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1379 Cards in this Set

  • Front
  • Back
Comminuted fracture
Results in more than 2 bone fragments (vs. simple fracture)
Colles' fracture and cause
Distal radius fracture, usually from falling on outstretched handSmith's fracture
Smith's fracture
Reverse Colles, from falling on dorsum of hand
Jones' fracture
Fracture at base of 5th metatarsal diaphysis
Bennett's fracture
Fracture-dislocation of base of 1st metacarpal w/ disruption of carpometacarpal join
Boxer's fracture
Fracture of metacarpal neck, classically of 5th metacarpal
Monteggia fracture
Fracture of proximal third of ulna with dislocation of radial head
Pott's fracture
Fracture of distal fibula
Which dislocation needs to be reduced on the xray table, and to prevent what?
Hip dislocation, to prevent avascular necrosis
What 2 structures are at risk with a humeral fracture?
Radial nerve
Brachial artery
Chief concern with tibial fractures
Associated compartment syndrome
Pain in the anatomic snuff box indicates
Fracture of scaphoid bone
Contracture of the forearm flexors might indicate
Wokmann's contracture: final sequela of forearm compartment syndrome as fibrous tissue replaces dead muscle
Most common site of compartment syndrome and why
Calf: 4 compartments (anterior, lateral, deep posterior, superficial posterior)
Pain, paresthesia, paralysis after a fracture
Worry about compartment syndrome!
Structures at risk with shoulder dislocation (2)
Axillary nerve and artery
Structures at risk with elbow dislocation (3)
Brachial arter, ulnar nerve, median nerve
Most common cause of hip dislocation
MVA
Structures at risk with hip dislocation (2)
Sciatic nerve, blood supply to femoral head (--> avascular necrosis)
Structures at risk with knee dislocation (5)
Popliteal artery and vein, peroneal nerve, ACL, PCL
Management of knee dislocation
Arteriogram (may need arterial repair) and immediate attempt at relocation (don't want to xray), then ligamentous repair
What is McMurray's sign?
Medial tenderness of knee w/ flexion and internal rotation of knee: indicates medial meniscus tear
Unhappy triad
ACL, MCL, and medial meniscus tear
Test for intact Achilles tendon
Thompson's test: squeeze gastrocnemius; should result in plantar flexion of the foot
What is turf toe?
Hyperextension of great toe due to tear of tendon of flexor hallucis brevis, seen in football players
Another name of exercise-induced anterior compartment syndrome/hypertension
Shin splints
What is a heel spur?
Plantar fasciitis w/ abnormal bone growth in the plantar fascia
What is Marjolin's ulcer?
Squamous cell carcinoma that arises in a chronic sinus from osteomyelitis
DDx of possible bone tumor
1) Mets
2) Primary bone tumor
3) Metabolic disorder (e.g. hyperparathyroidism)
4) Infection
Sclerotic bone reaction in a tumor often indicates
Tumor is benign
Bone tumor with sunburst pattern
Osteosarcoma
Bone tumoor with ground glass lytic lesions
Fibrous dysplasia
Bone tumor with onion skinning
Ewing's sarcoma
How can Ewing's sarcoma mimic the appearance of osteomyelitis?
Bone cysts
Unicameral bone cyst
Fluid-filled cyst in proximal humerus of kids
Presentation and treatment of unicameral bone cyst
Asymptomatic until pathologic fracture

Steroid injections
Aneurysmal bone cyst
Hemorrhagic lesion, locally destructive by expansile growth but doesn't metastasize
Presentation and Rx of aneurysmal bone cyst
Pain and swelling

Curettage and bone grafting
Bouchard's vs. Heberden's nodes
OA

Enlarged PIP vs. DIP joints
Rx for degenerative (OA or post-traumatic) arthritis
NSAIDs only for acute flares, local
Pannus
Inflammatory exudate overlying synovial cells inside the joint
Charcot's joint
Arthritic joint from peripheral neuropathy
What does the Salter-Harris classification describe, and what does it indicate risk of?
Fractures in children involving physis and how much

Potential growth arrest
Rx for congenital hip dislocation
Pavlik harness (maintains hip reduction w/ hips flexed)
Indications for surgery for scoliosis
Respiratory compromise
Rapid progression
Curves >40 degrees
Failure of brace
What is Legg-Calve-Perthes disease?
Idiopathic avascular necrosis of femoral head in kids
What occurs in SCFE?
Migration of proximal femoral epiphysis anteriorly on the metaphysis in kids
What is Blount's disease?
Idiopathic varus bowing of tibia
Varus vs. valgus
Varus is bow-legged
Valgus is knock-kneed
What is Osgood-Schaltter's disease?
Apophysitis of tibial tubercle due to repeated powerful contractions of the quads
Spinal anesthesia is risky in which pts
CAD, low EF, valvular disease, diabetic peripheral neuropathy
What are the risks of spinal anesthesia
Pts who cannot vasoconstrict peripherally or increase CO appropriately: may become hypotension due to the vasodilation caused by spinal anesthesia
How long must aspirin or NSAIDs be d/c prior to surgery
ASA 1 wk
NSAIDs 2 days
(due to how long they effect platelets)
Common preop tests to consider, depending on risks
CBC, chem panel, LFTs, pt/ptt/plts, urinalysis, ECG, CXR
Management of pt found to be anemic before surgery
Postpone surgery and investigate anemia
Fractures with worst prognosis for future growth
Those that extend through the growth plate (can form bony bridges that disrupt later growth)
Nerve possibly injured by transverse humeral fracture
Radial nerve
Injury to radial nerve at wrist would cause
Sensory deficits (only more proximal would affect motor function)
Advantage of open fractures reductions
Shorter period of immobilization
Disadvantages of open fracture reductions (3)
Increased trauma at at fracture site
Infection risk
Delay in bone healing & possible non-union b/c disrupts clots/ hematomas helpful in healing
Dislocation of the radial head w/ fracture of proximal third of the ulna
Monteggia's deformity
Posterior shoulder dislocation may be from
Seizure
Common fracture from falling on outstretched hand
Navicular bone fracture
Pain in anatomic snuff box
Navicular bone fracture
Recovery time for navicular bone fracture
Immobilization of wrist for 16wks-6mo
Osteitis fibrosa cystica is associated with
hyperparathyroidism
Increased bone density is seen in
Oteopetrosis
Another name for Paget's disease
Osteitis deformans
Most common site of osteosarcoma
Distal femur
Rx for osteosarcoma
Combo chemo + surgical resection
Severe bone pain relieved by ASA
Osteoid osteoma
Round-cell type tumor on diaphysis of long bones
Ewing's sarcoma
Nasopharyngeal carcinoma is associated with
EBV
Management of severe facial trauma
Stabilize C-spine, intubate or tracheostomy if needed, CT, nasal packing to control hemorrhage, can delay repair if needed
Rx for SCC of the nasopharynx
Radiation; radial neck dissection if LN mets
Rx for SCC of the oropharynx
Surgery and/or radiation
Rx for SCC of the hypopharynx
Surgery (often + radiation) and radial neck dissection
Pleomorphic salivary gland adenomas
Rubbery, slow growing, potentially malignant, high recurrence, lips/tongue/palate
First branchial cleft fistula opens where and dissection may damage which nerve
External auditory canal
Facial
Second branchial cleft fistula opens where, passes where, and is adjacent to which nerve
Posterolateral pharynx (below tonsillar fossa)
Passes btwn carotid bifurcation
Adjacent to hypoglossal nerve
Painless nodule along lateral border of SCM
Branchial cleft anomaly
Rx for branchial cleft anomalies
Surgical excision
Common complication of tongue cancer (2)
Tongue deviation from involvement of hypoglossal nerve

Decreased sensation from involvement of lingual nerve
Painless swelling in midline of neck that moves with swallowing or tongue protusion
Thryoglossal duct cyst
Course of thyroglossal duct cysts
Retention of epithelial tract between thyroid and its embryo origin at base of tongue
Rx for thryoglossal duct cyst
Surgical resection (often includes hyoid bone) due to risk of infection/ progressive enlargement (and recurrence if only excise)
When does buccal carcinoma usually present and why?
Late (mandibular or amxillary involvement, cervical mets) because of lack of symptoms
3 reasons for postponing surgery
Glucose >250, active infection (cellulitis, PNA, UTI, etc.) diastolic BP >110
Why are beta-blockers not held before surgery?
High rate of rebound HTN if they are
Abstaining from smoking for how long is required to decrease postoperative respiratory morbidity?
6-8wks
Laparoscopy is contraindicated in which pts?
Poor pulm function/ severe COPD pts (b/c it increases CO2 absorption into the blood which requires increased excretion and therefore increased pulmonary work)
5 factors used to predict risk for cardiac complications after vascular surgery
Q waves on ECG
Hx of ventricular ectopy that requires Rx
Hx of angina
DM that requires Rx
>70yo
Most common cause of death after LE revascularization is?
MI
What does Child's classification measure?
Hepatic reserve/ liver function and therefore likelihood of mortality with surgery
What are the 5 parts of Child's classification
Bili, albumin, ascites, encephalopathy, nutrition
Management of an ulcerated hernia
Expedited surgery, as ulcers are often due to pressure necrosis, which increases the risk of rupture and has a mortality rate of 10-40%
What is a cause of oozing blood in a pt with CKD undergoing surgery?
Uremia --> platelet dysfunction
What is the management of platelet dysfunction due to uremia, and what won't help?
Transfusing platelets won't help

Desmopressin, FFP, estrogen, postop hemodialysis
What types of procedures need Abx prophylaxis for pts with high risk cardiac conditions (e.g. prosthetic heart valves)
Dental work, GI or GU surgery, lung surgery
What type of Abx prophylaxis is used?
Amox for dental/ upper respiratory tract procedures

Amp and gent for GI and GU procedures
What complication should be monitored for in pts undergoing a bowel prep?
Dehydration
Management of a breast lump with negative mammography
Still biopsy!
Which histological pattern for DCIS is most concerning for malignancy?
Comedo: up to 30% contain invasive carcinoma
Rx for LCIS
Close observation: mammography every 6mo
Management of sclerosing adenosis vs. atypical ductal hyperplasia
Sclerosing adenosis can usually be observed; ADH should be excised
Management of breast lump in a woman <30yo
Usually ultrasound first (to determine if cystic), then mammogram
Dietary changes for fibrocystic breast disease
Decrease caffeine
Vita E supplement
What is a phyllodes tumor?
Usually a large fibroadenoma (giant cell fibroadenoma) with variable malignant potential and occasional ulceration of overlying skin
Management of bilateral clear discharge
Observation, usually associated with fibrocystic disease or subareolar duct ectasia
Management of unilateral bloody discharge
Surgical biopsy; usually due to intraductal papilloma, but small risk of carcinoma
Metastatic work-up for breast cancer
CXR for lung and bone mets
Liver enzymes
Breast cancer histo subtype with worst prognosis
Inflammatory carcinoma
What is peau d'orange and what does it indicate?
Edema of the skin overlying the mass; tumor invasion of local dermal lymphatics (worse prognosis)
What does a palpable supraclavicular LN indicate?
Stage IV disease with distant mets: unresectable and incurable
Why is a crusted nipple lesion concerning?
Could be Paget's disease of the breast, 95% of which are asociated with an underlying carcinoma
Two arteries that supply the breast
Internal mammary
Lateral thoracic
What distinguishes a modified radical mastectomy?
Spares the pectoralis major
What is a sentinel node?
Node that first receives lymphatic drainage from the tumor
Which patients should not have lumpectomy + radiation?
Those who are not candidates for radiation: CT disease or prior radiation to the chest/ breasts
Contraindications to breast reconstruction
Primary lesions involving the chest wall, extensive local or regional disease, or stage III or IV cancer
Which women with breast cancer need adjuvant chemo?
Tumor >2cm or >Stage 1, especially if ER negative
Which women with breast cancer need neoadjuvant chemo?
Stage III (to shrink tumor before surgery); usually not Stage IV since will only get palliative radiation/chemo
Likely diagnosis of a nodule in the suture line of a women with a history of breast cancer?
Local recurrence
Likely diagnosis of a mammographic abnormality in the contralateral breast of a women with a history of breast cancer?
New primary cancer
Management of elevated LFTs of a women with a history of breast cancer?
Contrast CT to evaluate for liver mets
Management of pathologic fracture?
Orthopedic repair +} postop radiation (controls cancer but doesn't inhibit fracture union)
Likely diagnosis of a coma in a women with a history of breast cancer?
Hypercalcemia (from bony mets and PTHrp)
Likely diagnosis and management of decreased sensation/movement in one leg in a women with a history of breast cancer?
Surgical emergency: may be extradural mets to the spine

