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10 Cards in this Set
- Front
- Back
what are the side effects of ipecac?
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drowsiness which can mask poison's effect
can delay admin/reduce effectiveness of other treatments eg activated charcoal |
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when is emesis indicated for decontamination?
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not indicated
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when is emesis/gastric lavage ineffective?
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>1hr post ingestion
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what is the mainstay of recommendations for gastric decontamination?
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activated charcoal
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how does activated charcoal work?
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large surface area adsorbs many drugs & poisons
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when is charcoal not useful in poisoning?
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iron, lithium, K+ (no binding)
poor binding EtOH, cyanide nil use in corrosive mineral acids & alkali |
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what is "gut dialysis"?
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repeated doses of oral activated charcoal which may enhance systemic elimination of some drugs
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what is the role of laxatives in poisoning?
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admin of golytely etc (polyethylene glycol electrolyte solution) can enhance decontamination after ingestion of iron tabs, enteric coated meds, illicit drug filled packets & foreign bodies
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once decontamination is done, what are options for further eliminating toxins?
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dialysis (peritoneal or haemo)
urinary alkalisation (eg salicylates) |
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for what drugs is dialysis useful in overdose? (9)
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carbamazepine
ethylene glycol phenobarb metformin salicylate theophylline valproic acid lithium methanol |