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24 Cards in this Set
- Front
- Back
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How long do RBC’s last from a blood donation? |
42 days at 1-6°c |
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How long do platelets last from a blood donation? |
7 days at 20-24°c |
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How long does plasma last from a blood donation? |
One year at -18°c or greater |
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How long does cryoprecipitate last from a blood donation? |
1 year at -18°c or greater |
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Chromosomes |
Genetic material inherited |
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Chromatin |
A complex of nucleus acid (DNA) wrapped around histones |
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Mitosis |
Two identical daughter cells with the same number of chromosomes (2N) Autosomal |
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Meiosis |
Four gametes having half the number of chromosomes as the parent cell (N) Sex cells |
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Locus |
Location of a gene |
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Gene linkage |
Two genes that are close together and tend to be inherited together. |
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Cis position of genes |
When the genes are on the same chromosome. |
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Trans position of genes |
When the genes are on homologous chromosomes (paired) |
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Genotype |
The sequence of DNA that is inherited |
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Phenotype |
What is produced by the genotype (trait expressed) |
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An amorph |
A “silent” gene that doesn’t produce readily detectable traits. |
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Antigen |
The person being studied in a pedigree chart |
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Humoral response |
Specific antibodies and complement are produced (primary and secondary responded |
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Antigen |
A substance recognized by the body as being foreign which can cause an immune response. |
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Hapten |
A substance 10,000 daltons or less that can’t cause antibody formation on their own but if combined with larger carrier molecules can become immunogenic. |
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Epitope |
The portion of the antigen which the antibody can combine with (responsible for for specificity) |
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Red cell antigens |
Glycoproteins and lipoproteins |
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Glycoprotein Fab |
-Fragment antigen binding site - Light chains (kappa and lands) - Variable |
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Glycoprotein Fc |
- Fragment Crystalline, the area which links the antigen to the effector - Heavy chains, carboxyl, constant - Ig’s (GAMDE) |
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Glycoprotein hinge region |
- Connect the Fab and Fc - Disulfate bonds |