Steroids, cord decompression, and radiation
Rx for mastitis
Warm compresses + Abx (staph and strep coverage)
Management of gynecomastia in adolescents
Usually spontaneously regresses
Need to replete every 1ml of EBL with how much isotonic fluid?
3ml
Why do IVF requirements decrease during the recovery period?
Pts begin to mobilize fluid from third space accumulation as they regain GI function
Normal urine output
0.5-1ml/kg/hr
How to distinguish type of postobstructive diuresis (pathologic concentrating defect vs. osmotic diuresis)
Low osmolality: concentrating defect
High osmolality: osmotic diuresis
Postop fever
PNA, URI, UTI, DVT, drug-related, indwelling IVs
Most common cause of postop fever
Atelectasis
Rx for atelectasis
Vigorous pulmonary toilet and incentive spirometry (NOT antibiotics)
What does a fluctuant postop wound indicate, and what is the management?
Fluid collection: remove staples and drain pus; culture fluid and irrigate
Drop of pus on skin at venipuncture exit site
Suppurative phlebitis (infected thrombus in vein and around indwelling cathether)
Rx for suppurative phlebitis
Remove catheter and excise the infected vein + IV Abx
Intestinal contents draining from wound
Small bowel fistula
Causes of small bowel fistula
Leak at jejunostomy insertion site
Breakdown of small bowel anastomosis
Missed enterotomy
Management of small bowel fistula
If signs of peritonitis: operative reexploration

If not, CT to r/o intra-abdominal collection (which would need to be drained), and then monitor drainage + NPO
Factors associated with failure of fistula to heal
Foreign body in wound
Radiation damage to area
Infection or IBD
Epithelialization of fistulous tract
Neoplasm
Distal bowel obstruction
Concern with very high postop fever
Clostridium infection (gas-forming organism: G+, spore forming)
Signs of clostridium infection
Discharge with foul odor/color, crepitus (from gas produced by anaerobes), cellulitis (gas gangrene)
Rx for clostridium infection
High-dose penicillin G + debridement + hyperbaric oxygen therapy + tetanus immunization
Ddx for hemoptysis
Malignancy, bronchitis, PNA, TB, PE
What does "T" indicate on GCS?
Intubated
Goals for CPP and ICP?
<70 and <20
GBM is a tumor of what type of cells?
Glial cells
Which skull fractures require surgery, and when?
Depressed (if >1cm inward) or compound (when bone and overlying skin are broken)
Management of CSF draining from ears/nose
Observe, surgical repair of dura if >14 days
Management of xanthrochromia
4 vessel cerebral angiogram to assess for cerebral aneurysm + Rx to counteract vasospasm + BP control + anticonvulsant therapy
Compression of CNS --> fixed/dilated pupil is usually due to?
Herniation
Rx of Schwannomas
Excision
What is a countrecoup lesion?
Contusion on opposite side of head from injury (as compared to a coup lesion)
Most frequent sites of cerebral contusion
Orbital surface of frontal lobes and anterior portion of temporal lobes
Rx for substantial contusion
Anti-convulsants
Rx for meningiomas
Usually benign
Resection
10% recurrence
Rx for subdural hematoma
Drainage of hematoma thru burr hole; formal craniotomy may be required if fluid reaccumulates
Significant contusions are usually associated with
Loss of consciousness
Excruciating headache, stiff neck, photophobia
Subarachnoid hemorrhage
When is surgery for VSD indicated (3)?
CHF, pulmonary vascular resistance, or if still open at 5yo
Cause of imperforate anus
Failure of descent of urorectal septum
How is imperforate anus distinguished as high or low?
Based on whether rectum ends below or above level of levator ani complex
In females, high imperforate anus often occurs with
Persistent cloaca
Rx for high vs. low and outcomes
Low: perineal operation
High: pull-thru procedure required, lower likelihood of continence
Rx for Hirschsprung's
Colostomy decompression
Cause of jejunoileal atresia
Mesenteric vascular accident during intrauterine growth
Rx for jejunoileal atresia
Resection of primary anastamosis
Most common type of intussusception
Ileocolic
Rx for intussusception
Barium enema, unless has bloody mucous or peritonitis or systemic toxicity: then needs surgery
Rx for annular pancreas
Bypass procedure (duodenoduodenostomy)
Presentation similar to acute appendicitis
Inflamed Meckel's diverticula
When should a Meckel's diverticula be removed?
Only if symptomatic (obstructed, etc.)
Where is a congenital diaphragmatic hernia and what does it cause?
Posterolateral
Respiratory distress from pulmonary hypoplasia
Rx for congenital diaphragmatic hernia
Stabilize pulmonary HTN crisis medically or with extracorporeal membrane oxygenation prior to attempting repair
Initial Rx for hyponatremia
Free water restriction, then hypertonic saline (slowly, if needed)
2 common causes of postop hyponatremia
Stimulation of ADH and excessive water administration in first few days postop
Pts with ileal resection are at risk for what type of kidney stones?
Calcium oxalate (w/o an ileum, unabsorbed fatty acids reach the colon and combine with calcium, leaving oxalate to be absorbed and excreted in the kidney)
Mg deficiency in common in which pts?
Malnourished and large GI fluid losses
Guidelines for prophylactic Abx for colon resections
Single dose <1hr before case (cefazolin), same as always; redose for long cases based on half-life

Bowel prep + oral Abx effective against aerobes and anaerobes as well
Preop cardiac workup for pt with risk factors
EKG + stress test (exercise or, if can't tolerate it, pharmacological)
Hypochloremic, hypokalemic metabolic alkalosis is also known as
Contraction alkalosis
Rx for contraction alkalosis
Volume repletion with NS + K is usually enough to correct the alkalosis
Rx for HIT
Stop heparin, start lepirudin, transition to warfarin when plts >100,000
When do you need a platelet transfusion for HIT?
Never: HIT promotes thrombosis, not hemorrhage
Significant postop bleeding
Presume failed surgical control of blood vessels
When do most periop MIs occur?
3rd post op day when third space fluids return to circulation, increasing preload and O2 demand
Management of acute mesenteric ischemia with and without peritoneal signs
With: emergent XL
Without: angiography, then celiotomy once diagnosis of arterial occlusion or bowel infarction made
Prolonged aPTT likely indicates
von Willebrand's disease
Diagnostic test for von Willebrand's disease
Lack of platelet aggregation with addition of ristocetin
Management of pt with vWD who needs surgery
Transfusion of cryoprecipitate (which provides vWF and increases F VIII)
Management of polycythemia vera pt who needs surgery
Emergent: FFP infusion
Elective: delay until hematocrit/ plts are normalized (can use alkylating agents)
When large amts of banked blood are transfused, pts become deficient in what clotting factors?
V and VIII (as well as platelets)
Postop bowel function: timing for return to normal and initiation of enteral feeding
Small bowel: within hrs
Stomach: within 24 hrs
Colon: 3-4 days
Can institute enteral feeding w/in 24hrs safely
3 electrolyte consequences of refeeding syndrome
Hypokalemia, hypomagnesemia, hypophosphatemia (as electrolytes are shifted back intracellularly)
3 other complications of TPN
Hyperglycemia
Hyperchloremic acidosis
Volume overload --> CHF
Fever, hypotension, lethargy, hypoglycemia, hyperkalemia after steroid taper
Adrenal insufficiency
Rx for adrenal crisis
IV steroids (dexamethasone), volume resuscitation
When should transfusion with FFP be given?
On call to the OR
Factors that predispose to fistula formation and may prevent closure
Foreign body
Radiation
Inflammation
Epithelialization of the tract
Neoplasm
Distal obstruction
Steroids
Fever, chills, hypotension, oliguria, pain at IV site
Hemolytic tranfusion reactions (due to reaction of recipient Abs against transfused antigens)
Management of pt with hemophilia A who needs surgery
If severe disease: e-aminocaproic acid (AMICAR; inhibits fibrinolysis) and desmopressin (DDAVP, increases VIII and vWF)

If mild: DDAVP alone
Why can FFP not be used successfully in hemophiliacs?
Factor levels are too low; need cryo or recombinant factos
NSAIDs can cause ___ dysfunction
Platelet
Potential vitamin deficiency syndromes from gastrectomy and Bilroth II procedure
Megaloblastic anemia (decreased intrinsic factor)
Microcytic anemia (iron deficiency from decreased uptake in duodenum)
Osteoporosis (decreased calcium absorption from duodenum/jejunum)
Steatorrhea (fat malabsorpion)
Diagnostic test for suspected ureteral injury (intraop and postop)
Intraop: methylene blue administration

Postop: CT to see hydronephrosis or fluid collection (urinoma), then IV pyelogram
Tingling sensation and muscle cramps after thyroid surgery
Hypocalcemia, likely short-term due to transient ischemia of parathyroid gland
Rx for symptomatic hypocalcemia
IV calcium infusion (or oral if only mild symptoms); Vitamin D if persistent
Massive transfusion is associated with what electrolyte abnormality?
Hypocalcemia 2/2 chelation with citrate in banked blood
Numbness, Chvostek's sign, and prolonged QT
Hypocalcemia
Best fluid replacement for enteric losses
Ringer's lactate
Rx for hyperkalemia
Kayexalate (to bind it)
Sodium bicarb, dextrose, insulin (all to shift it intracellularly)
Calcium gluconate (to counteract myocardial effects)
Best drainage system and location to minimize wound infections
Closed drainage system that exits skin away from surgical incision
When epithelialization is delayed beyond 3 wks, the incidence of ? increases
Hypertrophic scarring
Ex of epidermal burn
Sunburn
Why are superficial partial thickness burns painful?
Exposed superficial nerves
What leads to healing of superficial partial thickness burns?
Regeneration of epidermis from keratinocytes w/in sweat glands and hair follicles (areas with more will heal more quickly)
Rx for superficial partial thickness burns and why?
Antimicrobial creams and occlusive dressings (epithelialization is faster in a moist environment)
Rx for deep partial thickness wounds
Excise to a viable depth and then skin graft, esp if in cosmetic location since healing is slow and associated with contraction
Rx for full thickness injuries
All should be excised and grafted unless <1cm and no compromise of function, b/c all regenerative elements have been destroyed
When is the best time to graft burns?
Within 5 days of injury to minimize blood loss
Ideal skin covering choice?
Split skin autograft from unburnt areas
Alopecia, poor wound healing, night blindness, anosmia, neuritis, skin rashes
Zinc deficiency
Excessive diarrhea may lead to a ___ deficiency
Zinc
Cardiomyopathy may be due to a ___ deficiency
Selenium
Pts on long-term TPN may develop this deficiency w/ hyperglycemia, peripheral neuropathy, and encephalopathy
Chromium
Potential abnormality following administration of large volumes of normal saline
Non anion-gap metabolic acidosis (due to increased chloride concentrations)
Both LR and NS are both __ (acidic/alkalotic) w/ respect to plasma
Acidic
pH of LR is 6.5
pH of NS is 4.5
Two good situations for NS and for LR
NS: vomiting or significant nasogastric suction losses (b/c pt will have tendency toward metabolic alkalosis)

