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22 Cards in this Set
- Front
- Back
What is the ratio of ppl making anti-K if exposed to K antigen?
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1 in 10
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What are some examples of sulfhydryl reagents?
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AET
2ME DTT |
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What does sulfhydryl reagent do to K antigens?
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Destroy
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People with which phenotype are resisitant to some forms of Malaria?
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Fy (a-b-)
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Why are ppl with a certain Duffy phenotype resistant to Malaria?
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because that Duffy ag is a receptor site for the merozoite
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Ppl who are negative for Fya and Fyb are also negative to?
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Fy3
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Which antibodies show dosage?
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Kidd, M, N, U, S, s
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Which antibodies are very weak and difficult to detect, but are very important?
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Kidd
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Higher frequency.
Lua or Lub? |
Lub
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What are mixed field agglutination and in which group does it occur?
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Agglutination with 2 population of cells
Lutheran |
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Lewis antigen are composed of? by?
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water-soluable glycoproteins
tissue cells |
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Which antigens are not part of the red cell membrane and not present at birth?
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Lewis
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What is the most common Lewis phenotype?
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Le(a-b+)
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Comment on the development of Ii ags.
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- i found on cord cells
- i will change to I in 2 years |
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What technique is used to stop anti-I reactions?
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- prewarm plasma and red cells separately and test at 37oC
- use IAT - wash cells by hand with warm saline |
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What happens when there is a reaction to Anti-I?
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Cold hemagglutinin disease
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higher frequency.
P1 or P2? |
P1
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Auto-anti-P causes what disease?
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Paroxysmal cold hemablobinuria (autoimmune hemolytic anemia)
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What is another name for Auto-Anti-P?
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Donath-Landsteiner antibody
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What is special about the reaction of auto-anti-P?
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binds to P positive cells at low temp and causes hemolysis when cells are warmed to 37oC
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MNS system, what are the main ags?
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M, N, S, s, U
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U antigen is inherited when ? and ? is inherited?
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S and s
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