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26 Cards in this Set

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Adverse Drug reaction

Other effects aside from therapeutic effect

Primary action

Overdosed; extension of the desired Effect

Types of Adverse effects

Secondary action

Undesired Effects to the pharmacologic effect

Hypersensitivity Reaction

Excessive response to primary or secondary effect of drug

Type of Adverse effect

Anaphylactic Reaction

Involves antibody reacts to SPECIFIC sites in the body.

Cytotoxic reaction

Antibodies that CIRCULATES in the blood attacking antigen.

Serum sickness reaction

cause DAMAGE to various tissue

Delayed allergic reaction

BOUND to specific white blood cell

Rash/hives

Abnormalities in the skin


Discontinue medication

Dermatological Reactions

Stomatitis

Inflammation of mucous membrane


Frequent mouth care

Superinfection

Destruction of the body's normal flora


Fever, diarrhea, vaginal discharge


Administer antifungal

Blood dyscrasia

Bone marrow suppression


Fever, chills, weakness


Monitor boood counts, protective iso.

Liver

Jaundice


Discontinue medication

Kidney

Change in urinary pattern


Notify physician

Poisoning

Damage to multiple system

Hypoglycemia

Low serum blood glucose level


D50

Hyperglycemia

High in serum blood glucose level


Insulin

Hypokalemia

Decrease in serum potassium level


Replace serum

Electrolyte imbalance

Hyperkalemia

High in serum blood potassium level


Ocular toxicity

Visual changes

Auditory damage

Damage to 8th cranial nerve

General central nervous system

Altered level of consciousness

Atropine-level

Urinary retention, blurred vision

Parkinson like

Changes in gait, muscle tremors

Neuroleptic malignant syndrome

Extrapyramidal syndrome

Teratogenicity

May harm developing fetus