LR: replacing GI losses and correcting ECF deficits
3 indications for a vena caval filter
- Anticoagulation contraindication/ failure
- Free-floating venous clot
- Chronic PE complicated by pulm HTN
Earliest signs of sepsis
Altered mental status, flushed skin, tachypnea --> respiratory alkalosis
Body's response to stress causes
Increased CO
Hyperglycemia
Peripheral vasodilation
Decreased arteriovenous oxygen difference (from decreased peripheral use of O2)
Rx for hemolytic transfusion reaction
- Fluid resuscitation
- Foley for diagnosis and monitoring of Rx
- Mannitol to induce diuresis (so can clear hemolyzed red cell membranes and avoid renal damage)
- Alkalinization of urine to prevent Hb clumping
Surgery for C. diff colitis
Subtotal colectomy with end ileostomy
Caloric requirements for 70kg man who is:
Nml
Postop
Septic
Multiple trauma/ventilated
Major burn
Nml: 1450
Postop: 1500
Septic: 2000
Multiple trauma/ventilated: 2500
Major burn: 3000
Bleeding from trach
Bleeding from tracheoinnominate artery fistula
Management of tracheoinnominate artery fistula
If still bleeding: stop (inflate balloon or compress)

Once bleeding stopped: fiberoptic exploration in the OR
Criteria for extubation
Negative inspiratory force >-20
Weaned to 5cm H2O PEEP
Minute ventilation <10L/min
RR <20/min
Rapid shallow breathing index btwn 60 and 105
What is the rapid shallow breathing index?
Ratio of RR to tidal volume
Anesthetic not to use in SBO operations and why
Nitrous oxide, b/c is less dense than air so may cause distension of air-filled spaces
Changes in ARDS
Hypoxemia
Decreased compliance
Decreased FRC
Alveolar collapse from leakage of protein-rich fluid
Oxygen dissociation curve shifts (right/left) indicate?
Right: increased tissue oxygen uptake
Left: decreased tissue oxygen uptake
Do the following conditions shift the oxygen dissociation curve R or L?
Acidosis
Increased PaCO2
Increased temp
Increased 2,3-DPG
Chronic lung diseases
Banked blood
All right except banked blood (b/c low in 2,3-DPG)

Chronic lung diseases shift it right via an increase in 2,3-DPG due to chronic hypoxia
Dopamine at low doses
Vasodilation of renal/mesenteric vessels and peripheral vasoconstriction, redirecting blood to kidneys/bowels
Dopamine at high doses
Increases HR, CO, BP and causes peripheral vasoconstriction
Dopamine at all doses
Increases diastolic BP and coronary blood flow
Best pressor choice for cardiogenic shock
Dobutamine (positive inotrope and vasodilates, but minimal chronotropic effect so only mild increase in O2 demand)
Reversal of epidural opiates
IV (not epidural) maloxone
Cardiac index =
CO/BSA
Rx for acalculous cholecystitis
Percutaneous drainage
Hemodynamics in postop septic shock (early)
Increased CO, decreased SVR, normal central pressures
Rx for postop septic shock
Fluids, pressors, Abx (against gram negative rods and anaerobes, esp after bowel surgery), laparotomy and drainage of intraabdominal abscess when identified/ if pt stable
Indications for cholecystectomy in asymptomatic pts
Immunocompromised
Porcelain gallbladder (calcified)
Gallstones >3cm (associated w/ dev't of gallbladder carcinoma)
Why is an intraop cholangiogram often performed in cholecystectomies?
To r/o common bile duct stones
2 major complications of a cholecystectomy
Injury to the common duct (--> chronic biliary strictures, infection, and cirrhosis)
Injury to hepatic artery (--> hepatic ischemia or bile duct ischemia and stricture)
Most common bacteria in cholecystitis
E coli, enterobacter, klebsiella, enterococcus
Antibiotics for cholecystitis
2nd generation cephalosporin preop and for 24hrs postop
When is lap chole indicated in cholecystitis?
Within 48-72hrs
Symptomatic cholelithiasis + elevated bili or elevated LFTs
Suspect common bile duct obstruction
When is removal of common duct stones not necessary?
If they're smaller than 3mm
Management of symptomatic cholelithiasis or gallstone pancreatitis in pregnancy
Pain meds and hydration

If needed, cholecystectomy (ideally in 2nd trimester) or ERCP
Management of cholecystitis + elevated amylase
Cholangiogram (and cholecystectomy) is mandatory with biliary pancreatitis
Cholecystitis + severe symptomatic pancreatitis
Delay cholecystectomy
Ddx for very high fever, gallstones, and hypotensive
Acute cholecystitis, cholangitis, empyema of gall bladder, or pericholecystic abscess
Management of suppurative cholangitis
Emergent ERCP with sphincterotomy, decompression of biliary tree, stone removal
What causes a palpable gallbladder?
Inflamed gallbladder with omentum attached
Management of palpable gallbladder?
Emergent cholecystectomy due to high rupture risk
What is an emphysematous gallbladder?
Air in the wall due to gas-forming organism that has invaded the tissues
Management of emphysematous gallbladder
Urgent surgery
Jaundice, fever, and RUQ pain/tenderness
Acute (or ascending) cholangitis
Management of acute cholangitis
Resuscitation, Abx, US of biliary tree

If obstruction or dilation of CBD seen, then ERCP and biliary decompression
Name for a common duct stone occurring w/in 2yrs of a cholecystectomy
Retained stone
Management of biliary stricture
Surgical exploration and bypass of stricture usually w/ choledochojejunostomy
What two tests should be done in a pt with fever or pain after a lap chole?
Abdominal ultrasound and hepatobiliary nuclide scan (HIDA scan: hepatoiminodiacetic acid) looking for infection or biliary leak
How does the gallbladder look on a HIDA scan in a pt with acute cholecystitis?
Doesn't visualize
Management of postop biliary leak identified on HIDA scan
ERCP to define anatomy

If large collection: biliary drainage w/ temporary stent placed during ERCP
Tender lymph nodes in the groin
Lymphadenitis (or, lower likelihood, malignancy)
Tender testicle (acte vs. gradual)
Acute: torsion of testis
Gradual: viral ochitis or epididymitis
Hernia pt with N/V/abdominal distention
Incarcerated/ strangulated hernia
Hernia pt w/ fever, leukocytosis, and acidosis
Strangulated segment of bowel
Most hernia repairs involve attaching which two structures?
Transversalis fascia to either inguinal ligament or periosteum of pubic ramus
Most common hernia repair type
Lichtenstein repair (prosthetic mesh approximates superior abdominal wall structures to inguinal ligament)
Advtg of mesh?
Avoids creating tension on fascial structures, lessening postop pain and recurrence
Nerves at risk of injury in hernia repair
Genitofemoral, ilioinguinal, iliohypogastric, lateral femoral cutaneous
Pediatric hernias represent a
Persistent patent processus vaginalis, NOT an abdominal wall defect/ defect in floor of inguinal canal
Sliding hernias may involve which other structures herniating?
Bladder, cecum, or sigmoid colon
When are ventral hernias difficult to repair?
Inadequate tissue strength, insufficient tissue, infection, or poor nutrition
Management of a perforated duodenal ulcer
Emergent celiotomy and ulcer closure

If no Hx of PUD, can close ulcer w/ omental patch; if long-standing disease, antrectomy w/ truncal vagotom
Postop postprandial weakness, sweating, lightheadedness, crampy abdominal pain, diarrhea
Dumping syndrome
When should dumping syndrome symptoms abate?
Within 3mo of surgery
Mechanism of omeprazole
Irreversabily inhibits H+/K+ ATPase in gastric parietal cells
Management of ITP w/:
Plts >30,000
Plts <30,000
Active bleeding
Refractory
Observe
Prednisone (+/- IVIG)
Plt transfusion
Splenectomy
Management of appendical adenocarcinoma
R hemicolectomy
Management of achalasia
Calcium channel blockers or long-acting nitrates; endoscopic dilation; Botox injection
Pts with achalasia are at increased risk of
Squamous cell carcinoma
Which symptoms improve in UC pts after total proctocolectom?
Peripheral arthritis, ankylosing spondylitis
Indications for UC surgery
Toxic megacolon, fulminant colitis, high grade dysplasia/carcinioma, definitive management of intractable disease (need end ileostom yas well)
Pancreatic fluid collection 4-6wks after acute pancreatitis
Pancreatic pseudocyst
Rx for pancreatic pseudocyst or pancreatic abscess
Percutaneous catheter drainage w/ Abx
CEA and amylase levels in pancreatic malignancy
High and low
Conditions associated w/ familial autonomous polyposis
Colon cancer
Fundic gland hyperplasia in stomach
Premalignant polyps in duodenum and perampullary region
Extraintestinal malignancies
Retroperitoneal and abdominal wall desmoid tumors
Benign osteomas
Most frequent serious complication of end colostomes
Parastomal herniation
Cause of parastomal herniation
Stoma placed lateral to, rather than thru, rectus muscle
Management of parastomal herniation
If symptomatic, needs operative relocation
Prolapse occurs most frequently w/ what type of colostomy?
Transverse loop colostomy
Management of transverse loop colostomy prolapse
Restoration of intestinal continuity or converstion to end colostomy
Contraindication for pancreatic cancer excision
Involvement of superior mesenteric artery
Management of variceal bleed
Fluisd, octreotide or vasopressin to decrease splanchnic blood flow, beta-blockers for long term prevention
Surgical option for recurrent bleeding varices
TIPS (transjugular intrahepatic portosystemic shunt)
2 classes and 4 types of ulcers
Acid associated (II: body of stomach + duodenum; III: prepyloric)
Not acid associated (I: body or lesser curvature; IV: GE junction)
Surgical indications for ulcers
Hemorrhage, perforation, refractory to medical Rx, inability to r/o malignancy
What surgery is required for ulcers?
Billroth I or II, + vagotomy if ulcer is a Type II or III (i.e. acid-associated)
Billroth I reconstruction
Distal gastrectomy w/ gastroduodenostomy
Billroth II reconstruction
Distal gastrectom w/ gastrojejunostomy
What is a Klatskin tumor?
Cholangiocarcinoma
DDx of biliary obstruction (5)
Pancreatic head cancer, periampullary carcinoma, cholangiocarcinoma, stricture of CBD, CBD stone impacted in ampulla
2 types of pts who often get CBD strictures
Chronic alcoholics w/ chronic pancreatitis

Pts w/ prior biliary surgery
What is a "double duct" sign?
Dilated CBD and pancreatic duct due to narrowing of distal CBD
Option for surgical palliation in pts w/ unresectable pancreatic cancer, and what it helps avoid
Biliary and gastric bypass

Prevents gastric outlet or duodenal obstruction and bile duct obstruction
Dilated intrahepatic ducts (intrahepatic obstruction) but no dilation of the CBD (extrahepatic obstruction)
Cholangiocarcinoma
Where are cholangiocarcinomas located?
At the bifurcation of the hepatic ducts
ERCP or this alternative test can be used to identify the tumor especially if high in the bile duct
Percutaneous transhepatic cholangiography
Rx for cholangiocarcinoma
If primary tumor only, excision (5 yr survival still only 15%)

If unresectable, palliative stenting (5% 5yr survival)

