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12 Cards in this Set
- Front
- Back
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PSA
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Prostate-specific antigen.
Used to screen for prostate carcinoma, but really can be elevated in any prostate pathology (BPH, prostatitis, etc.) |
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Prostatic acid phosphatase
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Prostate carcinoma
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CEA
(2 major, 3 minor) |
Carcinoembryonic antigen
Extremely nonspecific Produced in ~70% of colorectal & pancreatic cancers; also in some gastric, breast, & thyroid medullary carcinomas. Strategy: at diagnosis, check patient's CEA. If elevated, it is likely a tumor marker. Use it later to monitor response to treatment, possibility of mets, or recurrence |
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alpha-fetoprotein (2)
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Hepatocellular carcinomas
Yolk sac tumors (endodermal sinus tumors) - nonseminomatous germ cell tumors of the testes Made by fetus (normally) |
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beta-hCG (3)
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Nice mnemonic - spells HCG! Plus they're all somehow related to pregnancy
Hydatidiform moles Choriocarcinomas Gestational trophoblastic tumors |
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CA-125 (2)
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Ovarian CA, malignant epithelial tumors
VERY non-specific |
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S-100 (3)
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Melanoma
Neural tumors Astrocytomas |
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Alkaline phosphatase
(3 - not all cancers) |
Metastases to bone
Obstructive biliary disease Paget's disease of bone (made from excess bony turnover) |
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Bombesin (3)
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Neuroblastoma
Lung cancer Gastric cancer |
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TRAP
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Tartrate-Resistant Acid Phosphatase
Hairy cell leukemia (B cell proliferation) |
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CA-19-9
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Pancreatic adenocarcinoma
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Calcitonin
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Thyroid medullary carcinoma
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