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60 Cards in this Set
- Front
- Back
pleiotropy
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One gene, multiple effects.
e.g. Marfan's-- fibrillin defect causes skeletal, cardiac, and opthalmologic effects. Pleo has multiple effects in one person. |
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winged scapula muscle
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serratus anterior
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winged scapula nerve
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long thoracic nerve
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endometritis organism
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Bacteroides
(during a pregnancy you say OI a lot) |
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name the ds DNA viruses
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pox
herpes adeno papillo polyoma hepadna |
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name the ss DNA viruses
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parvo
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name the SS+ RNA viruses
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picorna
calici astro flavi toga corona retrovirus hepE |
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name the SS- RNA viruses
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orthomyxo
paramyxo rhabdo filo borna arena bunya reo delta |
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name the DS RNA viruses
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reo
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name the segmented RNA viruses
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orthomyxo
arena bunya reo |
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esophageal web
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plummer-vinson syndrome
Iron deficiency. Squamous cell carcinoma. (spiders are squishy) |
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myasthenia gravis is associated with this cancer
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thymoma
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infant, with tetany and recurrent Candida infection
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DiGeorge syndrome
= thymic aplasia + no parathyroid |
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palisading necrosiss. most common primary brain tumor in adults.
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glioblastoma multiforme
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red safranin O
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cartilage
mast cell granules mucin "San Francisco-- street carts, ship masts, and muck" |
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a tyrosine kinase is defective in a CD19 positive cells. What's the disease and what's the pattern of genetic transmission?
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Bruton's agammaglobulinemia.
X linked recessive. |
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chemical mediator of aspirin-induced asthma
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leukotrienes
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penicillin induced rash
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hypersensitivity vasculitis
aka leukocytoclasic vasculitis |
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kid with
palpable purpura arthralgia intestinal hemorrhge and pain |
Henoch-Schonlein purpura
IgA complexing. Small vessel vasculitis. Most common childhood vasculitis. |
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Most common head and neck cancer type and location?
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SCC. Tongue or oral cavity.
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erythema with yellowish crust. Most common bugs?
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Staphylococcus aureus.
Group A Strep. |
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DNA repair cancers
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xeroderma pigementosum (eXcision)
HNPCC (mismatch) ataxia-telangiectasia |
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retinoblastoma mutation
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loss of heterogeneity
RB1 |
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brain hemorrhage in preemie born <32 week gestation
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germinal matrix hemorrhage
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asthma is associated with this chemical mediator
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leukotrienes
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most common cause of infetive arthritis
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Neisseria gonorrheae
staphylococcus aureus |
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sever this to stop axillary sweating
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thoracic sympathetic trunk
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chemotherapy agent that causes hearing loss
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cisplatin
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leiomyoma
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aka "Fibroids"
Smooth muscle. [TOT] Most common uterine tumor, especially in black women. Estrogen-sensitive. Benign. [Clinical] Menorrhagia. Tumors change in size (increase in pregancy, decrease in menopause). |
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"birds beak" on barium swallow
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achalasia
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patchy demylination of brain, spinal cords, nerves
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multiple sclerosis
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diabetic patients with foot infections also have this condition
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atherosclerosis, often in femoral artery
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Wegener's granulomatosis
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[Clinical Triad]
Lung / Upper Airway Granulomas (necrotizing). Necrotizing glomerulonephritis. Focal necrotizing vasculititis. [Mech] Autoimmune, small vessel vasculititis. [Findings] c-ANCA. Hematuria. Red cell casts. [Tx] Cyclophosphamide. Corticosteroids. |
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blue sclera
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osteogenesis imperfecta
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most common viral meningitis bug
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enterovirus (in picornaviridae)
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heinz body
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G6PD deficiency
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Li-Fraumeni syndrome
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p53 deletion
Early breast cancer Soft tissue sarcomas. Leukemia + Brain Tumor. |
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walking pneumonia
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Mycoplasma pneumoniae
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hypoglycemia on fasting with no ketone bodies
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acyl-coA dehydrogenase deficiency
(beta-oxidation problem) |
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red shiny tongue
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Megaloblastic anemia due to B12 and/or folate deficiency.
Atrophic filiform papillae. |
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genetic heterogeneity
allelic heterogeneity phenotypic heterogeneity |
genetic heterogeneity-- mutations on different genes cause same phenotype
allelic - mutations in different parts of same allels cause same phenotype phenotypic - mutations on same gene cause different phenotype |
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joint pain, elderly, worse in evenings
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osteoarthritis (age-related)
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Treatment for a man with hepatic impairment, as well as confusion, involuntary hand movements, neuropsychiatric sequelae
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hepatic encephalopathy.
Treat with lactulose, which acidifies GI content. Decreases ammonia content. |
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kid with flank discomfort and mass
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Wilms tumor aka nephroblastma
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nephroblastoma aka
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Wilms turmor
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tissue paper macrophage
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Gaucher's cells.
glucocerbroside accumulation. beta-glucocerbrosidase deficiency. Lysosomal storage deficiency. |
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22q11 Deletition
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DiGeorge
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virchow's node
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L Supraclavicular
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pseudomembranous colitis
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C. dificile
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high urinary uric acid. self-mutilatory behavior (lip biting)
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Lesch-Nyhan Syndrome.
[Mech] X-linked recessive defect in hypoxanthine-guanine phosphoribosyltransfease (HGPRT) Treat with allopurinol. |
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tetracyclines and aminglycosides
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inhibit protein synthesis at 30S
(tetra... 40...30...kinda) |
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erythromycin and chloramphenicol
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50S ribosomal inhibition
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most common post streptococcal glomerolunephritis bug
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Group A Strep (Strep Pyogenes)
Bacitracin sensitive catalase negativce beta-hemolytic |
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epistaxis with fatty infiltration of marrow
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aplastic anemia
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Prader-Willi
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neonatal hypotonia
food seeking freqet temper tntrum diabetes II short stature small hand hypogonadism facies [Mech] Paternal q11 microdeletion OR maternal disomy 15 |
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acanthosis nigricans
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hyperpigmentation due to:
insulin resistance GI cancer Lung cancer |
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clue cell vaginosis
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Gardnerella
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tampon associated toxic shock syndrome
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Staphylococcus aureus
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chocolate cyst
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endometriosis
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Theca-lutein cyst
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