No role for chemo/radiation
Biliary cancer with best cure rate
Ampullary adenocarcinoma
Resection method for ampullary adenocarcinoma
Whipple
Why is lap chole not a suitable option for malignant gallbladder adenocarcinoma?
Need open to remove hepatic tissue (common direct spread to the liver)
Management of calcified (porcelain) gallbladder and why
Chole b/c of 50% association with adenocarcinoma
What test is necessary to ensure not missing other potential diagnoses in a pt with suspected pancreatitis
Obstructive abdominal series (rule out perforated ulcer w/ free air, etc.)
Pancreatitis + severe deterioration and hypotension
Severe necrotizing pancreatitis
Two criteria systems for pancreatitis
Ranson criteria or APACHE II
Pt recovering from percutaneous pancreatic abscess drainage when suddenly becomes hypotensive and drainage becomes bloody
Erosion of cathether or abscess into a major artery (diagnose w/ angiography; control w/ embolization)
Management of elderly pt with suspected pancreatitis
Abdominal CT b/c of concern for other pathologies (mesenteric ischemia and volvulus)
Management of hepatic mets found during colectomy for colon cancer?
Wedge resection
Hernias are defects in what?
Transversalis fascia
Air in biliary tract of nonseptic pt?
Biliary enteric fistula
Complication of biliary enteric fistula
Gallstone ileus (stone into duodenum causes SBO at distal ileum)
Colonic syndrome w/o malignant potential and why not
Peutz-Jeghers (intestinal polyposis and melanin spots on oral mucosa), b/c are hamartomas
Management of gallstone ileus
Ileotomy, removal of stone, cholecystectomy (or interval chole if too inflamed at time of op)
Surgical indications for diverticular disease
Hemorrhage, recurrent diverticulitis, intractable to medical Rx, complicated diverticulitis (perforated +/- abscess and fistula)
Rx for diverticular abscess
Percutaneous drainage then definitive resectional therapy
Rx for perforated diverticulitis
Hartmann's procedure (sigmoid resection w/ end colostomy and rectal stump) or sigmoid resection, anastomosis, and diverting loop ileostomy
Rx for biliary dyskinesia
Cholecystectomy
Rx for gallbladder polyp
<1cm: observe w/ serial US
Suspected carcionma: chole w/ intraop frozen section
Management of acalculous cholecystitis
Abx and perc chole tubes until inflammation has resolved, then lap chole
Appendicitis presentation in the elderly (+anticoag, trauma, or sudden muscular exertion) plus mass on CT
Hematoma of rectus sheath: conservative management
Acute pancreatitis that won't resolve
Pancreatic pseudocyst
Diagnostic test and management of pancreatic pseudocyst
CT

NPO, TPN, observe; if not improved w/in 6wks, cystogastrostomy to drain fluid into GI tract (+biopsy to r/o cancer)
Management of simple hepatic cyst
Observe; if persistently symptomatic, aspiration and then sclerosant or excision
Multilocular cyst in liver w/ calcifications (and management)
Suspect echinoccal cyst from GI parasite: need operative sterilization and excision
Hepatic abscess
IV antibiotics and CT-guided drainage
Amebic hepatic abscess
Metronidazole, no surgery
DDx for solid liver lesion
Hemangioma, focal nodular hyperplasia, hepatic adenoma, mets, HCC
Pts with hepatic adenoma usually have a history of?
OCP use
How to diagnose a hemangioma?
Labeled RBC scan
Indications for surgical removal of benign liver mass
Symptomatic, risk of spontaneous rupture, uncertainty of diagnosis
Why is biopsy not performed when hemangioma or hepatadenoma are suspected but uncertain diagnoses?
High risk of bleeding
Management of hepatic adenoma?
Stop OCPs
Why must persistent or large hepatic adenomas be resected?
Risk of rupture or of development into HCC
When do hepatic adenomas have the highest risk of rupture?
During pregnancy
What is Bowen's disease?
Squamous cell carcinoma in situ
Melanoma location with worst prognosis
Face or trunk
Additional primary melanomas occur in what percentage of pts?
5%
Which melanoma pts need adjuvant therapy, and what does it consist of?
Stage III and IV
Interferon or dacarbazine
Possibly radiation
Management of large macular brown lesion on cheek
Lentigo maligna (Hutchinson freckle): monitor closely, remove if changing b/c is a precursor to lentigo malignant melanoma
Management of subungal melanoma
Biopsy requires excision of portion of nail in continuity w/ lesion; reexcision following diagnosis involves amputation at DIP
Prognosis for anal melanoma
As with other mucosal melanomas, mortality is near 100% at 5 years
Firm, painless mass that is larger than most benign tumors
Sarcoma
Fibrosarcoma and lymphangiosarcoma are associated w/ what two exposures?
Fibrosarcoma: therapeutic radiation

Lymphangiosarcoma: axillary lympadenectomy
Management of suspected sarcoma
Excision biopsy if <3cm
Incisional biopsy if >3cm
NO FNA
Poor prognostic indicators in sarcoma
Mitoses, degree of necrosis, >15cm, symptomatic
Which pts need met workup, what does it consist of, and most common locations for mets
All! (22% have mets at presentation)
CT, MRI, CXR
Liver, lung, bone, brain
Surgical option for sarcoma
Extensive: often total resection of tissue compartment or amputation of extremity
Best adjuvant therapy for sarcoma
Radiation
Management of sarcoma recurrence in the lung
Thoracic wedge resection (one of the whom tumors in which excision of pulmonary mets can result in long-term disease-free survival)

Same with liver mets
7 factors that slow wound healing
Malnutrition
Diabetes
Jaundice
Uremia
Steroids
Chemo
Smoking
Why can pts not do heavy lifting for 6wks postop?
Collagen production and cross-linking are still occurring, so not yet at full tensile strength, prone to injury/disruption
Hard knot-like structure underneath surgical wound
Likely a suture knot: should resolve if was absorbable suture, otherwise can be removed under local anesthesia once wound is fully healed
What is healing by third intention?
Delayed primary closure
Erythema and some pus drainage around wound 3mo postop
Stitch abscess
Management of a stitch abscess
Explore opening w/ hemostat and remove suture under local anesthesia
Management of postop ventral hernia thru wound
Surgery
How long should a wound be observed for before considering revision for its appearance?
6mo
Management of hypertrophic scar
Steroid injections and local pressure dressings

Revision usually not appropriate as are likely to recur
Raised hypertrophic scar that is spreading outside immediate area of incision
Keloid (same as treatment for hypertrophic)
Management of wound infection
Drainage and debridement; usually don't require Abx (only if cellulitis spreading despite drainage)
2 types of wounds that heal by secondary intention
Wounds that are intentionally left open

Wounds that become infected and require opening in immediate postop period
What is the process of a graft revascularizing from granulation tissue called?
Inosculation
What is the advantage of split thickness skin grafts for wounds?
Reduce wound contraction by 60%
Disadvantage of skin grafts
More susceptible to trauma than normal skin
What is required for the skin graft to attach successfully?
Bacterial count on granulation bed must be <10^5 bacteria/gram of tissue
Four categories of wounds
Clean, clean-contaminated, contaminated, infected
Management of contaminated wound
Leave open to heal by secondary infection, treat with saline-soaked gauze
Definition of a clean wound
No entry made into GI, respiratory, or GU tracts and no active infection
Definition of clean-contaminated wound
There is entry into GI, resp, or GU tract but it is prepared both mechanically and antibacterially (e.g. bowel prep before surgery)
Need for prophylactic Abx for clean, clean-contaminated, and contaminated
Clean: none
Clean-contaminated: single preop and postop dose
4 situations in which prophy Abx are indicated
Exposure to bacteria
Prosthetic material
Immunosuppression
Poor bloody supply
When should prophy Abx be given?
1 hr preop
Postop: multiply half-life of drug by 1-2.5
Prophy Abx of choice
Amox (or amp if IV)
Pen-allergic: clinda or cephalexin (or cefazolin if IV)
Rx for amebic liver abscess
Metronidazole
Rx for pyogenic liver abscess
Perc drainage + Abx against G- and anaerobes
Best diagnostic test to determine treatment for sliding hiatal hernia?
Flexible endoscopy to look for esophagitis
1st test when extrahepatic biliary obstruction is suspected?
EUS
Increased SGOT and SGPT indicate
Hepatocellular disease
Increased alk phos indicates
Biliary obstruction
Obese/hirsute man with painful fluctuant mass btwn gluteal clefts
Infected pilonidal cyst
Hematochezia, fever, abd pain
Ischemic colitis
Management of ischemic colitis vs. acute mesenteric ischemia
Expectant (IVF, bowel rest, supportive) vs. surgery
Pts who undergo major colon resections undergo what change in their bowel habits?
None, usually; lots of reserve capacity for water absorption
Pts who undergo major colon resections undergo what change in their bowel habits?
None, usually; lots of reserve capacity for water absorption
Work-up of rectal cancer
Rigid proctoscopy (to assess distance of lesion from anal verge); barium enema or colonoscopy to r/o other lesions; CT abd/pelvis for mets; MRI for extent of local invasion; endorectal US for depth of invasion
Where are most dietary carbs absorbed?
Duodenum (even in short gut syndrome is in residual jejunum)

All of milk except fat absorbed in duodenum
Rx for hepatic adenomas <4cm vs. >4cm
OCP cessation vs. surgical resection b/c of risk of rupture/hemorrhage
Management of acute hemorrhage from L-sided portal HTN (gastric varices + splenic or portal vein thrombosis w/o cirrhosis)
Splenectomy
Management of hepatic focal nodular hyperplasia
Nothing
Acute appendicitis presentation but w/ terminal ileum edema/fibrinopurulent exudate in OR
Regional enteritis; in kids, just do appy
Management of iatrogenic injury of CBD --> biliary stricture
End-to-side choledochojejunostomy (Roux-en-Y) performed over a stent
Acute intestinal radiation injury is manifested by
Diarrhea or GI bleeding
Chronic intestinal radiation injury causes ___ and can lead to these clinical problems
Progressive vasculitis and fibrosis

Malabsorption, ulceration, fistulization, or perforation
4 things that inhibit intestinal motility
Sympathetics: drugs, hormones, emotions (fear)
Gastrin
Factor that stimulates intestinal motility
Parasyms: acetylcholine
Best test for diagnosis of gastrinoma
Secretin stimulation test
Another name for gastrinoma
Zollinger-Ellison syndrome
Most common location of a gastrinoma
"Gastrinoma triangle" : duodenum, junction of neck/body and pancreas, and junction of cystic and common bile duct
Expected fluid/electrolyte status in SBO
Dehydration from vomiting and poor oral intake

