairing of nitrogenous base One strand of DNA is opposite of the other Adenine+thymine and guanine+cytosine |
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Nitrogenous base |
Adenine, thymine, guanine, cytosine |
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Nucleotides |
Molecule consisting of a five carbon sugar with a nitrogenous base attached |
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Phosphate group |
Group of four oxygen atoms surrounding a central phosphorous atom found in backbone of DNA |
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Antiparallel |
Describes 2 adjacent nucleotides running 8n opposite directions relative to one another |
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Purine |
Double ring Composed of carbon and nitrogen |
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Pyrimidine |
Single ring Composed of carbon and hydrogen |
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Phosphodiester Bond |
A chemical bond of the kind joining successive sugar molecule in a polynucleotide |
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1 |
Hydrogen bonds |
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2 |
Phosphodiester bonds |
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3 |
Glycosidic bond |
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4 |
Adenine |
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5 |
Thymine |
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6 |
Cytosine |
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7 |
Guanine |
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8 |
Deoxyribos sugar |
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9 |
Phosphate |
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Wilkins and Franklin studied the structure of DNA using? |
X ray diffraction |
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Wilkins and Franklin studied the structure of DNA using? |
X ray diffraction |
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Template |
A single stranded DNa sequence. Acts as guiding pattern to produce a complementary mRNA |
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Semiconservative |
1/2 of parent strand is "conserved" in both new daughter strands |
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DNA helicase |
The enzyme that unwinds double helical DNA |
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Single stranded binding proteins (SSBs) |
A protein that keeps separated strands of DNA apart (prevents annealing) |
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DNA gyrase |
Enzyme that relieves the tension produced by the unwinding of DNA |
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Replication fork |
The region where the enzymes replicating a DNA molecule are bound to untwisted, single stranded DNA |
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Replication bubble |
Where two replication forks are in close proximity to eachother, producing a bubble in replicating DNA |
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Anneal |
Pairing of complementary strands of DNA through hydrogen bonding |
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RNA primer |
A sequence of 10-60 RNA bases that is annealed to a region of single-stranded DNA for the purpose of initating DNA replication |
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Primase |
The enzyme that builds RNA primers |
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Leading strand |
Synthesized continously during DNA replication |
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Lagging strand |
Synthesized in short fragments, which later are joined together |
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Okazaki fragments |
Short fragments of DNA that are a result of the synthesis of the lagging strand |
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DNA polymerase 1 |
An enzyme that removes RNA primers and replaces them with the appropriate deoxyribonucleotide |
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DNA ligase |
Enzyme that joins DNA fragments together |
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DNA polymerase 111 |
Enzyme that connects new bases to the old bases in DNA template |
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DNA polymerase 1 and 111 |
Proofreaders, makes sure there's no mistakes. If mistakes are found, the incorrectly paired nucleotide is removed or excised and the correct one is added. |
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DNA is in the shape of? |
Double helix |
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Nucleotides are made of? |
Sugar, phosphate, and one nitrogen bases |
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Holds nitrogen bases together? |
Hydrogen bonds |
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Sugar found in DNA |
Deoxyribose |
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Sugar in RNA |
Ribose |
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Chargaffs rule? |
Amount of A in DNA is always equal to amount of T |
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Showed photograph to Watson and Crick |
Maurice Wilkins |
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The difference between hydrogen bonds in A+T and G+C |
A+T 2 bonds, C+G 3 bonds |
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Where do free floating nucleotides come from? |
From food we eat |
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Enzyme unravels DNA |
Helicase |
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Enzymes that attaches free floating nicleotides |
DNA polymerase 111+1 |
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Enzyme that connects fragments on lagging strand |
DNA ligase |
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Prevents Annealing |
SSBs |
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Relieves tension on unwound strands |
DNA gyrase |
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RNA that is transcribed from DNA and delivers genetic code to ribosome |
mRNA |
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Twisted ladder structure |
Helix |
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Produced xray to identify DNA structure |
Rosalind Franklin |
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RNA that delivers amino acids to ribosome |
tRNA |
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Process of DNA transferring code to mRNA |
Transcription |
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Terms for sequence of 3 nitrogen bases that form a code |
Codon or triplet |
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Group of three complementary bases on tRNA that pairs with codons on mRNA |
Anticodon |
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3 steps in both transcription and translation |
Intation, Elongation, termination |
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Process of reading mRNA to determine protein structure |
Translation |
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Signals ribosome to attach to mRNA strand |
Promoter region ahead of start codon |
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Ends protein synthesis |
Stop codon |
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Three post transcriptional modifications of mRNA |
5' cap, 3' tail and remove introns |
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Enzyme transcribes mRNA from a DNA template |
RNA polymerase |
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3 results of mutations |
Substitution, Addition, and Deletion |
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Mutation that occurs in the introns of mRNA |
Silent mutation |
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Mutation from result of addition or deletion |
Frameshift mutation |
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Mutation that causes translation to end early |
Nonsense mutation |
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A base substitution that alters a codon and results in the wrong amino acid |
Missense mutation |
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Organelle that is site of protein synthesis |
Ribosome |
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Thymines replacement in RNA |
Uracil |
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mRNA is made during? And where? |
Transcription, in the nucleus |
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DNA is located in? |
Nucleus |
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Process that converts DNA into mRNA |
Transcription |
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Makes up ribosomes |
rRNA |
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Amino acids held together by? |
Peptide bond |
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Transcription takes place in? |
Nucleus |
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tRNA is uses what to match to mRNA? |
Anticodons |
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Proteins made at? |
Ribosome |
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Where does second step of protein synthesis occurs? |
Cytoplasm |
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What attaches amino acids into a chain? |
tRNA |
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tRNA is found in? |
Cytoplasm |
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Exons |
Coding |
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Introns |
Non coding |
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Point mutation |
Only one base is affected |
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Silent mutation |
When nucleotide changes, resulting amino acid is still the same |
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Frameshift mutation |
When base is added or removed |
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Nonsense mutation |
When it's terminated early |
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Missense Mutation |
Substitution and incorrect amino acid is placed |