Test 26_Id

Front 1

Howdo you diagnose C. diff colitis?

Back 1

· C difficile toxin! (pcr reaction or enzymeimmunoassay)

Front 2

Describepathogenesis of C diff:

Back 2

· intestinal overgrowth of C diff leads toproduction of toxins: enterotoxin A causes watery diarrhea and cytotoxin Bcauses colonic epithelial cell necrosis and fibrin deposition

Front 3

Describethe clinical manifestations of babesiosis:

Back 3

· asymptomatic to hemolytic anemia associated withjaundice, hemoglobinuria, renal failure, and death!

Front 4

Isrash a feature of babesiosis

Back 4

· NO!

Front 5

Describeclinical features of ehrlichiosis

Back 5

· fever, malaise, headache, nausea, vomiting,(labs show leukopenia and thrombocytopenia but hemolysis and jaundice are notcommon)

Front 6

Howdo you treat cmv esophagitis

Back 6

· Ganciclovir

Front 7

Whatdo you see on biopsy of cmv esophagitis

Back 7

· Intranuclear and intracytoplasmicinclusions (hsv esophagitis showsintranuclear inclusions)

Front 8

Txof herpes simplex esophagitis vs. cmv esophagitis:

Back 8

· acyclovir vs. gancyclovir

Front 9

Whatis a common cause of endocarditis associated with nosocomial utis?

Back 9

· Enterococci, especially enterococcus faecalis(not staph epidermidis; that is with catheters)

Front 10

Islack of current current ART a contraindication to receiving MMR in an adultwith cd4> 200?

Back 10

NO

Front 11

Howcan you distinguish hiv versus mono?

Back 11

· Diarrhea and rash are less common in mono buttonsillar exudate is more common in mono

Front 12

The13-valent pcv13 is recommended for all adults age __ and the 23 one isrecommended ___ months later:

Back 12

65;6-12

Front 13

PPDinduration tx for healthy individuals

Back 13

· 15 mm and over

Front 14

PPDinduration tx for recent immigrants (< 5 years), drug users, residents andemployees of high-risk settings, mycobacteriology lab, diabetes,corticosteroid, leukemia, esrd, malabsorption, or children< 4:

Back 14

· 10 and over mm

Front 15

PPDinduration tx for hiv positive, recent tb contacts, previously healed tb onx-ray, or organ transplant and immunosuppressed people?

Back 15

· 5 and over!

Front 16

Txfor active pulmonary tuberculosis:

Back 16

· 4 drugs for 2 months; then r and I for 4 months(total of 6 months)

Front 17

Txof latent tb:

Back 17

· 9 months of INH or INH for 6 and rifampin for 4months;

Front 18

Whatis typical tx for hep C?

Back 18

· peginterferon and ribavirin with additionalprotease inhibitor for genotype 1 (i.e. telaprevir or boceprevir)

Front 19

Whoare candidates for chronic hep C therapy?

Back 19

· Age > 18, detectable serum hep C virusRNA< compensated liver disease (INR < 1.5, no ascites), other stable labslike cbc, liver biopsy showing chronic hepatitis fibrois,

Front 20

Whatdo you suspect for patient with tick bite, leukopenia, thrombocytopenia,elevated aminotransferases and what do you use to treat?

Back 20

· Ehrlichiosis; doxycycline

Front 21

Erythromycinis good treatment for what two unique things?

Back 21

· Legionnaires and mycoplasma

Front 22

Whatare the four phases of chronic hep B?

Back 22

· immune tolerance, immune clearance, inactivecarrier state, hbE-Ag-negative chronic hepatitis

Front 23

Howdo you followup patient with hep B in immune clearance phase?

Back 23

· Serial alt and hbeAg (need 3 normal alt and 2 or3 normal hbv dna levels over 12 month period to be inactive carrier!)

Front 24

Whatis the preferred hiv screening test:

Back 24

· HIV p23 antigen and antibodies; if positive thendo western blot; then you can do plasma hiv rna testing if really not convincednegative

Front 25

Howdo you treat entamoeba histolytica

Back 25

· ? Metronidazole

Front 26

Didanosinecan cause what?

Back 26

· Pancreatitis

Front 27

Abacavircan cause what

Back 27

· ? Hypersensitivity

Front 28

Nrtican cause what?

Back 28

· Lactic acidosis

Front 29

Nnrtican cause what?

Back 29

· Stevens-johnson syndrome

Front 30

Nevirapinecan cause what?

Back 30

· Liver failure

Front 31

Indinavircan cause what

Back 31

· Crystal-induced nephropathy

Front 32

Whatis Ludwig angina and what is source of infection

Back 32

· Infection of submandibular and sublingual gland;infected tooth is source of infection