Contraction alkalosis with hypokalemia (due to loss of H+, Na+, and Cl-)
Concern with SBO and heme-positive stool in rectum
Obstructing tumor or ischemic bowel
Management of SBO due to inguinal hernia
Urgent repair and relief of bowel obstruction due to risk of strangulation
Most common tumor that metastasizes to the intestine
Melanoma
Indications for surgical exploration with SBO
Localized abdominal tenderness, fever, tachy, leukocytosis, metabolic acidosis (high risk for strangulation)
2 operative management choices for pt with SBO with uncertain bowel viability
Resect and anastamose
OR
Second look operation 24hrs later
Greatest risk associated w/ enterotomy
Postop leak and development of small bowel fistula
3 causes of abdominal distention other than SBO
Ileus, air swallowing, constipation
Diagnostic tests for suspected ischemic bowel
Sigmoidoscopy
Mesenteric angiogram (to determine whether candidate for surgical revascularization)
Long-term medical Rx after surgical revascularization
ASA
Management if full-thickness necrosis found on sigmoidoscopy
Exploration and resection (vs. mucosal ischemia only, can observe closely)
Long-term management of pt with necrosis from ligament of Treitz to transverse colon
Can resect, esp in younger pt, but will have short bowel syndrome and need chronic TPN/ small bowel transplant
Most common location for Crohn's
Ileocolic
Thickened bowel wall with fibrous strictures and deep fissures
Crohn's
Epithelial ulceration and crypt abscesses
UC
Noncaseating granulomas or mesenteric lmphadenopathy can both indicate this type of IBD
Crohn's
Focal aphthous ulcers can indicate this type of IBD
Crohn's (whereas general ulceration is usually UC)
What is the "string sign" and what does it indicate?
Narrowing of terminal ileum from edema: Crohn's
Rx for acute disease vs. prevention in UC
Steroids for acute
5-aminosalicylic acid for prevention of relapse
Drug for perianal Crohn's
Metronidazole
Problems associated w/ resection of the terminal ileum
Poor reabsorption of bile acids and vita B12 --> diarrhea, malabsorption, oxalate stones, B12 deficiency
Rx for Crohn's disease of the rectum
Can use 5-acetylsalicylic acid
Screening recommendations for UC of pancolitis vs. L-colon only
Colonoscopy every 1-2yrs beginning after 8yrs of disease vs. after 10yrs of disease
Why are random biopsies during colonoscopy necessary in UC?
Colon cancer of UC doesn't always follow sequence of polyp --> cancer
Fever, blood-tinged diarrhea, and pain on defecation after a total proctocolectomy w/ ileal pouch- anal anastamosis
Pouchitis
Rx for pouchitis
Metronidazole
Pt with UC, abdominal pain, distention, fever, and bloody diarrhea
Worry about toxic megacolon
Diagnostic test for toxic megacolon
Abdominal series (v. dilated colon w/ mucosal edema and w/o signs of abscess or perforation); often also a CT to r/o abscess or perf
Rx for toxic megacolon
If stable: NGT, NPO, TPN, IVF, broad spectrum Abx, high-dose IV steroids
Suspected toxic megacolon + free air on upright CXR
Perforation! Immediate OR
Air in wall of colon on XR
Impending perforation, likely OR!
PEX manuever that must always be done when appendicitis is suspected?
Rectal exam to detect pain in the right pelvis from retrocecal appendicitis
Appendicitis like presentation + dysuria/urinary WBCs
Possibly uncomplicated UTI, but also possibly appendiceal abscess in continuity w/ bladder
Abd pain + urinary RBCs too numerous to count
Severe UTI or kidney stone
Pregnant woman with RUQ pain
Worry about appendicits (appendix has been shifted)
Surgical management of perforated appendicitis w/ localized abscess
Appy + incise, drain, and irrigaet abscess; leave closed drain in abscess draining to outside; close muscle but leave skin open
Suspected appendicitis with small yellow firm mass at TIP of appendix
Carcinoid tumor (if not spread, just needs routine appy)
Suspected appendicitis with larger yellow firm mass at BASE of appendix
Needs excision; if >2cm or at base, suggestive of malignancy and indication for R colectomy
Diagnostic tests needed after carcinoid tumor diagnosed on path
Baseline urinary 5-hydroxyindoleacetic acid (5-HIAA) and serum serotonin level (carcinoid determinants of malignancy involve mostly biological behavior of tumor)
Management of postop pelvic abscess
Drain w/ perc catheter if possible, other open surgical drainage (or transrectal/ transvaginal drainage)
Colonoscopy screening for pts with first degree relative w/ CRC or adenomatous polyp?
Starts at 40yo (or 10yrs prior to relative's diagnosis?)
Colonoscopy screening for pts with FH of FAP?
Genetic counseling, yearly flex sig

Colectomy once polyps discovered
Colonoscopy screening for pts with FH of HNPCC?
Genetic testing and colonoscopy every 1-2yrs beginning at age 20yo, yearly beginning at 40yo
Colonoscopy screening for pts w/ Hx of large or multiple adenomatous polyps that were remoevd?
Colonoscopy 3yrs after removal
Colonoscopy screening for pts with Hx of CRC
Colonoscopy 1yr after initial op, screening at 3yrs and then 5yr intervals
CEA measurement indications after CRC
Every 2-3mo for 2yrs (detects 80% of recurernces)
Surgical management for external vs. internal hemorrhoids
External: excision
Internal: excision or banding
Any hemorrhoids w/ bleeding need what?
Colonoscopy to r/o colon cancer
2 types of polyps
Pedunculated (on a stalk)
Sessile (flush w/ mucosa)
F/u after polypectomy
Repeat colonoscopy after 3-6mo to ensure sucessful removal and then surveillance colonoscopy every 3yrs
Management of carcinoma in head sv. stalk of pedunculated polyp
Head: polypectomy only
Stalk (esp if margin <2cm, poorly differentiated, or vascular/lymphatic invasion): may require bowel resection in addition to polypectomy
Staging studies for colon cancer
CXR
CEA
LFTs
Most common presenting symptoms of R or L-sided colon cancer
Pain/mass
Most common presenting symptoms of sigmoid colon cancer
Pain or bowel complaints
Most common presenting symptoms of rectal cancer
Bowel complaints or bleeding
Prep before bowel surgery (3 parts)
- Bowel prep (polyethylene glycol or mag citrate)
- Oral nonabsorbed Abx (to decrease colonic bacteria)
- Single preop dose of 2nd generation cephalosporin (to decrease wound infections)
Specific places to explore for colon cancer mets
Small bowel mesentery, peritoneal surface, diaphragm, liver
Postop management after colon cancer surgery
NPO w/ IVF until bowel function returns; d/c when tolerating food
Colon cancer prognosis worse for these types of tumors (4)
Mucus-producing
Signet ring cell tumors
Tumors p/w bowel perf
Tumors w/ venous or perineural invasion
What types of adjuvant chemo are used in colon cancer pts and for what stage?
Stage III
5-FU and leucovorin or levamisole
Screening f/u after colon cancer
Repeat colonoscopy at 6mo then 12mo intervals + frequent monitoring of CXR, CEA, and LFTs
Management of colon cancer + large liver lesion
Large liver lesions shouldn't be resected at tmie of surgery
Feculent vomiting postop from colectomy ddx (2)
Leakaeg from anastomosis --> persistent ileus

Mechanical obstruction
Cause of feculent material draining from inferior wound
Anastomotic leak that is spontaneously draining to skin; should close with NPO and IVF; need CT scan to determine if there is undrained collection
Diagnosis and management of distended colon
Likely sigmoid or cecal volvulus

Proctosigmoidoscopy first to eval for/hopefully treat sigmoid volvulus; if negative, emergent celiotomy for presumed cecal volvulus (risk of rupture in 1-2hrs)
Common additional site of liver cysts
Lung
2 equivalent management options for echinococcal liver infections
Surgical drainage

Albendazole/mebendazole + perc drainage
2 causes of feculent vomiting after colectomy
- Leakage from anastomosis --> persistent ileus
- Mechanical obstruction due to adhesions, hernia, or obstructed anastamosis
Management of feculent material draining from inferior aspect of colostomy wound
Likely due to anastomotic leak

NPO, IVF, usually will self-close
Pt 6mo s/p colostomy for colon cancer returning w abd pain, constipation, small stools
Concern for anastomotic recurrence of cancer or stricture at anastomosis
Rectal carcinomas spread to which lymphatic nodes?
Internal iliac
Sacral
Inferior mesenteric
Inguinal (if <5cm from anal verge)
Type of resection necessary for rectal cancer >5cm above anal verge vs. <5cm
>5cm, can do anterior resection

<5cm, need abdominoperineal resection due to margins including sphincter
Which rectal cancers require postop chemo?
Stage III (regional LNs) or high-risk stage II
Which rectal cancer pts receive preop radiation?
Those with large/bulky tumors
2 alternatives to colostomy for rectal carcinoma
Sphincter-preserving proctectomy or local resection
Pelvic pain after rectal cancer
Early postop: operative nerve injury or infection

Later: need to r/o local recurrence w/ CT pelvis
Which hepatic mets are unresectable?
Multiple lesiosn in both lobes, lesions intimate w/ vascular structures or invading local structures, or lesions in cirrhotic livers
Most common cause of anal cancer and presenting symptoms
SCC
Bleeding, drainage, pain, pruritis
Where does anal cancer metastasize to?
Inguinal LNs (also superior rectal LNs)
Staging w/u for anal cancer
CT and transrectal US
3 treatment regimens for anal cancer depending on location of lesion:
- Superficial, small, mobile
- Large w/o extension or LNs
- + LNs
- Local excision alone
- Nigro protocol: chemo (5-FU, mitomycin C) and radiation, then resection only if there's biopsy-proven residual cancer
- Chemoradiation, then radical resection
Pain med to be avoided in diverticulitis
Morphine (b/c increases intracolonic pressure)
Management of 2nd episode of diverticulitis
Elective resection 4-6wks after inflammation has resolved (b/c risk of significant complication (perf, abscess) increases w/ each recurrence)
What is required before surgery for diverticulitis?
Preop or intraop colonoscopy to identify region w/ diverticula
Diverticulitis w/ patient deteriorating
Free perforation or intra-abdominal abscess
Eval for suspected perf/abscess from diverticulitis
CT
Management of diverticulitis abscess
CT-guided needle insertion of catheter in collection
What is Ogilvie syndrome?
Pseudo-obstruction: massive cecal and colonic dilation in absence of mechanical obstruction
Management of Ogilvie syndrome?
D/c narcotics/ anticholinergics; endoscopic colonic decompression if dilation >10cm; surgery if perforation or ischemia suspected
Cause of Zenker's diverticulum
Premature contraction of cricopharyngeal muscle on swallowing --> partial obstruction
Symptoms of Zenker's
Dysphagia, regurgitation, recurrent aspiration PNA
Diagnosis and treatment of Zenker's
Barium swallow
Diverticulectomy w/ cricopharyngeal myotomy
RUQ pain, jaundice, GI bleeding
Quincke triad for hemobilia
Causes of hemobilia
Iatrogenic (from percutaneous liver procedures), anticoagulation, gallstones, parasitic infection, neoplasm
Diagnosis and treatment of hemobilia
Angiography/ endoscopy
Angiographic embolization if intrahepatic
Surgery if bleeding from extrahepatic bile ducts or gallbladder
Noncaseating granulomas are associated with this type of IBD
Crohn's
IBD w/ crypt abscess
UC
Sensation of voided air with urination
Pneumaturia, e.g. from colovesical fistula
Most common type of fistula due to diverticulitis
Colovesical fistula
Most common cause of rapid lower GI bleeding
Bleeding diverticula and vascular ectasias
Rx for vascular ectasia
Coagulation w/ monopolar current
Why are diverticula associated w/ bleeding?
Underlying vasa recta artery penetrating thru bowel wall
How to diagnose an ongoing GI bleed w/ negative upper and lower scopes
Technetium-labeled RBC scan or mesenteric angiography
When to use angiography vs.RCN scanning
Angiography in less stable pts
RBC scanning in more stable pts, can detect slower bleeds
2 treatment options for bleeding discovered during angiography
Vasopressin into the vessel
Embolization
Typical pt/ causes of sigmoid volvulus
Debilitated pts from nursing homes due to chronic laxative use, chronic illness, or dementia
Type of obstruction in sigmoid volvulus
Closed loop obstruction
Rx for sigmoid volvulus
Rigid proctosigmoidoscopy and placement of rectal tube
Definitive Rx for sigmoid volvulus
Sigmoid colectomy w/ colostomy or anastomosis
Rx for cecal volvulus
Urgent surgical treatment w/ detorsion alone, cecopexy, or right colectomy
3 treatment options for Ogilvie's syndrome w/ colon diameter >11-12cm (otherwise conservative Rx)
1) Endoscopic decompression
2) Neostigmine (increases colonic tone and counteracts dilation)
3) Surgical decompression
Rx for rectal prolapse
Internal: high fiber diet
External w/ bleeding: surgery
3 surgical options for prolapse
1) Rectopexy (no removal)
2) Transabdominal rectosigmoid resection
3) Perineal approach w/ removal and anastamosis
Rx for anal fissures (conservative vs. more invasive)
Bulk agents/ softeners, sitz baths

If deep and chronic, lateral sphincterotomy +/- biopsy if suspicious for cancer
What are anal fissures and what causes them?
Tears in the anoderm (--> painful BM, tenderness on palpation, blood on TP) due to repeated trauma from hard stools or IBD
Pain and drainage in sacrococcygeal area
Pilonidal abscess (infection in hair-containing sinus in sacrococcyx)
Rx for pilonidal abscesses
Unroof, remove all hair, leave open to heal by secondary intention
Most common complications of stomas
#1: leakage around the bag
Also parastomal herniation, bowel obstruction abscess, fistula formation
What is a Hartmann pouch?
If distal bowel is closed and not brought to abdominal wall but rather dropped back into pelvis
Common indication for Hartmann pouch
Diverticulitis when bowel can't be safeul reconnected
Small intestine bleeding in a pt under 30
Meckel's diverticulum
Work-up for suspected Meckel's?
99m-Tc pertechnate scan
What type of tumor is a carcinoid tumor?
Apudoma
Congenital cystic dilation of the extrahepatic biliary duct?
Choledochal cyst
Management of choledochal cyst?
Complete resection of cyst (due to risk of malignant changes) and roux-en-y choledochojejunostomy
What is stress ulceration?
Acute gastric or duodenal erosive lesions following shock, sepsis, major surgery, trauma, or burns
Cause of stress ulceration?
NOT increased acid; may be ischemic damage to mucosa; often ulcers are in multiple places
Treatment of pancreatic pseudocyst?
Wait 6wks to allow for spontaneous resolution; then excise, externally drain, or internally drain into GI tract
Do pancreatic pseudocysts have malignant potential?
No, b/c have no epithelial lining
Complications of pseudocysts
Gastric outlet and extrahepatic biliary obstruction

Spontaneous rupture and hemorrhage
What is a Diuelafoy's lesion?
Abnormally large submucosal artery that protrudes thru small, solitary mucosal defect 6cm distal to GEJ --> spontaneous bleeding
Rx for Diuelafoy's lesion?
Endoscopic
When is hemicolectomy needed for appendiceal carcinoid tumors?
If >2cm
Asthma, right heart valvular disease, flushing, hepatomegaly, diarrhea
Carcinoid syndrome
Indication for resection of a gallbladder polypoid lesion?
Clinical symptoms
Electrolyte abnormalities after pancreatectomy
Hypocalcemia
Hypophosphatemia
Iron deficiency
Pernicious anemia
Characteristics of cecal diverticula?
Congenital
Solitary
True diverticula (involve all layers of bowel wall)
Management of liver hemangiomas?
Can usually observe; affected by hormones, but usually only hemorrhage iatrogenically (from attempted biopsy)
CEA is elevated in these pts w/o cancer
Smokers
High CEA indicates?
High likelihood liver involvement/ peritoneal spread
Management of Mallory Weiss tear?
If bleeding stopped: expectant
To control bleeding: balloon tamponade, endoscopic control, gastrostomy/oversewing, or vasopressin (but not in CAD pts)
Types of gastric ulcers and which are acid-associated?
I (lesser curvature)
II (gastric and duodenal)
III (pyloric)
IV (juxtracardial)
II and III are acid associated
Rx for Type I ulcer
Antrectomy (+/- vagotomy)
Surgical Rx for type III ulcer?
Vagotomy and antrectomy
Surgical Rx for toxic megacolon?
Subtotal colectomy with end ileostomy
Rx for SCC of the anus refractory to Nigro protocol (chemo and XRT)?
Abdominal-perineal resection w/ permanent end colostomy
Rx for proximal and midrectal cancers?
Low anterior resection
Radiolucency under right hemidiaphragm indicates?
Pneumoperitoneum
Causes of pneumoperitoneum
Perforated diverticulum, perforated gastric ulcer, perforated transverse colon carcinoma, or strangulated hernia w/ necrotic bowel
Intestines in upside down U
Sigmoid volvulus
How does PEEP improve oxygenation?
Increasing FRC b ykeeping alveoli open at end of expiration
Potential negative effects of increased PEEP (3)
- Alveolar overdistention --> pneumothoraces
- Decreased venous return/CO
- Increased minute ventilation requirements due to increased dead space ventilation
Systemic hypotension, JVD, distant heart sounds
Beck's triad for cardiac tamponade
What is pulsus paradoxus?
Decrease in SBP by >10 at end of inspiration
Risk factors for eriop MI
Previous infarction, esp w/in 6mo
DOE
Age >70
MR
> 5 PVCs/min
Tortuous or calcified aorta
When should you not use epi w/ lidocaine?
Tissues supplied by end arteries (fingers/ toes, ears, nose, penis)
What can interfere with measurement of wedge pressure w/ Swan Ganz catheter?
PEEP or CPAP
Increased risk of periop stroke with?
History of stroke
What is the mortality from periop stroke?
High
PaCO2 levels are a reliable indicator of?
Adequacy of alveolar ventilation
Respiratory acidosis from hypercarbia
Alveolar hypoventilation
Hypoxemia with increased PCO2 is NOT
PE, pulmonary edema, PNA, or atelectasis (b/c those pts should be hyperventilating (decreased CO2) to improve oxygenation
Benefits of albumin vs. transferrin/acute phase reactants to eval nutritional status
Long life life (3 wks) vs. short (hrs), but not affected by intravascular volume
The physiologic goal of shivering is to ___, which causes ___
Generate heat to maintain core temp

Increases metabolism by 3-5x, which increases O2 consumption/ CO2 production, which is usually counterproductive in critically ill pts
What should be administered preop in a pt with vWD?
Cryoprecipitate (provides both FVIII and vWF)
Best choice for stress ulcer prophylaxis
Sucralfate (better than antacids, which cause loss of acidic protection and G- overgrowth)
Procedure for tracheostomy
Skin incision below cricoid cartilage, strap muscles spared and retracted, thyroid isthmus divided if necessary, trachea entered at second tracheal ring
Rx for malignant hyperthermia
(3)
Cessation of anesthesia, hyperventilation w/ 100% O2, IV dantrolene
Effect of PE on CVP
Increases by causing RV overload and increasing RAP
Renal failure with eosinophilia
Cholesterol atheroembolism
Hyperkalemia, hyponatremia, hypoglycemia, fever, weight loss, dehydration
Adrenocortical insufficiency (e.g. Addison's disease)
Why are antacids given before emergency intubation?
Risk of intubation, esp if don't know gastric contents
Rx for necrotizing fasciitis
Wide debridement
Passive rewarming is appropriate for which pts?
Mild hypothermia (between 34 and 36C)
Smoke inhalational injuries: cause, which lab value is elevated, mortality
Epithelial injury from chemical irritation

Carboxyhemoglobin

Low in absence of cutaneous burns
Which anesthetic can cause seizures?
Enflurane
Adjunct anesthetic that can cause hypotension if given in bolus
Morphine
Anesthetic with nephrotoxicity
Methoxyflurane
Complications of halothane
Hypotension, decreased CO
Anesthetic that can cause increased distension if used in a pt with bowel obstruction
Nitrous oxide
Hypertensive pt after carotid endarterectomy is at risk for ___, so needs this treatment and monitoring
- Hemorrhagic stroke
- Aggressive BP management with nitroglycerin or nitroprusside
- Arterial cath for beat to beat monitoring of BP
Indications for intracranial pressure monitoring (5)
Subarachnoid hemorrhage, hydrocephalus, postcraniotomy status, Reye's syndrome, blunt head trauma w/ repeated surgeries
A thrombin time measures the function of what?
Fibrinogen
Which nerve innervates the majority of the intrinsic hand muscles?
Ulnar nerve
Which nerve innervates the extensor muscle (and one other function)?
Radial nerve (also does forearm supination w/ musculocutaneous nerve)
Which inflammatory mediator is key to wound healing?
Monocytes (phagocystose + secrete GFs)
When in healing to fibroblasts appear?
Day 3
Which type of collagen predominates during proliferative phase of wound healing, and what is it replaced with?
Type III
Type I
Lympangitic inflammatory streaking along extremities indicates infection with what type of bacteria, and what Abx are indicated?
Strep
Penicillin
Cutaneous ulcers associated with IBD?
Pyoderma gangrenosum
Rx for pyoderma gangrenosum
Systemic steroids and immunosuppressants (e.g. cyclosporine)
Rx for frostbite (initial rewarming and overall)
Rapid warming in hot water (40-44C)

Elevation, Abx, tetanus toxoid, debridement of necrotic skin
What are clean surgical wounds?
No part of respiratory, GI, or GU tract entered
3 causes of squamous cell carcinoma
Sun exposure, chronic ulcers or sinus tracts (draining osteomyelitis), history of radiation or thermal injury
Advantage/disadvantage of Mohs surgery
Improved cosmetic result, but longer time required (small increments with immediate frozen section analysis); no difference in outcomes
Where do the superficial and deep finger flexors insert and which has a common muscle belly?
Superficial: middle phalanx
Deep: distal phalanx; common muscle belly (so only superficial flexors can move finger when others are immobilized)
Healing a tendon injury requries formation of a ___, requiring a balance between ____?
Tenoma, which tends to become adherent to surrounding sheath; need balance btwn avoiding adhesions w/ early mobilization and risk of rupturing unhealed tendon
Tendon repair of the hand is most difficult in which area?
Fibroosseous tunnels
When should devitalized tissue be excised in cases of severe burns?
Early, except w/ deep wounds of palms, soles, genitals, and face

Staged excision of deep partial-thickness or full thickness burns btwn 3 and 7 days after injury
Topical therapy used for burns to delay colonization?
Silver sulfadiazine
Why can skin autograft not be placed over eschar?
Requires a vascular bed
When should longitudinal escharotomy be performed?
First sign of vascular compromise
Rare complication of silver nitrate
Methemoglobinemia
More common complication of silver nitrate
Hyponatremia and other electrolyte imbalances
Main complication with silver sulfadiazine
Neutropenia
Main complication with mafenide acetate
Metabolic acidosis 2/2 inhibition of carbonic anhydrase
Where is SCC of the lip usually found?
Lower lip (b/c of sun exposure)
When are early carpal tunnel syndromes often noticed?
Nocturnally
When does carpal tunnel often present in women?
During pregnancy, w/ recurrent symptoms during PMS in subsequent periods
What is responsible for wound contracture?
Fibroblasts with actin microfilaments
Initial Rx for leukoplakia
Oral hygiene, avoidance of alcohol/tobacco, avoidance of chronic irritation (e.g. ensuring dentures fit properly)
When does leukoplakia need biopsy?
Thick lesions
When are cleft lips/palates repaired?
Lip in first 3mo of life
Palate at 12-18mo
What is a Marjolin's ulcer?
SCC that develops in a chronic wound such as a previous burn scar or sinus tract 2/2 osteo
Rx for Marjolin's ulcer
Surgical excision or amputation
What is the cause of compartment syndrome for burn pts?
Increased pressure 2/2 tissue edema and lack of elasticity of burnt skin (eschar)
Rx for compartment syndrome due to burns
Escharotomies of affected extremity
Which wounds should not be closed?
- Dirty or contaminated (e.g. animal bites)
- Trauma by puncture/gunshot or crush injury)
- Older than 6hrs
What prophylactic Abx should be used for bowel cases?
3rd generation cephalosporin (for G- coverage)

Clinda or metronidazole for anaerobic coverage
Ulcer over medial malleolus, painless, and associated w/ brawny induration
Venous stasis ulcer
Most common location for diabetic ulcers
Plantar surface of foot
Most common location for ischemic ulcers
Dorsum of foot or 1st/5th toe
Rx for acute diaphragmatic rupture
Emergent ex lap
What is a seatbelt sign and how is it managed?
Abdominal wall ecchymosis from seatbelt

Observe for signs of enteric or mesenteric injury even if pt stables/tests negative
When should you tape the chest for rib fracture and why?
Never! (compounds problem of inadequate ventilation)
Management for lower rib fractures
Imaging to assess for associated abd injuries, pain control, admit if respiratory probelms, will heal spontaneously
Organ most likely to be daamged in blunt abd trauma
Spleen
Rx for venous injury in hemodynamically unstable pts
Ligation, not repair (only repair if HDS, is a proximal vein, and there is also an arterial injury)
Rx for signs of arterial insufficiency w/ signs of neuro compromise in extremity (Ps)
Immediate op and repair
Eval for penetrating trauma below nipples
Diagnostic peritoneal lavage
Why is local wound exploration contraindicated in penetrating trauma to the chest?
Risk of creating pneumothorax
Insulin secretion in trauma pts is?
Increased
Rx for complete common bile duct transection
T-tube
W/ loss of tissue, choledochojejunostomy or cholecystojejunostomy
Abd trauma w/ pain, RUQ mass, obstructive symptoms, and coiled spring appearance of duodenum
Duodenal hematoma
Rx for duodenal hematoma
NGT and observe
Rx for closed radial nerve palsy
Fracture reduction and observation, 90% will self resolve
First sign of increased ICP
Change in level of consciousness
Initial Rx for increased ICP w/ hypotension
Hyperventilation (mannitol or head elevation may exacerbation hypotension)
What is flail chest?
Paradoxical respiratory movement due to at least 2 fractures in each of 3 adjacent ribs
Rx for flail chest
Analgesia, chest physiotherapy

Mechanical ventilation only if respiratory compromise develops
High carboxyhemoglobin levels indicate
Carbon monoxide poisoning
Rx for carbon monoxide poisoning (mild vs. severe) and for how long?
Mild: 100% O2
Severe (coma, respiratory failure): Hyperbaric chamber

Either should last until carboxyhemoglobin levels are <10%
Rx for single pelvic fracture in pelvic ring
Bed rest until HDS, then gentle ambulation
How does fluid resuscitation for electrical injury compare to that for thermal injury?
Can't use BSA b/c often deep tissue damage is worse than superficial; need massive amts of fluid
Electrical pts require f/u with what specialists?
Ophthalmologists (b/c of risk of cataract development)
Highest rate of vascular injury comes with this MSK injury
Knee dislocations (due to extreme force required to dislocate the joint)
Indications for thoracotomy after chest tube placement?
1500ml of blood on initial chest tube placement
OR
Persistent bleeding at 200mL/hr for 4hrs or 100 mL/hr for 8hrs
With subQ emphysema in the extremities, worry about
Necrotizing fasciitis
Rx for suspected clostridium infection
High dose penicillin G
Rx for myocardial contusion with normal ECG
Tele for 24hrs, no need for ICU, low risk of complications
Cellular changes during injury/sepsis (4)
- Gluconeogenesis
- Acute phase protein synthesis (fibrinogen, completement, haptoglobin, ferritin)
- Decreased glutamine (is consumed)
- Increased urinary nitrogen loss and peripheral release of aas (from accelerated protein breakdown)
Diagnostic test for suspected penetrating injury to rectum
Sigmoidoscopy
Why is barium contraindicated in suspected penetrating injury to colon, and what should be used instead?
Spillage of barium mixed with feces into peritoneal cavity would increase likelihood of intraabdominal abscess

Water-soluble medium
Rx for postop bile leak
ERCP with sphincterotomy and/or tenting
When is a bile leak a biliary fistula?
If drains >50cc/day for over 2 wks
When is a bile leak major, and what mangement does that warrant?
Early biliary drainage >300cc/day

Re-laparotomy and hepatico-jejunostomy
What cannot be excluded following vascular trauma w/ ischemic changes despite palpable pulses?
Arterial injury
When do blowout orbital fractures require immediate operative intervention (4)?
- Extraocular muscle entrapment (e.g. inability to move eye in particular direction)
- Fracture >50% of orbital floor
- Diplopia
- Enophthalmos >2mm
Management of blunt renal trauma?
Nonsurgical:
- Bedrest to decrease likelihood of secondary hemorrhage
- Abx to reduce likelihood of infection w/in hematoma
If urethral injury is suspected, what should be done prior to placing a Foley?
Retrograde urethrogram
Management of pt with urethral injury who cannot receive a Foley cath?
Suprapubic cath
3 complications of pancreatic injury
Fistula, pseudocyst, abscess
Most common cause of death in pts with pancreatic injury
Exsanguination from associated injury to major vascular structures
Management of penetrating pancreatic injur
Most just need simple drainage
How does a pneumatic antishock garment work?
Elevates BP by increasing peripheral vascular resistance
How should a pneumatic antishock garment be discontinued?
Very slowly to prevent sudden irreversible hypotension
Indications for ER thoracotomy
- Release cardiac tamponade in pts deteriorating radpily
- Cross-clamping of descending in aorta if can't maintain BP otherwise
- Internal cardiac massage for pts w/ faint pulses/distant heart sounds and other resuscitation unsuccessful
Rx for enterocutaneous fistulas
Bowel rest, TPN, correct electrolyte abnormalities
Complications of enterocutaneous fistulas
Fluid and electrolyte depletion, skin necrosis, malnutrition
Imaging study for pt with enterocutaneous fistula
Small-bowel follow through to determine location, relation to other organs, and whether there is distal obstruction
Which enterocutaneous fistulas are least likely to close?
Proximal small bowel fistulas (up to mi-ileum) w/ high output of fluid
Choice for repair of artery
End-to-end anastamosis if possible
If too much lost, use a vein graft
Contraindications for nonoperative management of a splenic injury (2)
Indication of associated injury requiring operation (e.g. peritonitis)

Hemodynamically unstable pt or deteriorating
4 criteria through which DPL can be positive (diagnostic peritoneal lavage)
>10cc gross blood initially
>100,000 RBC/ uL
> 500 WBC / uL
Elevated amylase, bili, or alk phos
CXR indications of thoracic aortic injury
Widening of mediastinum
Loss of aortic knob
Sternal or scapular fracture
Multiple L rib fractures
Massive L hemothorax
PEX difference in pts in neurogenic vs. hypovolemic shock
Neurogenic: pts are warm and pink and usually bradycardic
Hypovolemic: pts are cold and clammy and usually tachycardic
Abdominal compartment syndrome causes (5)
- Increased ICP/ decreased CPP (Due to decreased venous return)
- Decreased venous return/CO
- Increased SVR
- Increased peak airway pressures
- Decreased RBF/GFR and liver function
Rx for laryngeal obstruction
Cricothyroidotomy
Rx for pericardial tamponade
Subxiphoid, supradiaphragmatic incision and creation of pericardial window
Rx for an open pneumothorax
Occlusive dressing over defect; later thoracostomy tube (preferably thru separate incision) and formal closure of chest wall
Which cells produce TNF?
Monocytes/macrophages (present in G-shock and sepsis)
Paucity of bile ducts on liver bipsy years after transplant indicate
Chronic rejection
Rx for chronic liver rejection
Retransplantation
Rx for portal venous thrombosis early after transplant
XL and thrombectomy
Sequela of hepatic arterial thrombosis
Biliary strictures 2/2 ischemia
What is combined in a transplant cross match?
Donor lymphocytes w/ recipient serum
What is a cross match searching for, and why would those things be present?
Recipient Abs against donor HLA antigens

Not naturally present but acquired from pregnancy, blood transfusion, or prior transplant
What does a positive cross match predict?
Transplantation will cause a hyperacute rejection
Shortly after receiving chemo, pt becomes febrile w/ hyperkalemia, hyperphosphatemia, and hypocalcemia
Tumor lysis syndrome
Which cells mediate tumor lysis syndrome?
Cytotoxic T cells
How does cyclosporine work?
Inhibits IL-2 production, so there is no expansion of cytotoxic T cells or production of antibodies
Conservative measures for renal failure pts not yet in need of emergent dialysis
<60g of protein/day
Limit fluids
Kayexylate for hyperkalemia
Best transplant matches
Living relative with 6 HLA matches > living relative with 0 HLA matches > cadaveric transplant
Most common cause of death within 1yr of cardiac transplant
Infection
Most common cause of death after 1yr of cardiac transplant
Accelerated graft arteriosclerosis
Presentation of hyperacute renal rejection
Swollen bluish oliguria
Histology of hyperacute renal rejection
Fibrin; platelet thrombosis; necrosis of glomerular tufts, renal arterioles, and small arteries
Rx for hyperacute renal rejection
Plasmapheresis and cyclophosphamide decrease antibody load, but no definitive treatment available
Main toxicity of cyclosporine
Nephrotoxicity
Matching criteria for cardiac transplants
Size and ABO compatability (cannot tissue-type like with renal transplants, b/c can only be protected by hypothermia for 4hr)
Increased Cr, decreased UOP, fever, tenderness 2mo after renal transplant
Acute rejection (1wk-3mo posttransplant)
Rx for acute renal rejection
Biopsy to confirm diagnosis, high dose steroids, anti-T-cell antibody (e.g. OKT3)
4 most common post-transplant viruses
CMV, EBV, VZV, Herpes viruses
CMV infection can cause
Ulceration and hemorrhage in GI tract
Pneumonitis, retinitis, encephalitis, pancreatitis
Best and worst survival rate after liver transplant is for which pts?
Best: cholestatic liver disease
Worst: fulminant hepatic failure
Rx for GVHD
More aggressive immunosuppression
Glucose and end-organ outcomes after pancreas transplant for T1DM
Normal serum glocuse and normal GTT

No reversal of diabetic retinopathy or reduction in ulcers/amputations

Can prevent recurrence of nephropathy if combo w/ kidney transplant
How long should presence of an extrahepatic malignancy defer liver transplant for?
2yrs after curative therapy
Contraindication to liver transplant
Alcohol use w/in 3mo
What is OKT3?
Monoclonal Ab against CD3 antigen complex on mature T cells
Severe complications of OKT3 (4)
Noncardiogenic pulmonary edema
Encephalopathy
Aseptic meningitis
Nephrotoxicity
What is OKT3 used for (3)?
Rejection prophylaxis, acute rejection, induction therapy
Diagnostic test for enlarged cervical LNs
FNA (or open biopsy if lymphoma is suggested)
When should adjuvant chemo be started?
10-14 days after surgery, to allow for wound healing (unless there are compelling clinical indications for more urgent treatment)
Extravasation of chemo agents during IV administration may cause what?
Severe ulceration and sloughing
What can normalize wound healing when given with methotrexate?
Folinic acid
For which 4 tumor types is histologic grade closely correlated with stage/ prognosis?
Soft tissue sarcoma, transitional cell cancer of the bladder, astrocytoma, chondrosarcoma
Wilms tumor is associated with what 4 conditions and how often?
Aniridia, cryptorchidism, hemihypertrophy, hypospadias
10%
Most common presentation of Wilms tumor
Asymptomatic mass (hematuria in less than half, hypertensive in just over half)
MEN 1 tumors
Pituitary, pancreatic, parathyroid
MEN 2A tumors
Hyperparathyroidism, pheochromocytoma, medullary thryoid cancer
MEN 2B tumors
Pheochromocytoma and mucosal neuromas, medullary thyroid cancer, gangliomas
Most common GI site for non Hodgkin's lymphoma?
Stomach
What are interferons?
Glycoproteins; products of virus-infected cells that inhibit viral replication
3 diseases that interferons are very effective in
Burkitt's lymphoma
Hairy cell leukemias (and other hematologic malignancies)
Hep B and C
Typical procedure for parotid carcinoma
Superficial parotidectomy w/ facial nerve preservation (may need deeper/loss of nerve if tumor is more involved) + regional node dissection (50% rate of occult mets)
Most common operative complication of chemotherapy?
Perirectal abscess
This condition carries an increased risk of testicular cancer
Cryptorchidism (even after surgical correction)
Procedure for testicular cancer
Inguinal orchiectomy + LN dissection if embryonal or teratoma
Why don't seminomas need LN dissection?
Very radiosensitive
Why don't choriocarcinomas need LN dissection
Very chemosensitive, often w/ pulm mets
Pheos are associated with these 4 syndromes
MEN 2A, MEN 2B, VHL, NF-1
What causes tissue death from radiation?
Both direct effect of xrays and indirect effect mediated by free radicals
Which cells are resistant to radiation?
Those deficient in oxygen
Cells in which phase of the cell cycle are most sensitive to radiation?
M phase
IL-2 is an effective drug for pts with which two metastatic diseases?
Metastatic melanoma and metastatic RCC
Complications of IL-2 treatment
Lymphocytosis, eosinophilia, fluid retention, fever, decrease in peripheral vascular resistance (is like septic shock)
Nitrates and nitrosamides are associated with what kind of cancer?
Stomach cancer
Excessive amts of dietary fat and fiber deficiency is associated with what kind of cancer?
Colorectal cancer (and pancreas, prostate, and uterine)
3 elements of the mainstay of immunosuppression for cardiac and renal transplants
Steroids
Calcineurin inhibitors (FK506 or cyclosporine)
Antimitotic agents (azthioprine or mycophenylate mofetil)
Should needles be capped or uncapped for HIV pts?
Always uncapped! Capping procedures are more dangerous
RET protooncogene is associated w?
MEN 2
PTEN tumor suppressor gene is associated w/?
Cowden disease (multiple harmartoma syndrome)
p16 tumor suppressor gene is associated w/?
Malignant melanoma
Which tumors are more likly to be ER+, BRCA1 associated or BRCA2?
BRCA 2
Which other cancers are associated with BRCA1?
Colon and prostate
Which other cancers are associated with BRCA2?
Gallbladder, bile duct, pancreatic, gastric, melanoma, prostate
Toxicity associated w/ cyclophosphamide
Hemorrhagic cystitis
Toxicity associated w/ bleomycin
Pulmonary fibrosis
Toxicity associated w/ vincristine
Peripheral and central neurotoxicity
Toxicity associated w/ cisplatin
Oto/neuro/nephrotoxicity
Toxicity associated w/ 5-FU
Mucositis, dermatitis, cerebellar dysfunction
4 posttransplant malignancy and the viruses associated with them?
Posttransplant lymphoproliferative disorder (enlarged LNs): EBV
HCC: HBV or HCV
Kaposi's sarcoma: HHV8
Cervical cancer: HPV
Rx for posttransplant lymphoproliferative disorder
Withdraw immunosuppression, antivirals, chemo, or monoclonal Abs
What is tertiary hyperparathyroidism?
Persistent hypercalcemia 2/2 autonomous parathyroid function after renal transplant (high calcium pre and posttransplant)
What is a Dukes C colon cancer?
AKA Stage III, indicates involves adjacent LNs
Mild increase in creatinine shortly after renal transplant likely indicates?
Nephrotoxicity from cyclosporine, hold it
Low WBC count after renal transplant likely indicates?
Bone marrow toxicity from azathioprine, hold it
Rx for renal transplant pt with CMV
High dose gancyclovir
Elevated Cr 3-6mo after transplant with vs. without fever and graft tenderness and Rx
With: likely rejection, start steroid burst and/or OKT3
Without: likely cyclosporine toxicity, hold it
Rx for adrenal insufficiency
Exogenous steroids
Preop Rx for Addison's disease
Exogenous steroids
Best test for adrenal insufficiency?
ACTH stimulation test
Difference between adenoma and carcinoma on thyroid scan
High uptake (hot) for adenoma
Low uptake (cold) for carcinoma
Swelling under incision, stridor, difficulty breathing after thyroidectomy and Rx
Wound hematoma: intubation, explore wound, evacuate hematoma, control bleeding
True or false: previous history of therapeutic radiation to breast is an absolutely contraindication to lumpectomy with XRT
True
Rx for inflammatory breast cancer
Surgery, chemo, and XRT
3 Rx options for prolactinomas
Asymptomatic: observe
Symptomatic: dopamine agents (e.g. bromocriptine)
Refractory symptoms: surgery
What is sestamibi scanning for?
Parathyroid problems
Labs in primary hyperparathyroidism (2 most imp for diagnosis)
Increased PTH with increased serum calcium
Hypercalcemia with low urinary calcium
Familial hypocalciuric hypercalcemia (vs. in primary hyperparathyroidism, urinary calcium should be high or nml)
Usual Rx for glucagonoma
Distal pancreatectomy
Rx for hyperglycemia in unresectable glucagonoma pts
Octreotide
When do adrenal adenomas need to be resected?
If they are functioning, nonfunctioning but >6m, or carcinoma suspected
Rx after adrenal surgery
Steroid replacement for 6-12mo postop, even if contralateral adrenal is normal
Radiation-induced thyroid cancer is usually what histo type?
Papillary
Rx for radiation-induced thyroid cancer
Near total or total thyroidectomy due to high incidence of bilateralityand more effective use of radioactive iodine postop
What % of pts with radiation history and thyroid nodule have cancer?
40%
Risk of invasive breast cancer after LCIS: what type, what location, and for how long?
Most commonly ductal carcinoma

Risk equivalent in both breasts, last indefinitely, not correlated to amt of LCIS
Whorled pattern in breast mass on young girl?
Fibroadenoma
Work up for incidentally identified adrenal tumor (e.g. small incidentaloma) (4 things and what each is ruling out)
- Dexamethasone suppression test (to r/o Cushing's)
- 24hr urine collection to r/o pheo
- Serum lytes and plasma renin/aldosterone to r/o aldosteronoma
- MRI to r/o malignancy
First therapy for hypercalcemia
Vigorous hydration to restore intrasvascular volume --> renal perfusion and increased urinary calcium excretion
What diuretics should be used in hypercalcemia?
Loop diurectics (Lasix); thiazides are contraindicated b/c cause pts to become hypercalcemic
Indications for surgery for asymptomatic primary hyperparathyroidism
<45yo
Markedly increased urine Ca
Kidney stones
Decreased Cr clearance
Marked hypercalcemia
Decreased bone mass
Two causes of fat necrosis in the breast
Trauma
Prolonged pressure
Fat necrosis is often confused with?
Breast cancer (although it doesn't increase the risk of carcinoma)
Diagnosis and treatment of fat necrosis
Excisional biopsy, once confirmed, then excision
45yo woman with HTN, hair development, and 7cm suprarenal
Functional adrenocortical tumor (functional indicates can secrete cortisol, androgens, estrogen, aldosterone, or multiple hormones)
What is Cushing's disease?
Pituitary tumor --> hypercortisolism --> bilateral adrenal hyperplasia
Rx for functional adrenocortical tumor
Resection
Adjuvant therapy for unresectable functional adrenocortical tumor
Mitotane
Preop treatment for pheo
Alpha blockade 1-3wks in advance (+ volume expansion)
Then add beta blockade (not alone b/c of risk of CV collapse)
True or false: chemotherapy is contraindicated during pregnancy
False; only during first trimester, is generally safe during second and third trimesters
Nipple erosion and eczema
Paget's disease of the breast
Paget's disease with a mass
Likely an infiltrating ductal carcinoma
Rx for Paget's disease
Modified radical mastectomy (possibly less if no associated mass?)
Paradoxical rise in serum gastrin and IV secretin is diagnostic of what syndrome?
Zollinger Ellison syndrome
Rx for Zolllinger-Ellison syndrome
Distal pancreatectomy (where the gastrinoma mass usually is)
Which drugs are useful in Zollinger Ellison syndrome?
H2 blockers
Preop treatment before thyroidectomy for Graves disease to prevent postop thyroid storm
Medicate to euthyroid
10 days of Lugol's iodide solution, propylthiouracil, or methimazole
Rx for thyroid storm
Beta blockade (e.g. propanolol)
Rx for primary hyperparathyroidism
Resection of usually solitary adenoma
Rx for parathyroid hyperplasia
Resection of 3 1/2 parathyroid glands; leave the rest and can reexplore if needed
Calcium and possibly Vita D supplementation afterward
Rx for cystosarcoma phyllodes
Wde excision with adequate margins
What is Hurtle cell cancer and how does it usually behave?
Type of follicular thyroid cancer; often multifocal and bilateral, more likely to metastasize, higher mortality
Rx for Hurthle cell lesions?
Lobectomy if unilateral adenoma
Total thyroidectomy for carcinoma
What test is not useful for Hurthle cell cancer and why?
FNA, b/c can't determine invasion
Amyloid deposits in the stroma of a thyroid tumor indicate?
Medullary carcinoma
Rx for follicular thyroid mass
Adenoma: lobectomy
Carcinoma or >4cm: total thyroidectomy
12 signs of Cushing's syndrome
Truncal obesity
HTN
Hirsutism
Moon facies
Proximal muscle wasting
Ecchymoses
Skin striae
Osteoporosis
DM
Amenorrhea
Growth retardation
Immunosuppression
What percent of gastrinomas/insulinomas are malignant?
50%/10%
What antibiotic is useful in unresectable malignant insulinoma?
Streptozotocin (controls symptoms by selectively destroying islet cells)
How do the characteristics of positive lymph nodes change the staging of breast cancer
Palpable lodes are only Stage II unless they are fixed or matted, then Stage III
What is desmoplasia/ a desmoplastic reaction?
Growth of fibrous or connective tissue, secondary to another insult (e.g. scar formation around a neoplasm or adhesions after abdominal surgery)
Rx for sclerosing adenosis
Nothing: is a benign lesion
Rx for LCIS
Twice yearly exams and yearly mammography; is not a precancerous lesion in itself, just predicts future risk of cancer but equal in both breasts
Which subtype of DCIS has the highest recurrence?
Comedo
Rx for stress urinary incontinence
Estrogen, pelvic floor exercises, timed voiding, or urethral sling surgery
Rx for urge incontinence
Anticholinergics, biofeedback, timed voiding
Cause of overflow incontinence
Bladder outlet obstruction
Cause and Rx for total incontinence (continuous leakage of urine)
Fistula
Surgery
Hypospadias in the scrotal area is associated with these 2 other problems
Bilateral undescended testes
Infertility
Where is hypospadias most commonly
Corona
Hypospadias in the corona is often associated with a?
Chordee (ventral curvature of penis)
Why would a pt not have hematuria with a kidney stone?
If completely occluding lumen of ureter
What % of kidney stones recur
50% within 5-10yrs
Initial Rx for kidney stones
Hydration and analgesics
Pathophys of testicular torsion
Abnormally narrowed testicular mesentery w/ tunica vaginalis surrounding testis and epididymis in bell clapper deformity
Testicular pain decreased w/ elevation
Prehn sign for epididymitis
Rx for testicular torsion
Bilateral orchiopexy
Which renal tumor can only be diagnosed on patho?
Oncocytoma
3 types of benign kidney lesions
Simple cysts, angiomyolipomas, oncocytomas
Rx for RCCs based on size
<4cm: partial nephrectomy
>4cm: radial nephrectomy (includes ipsilateral adernal gland and perirenal fat)
How does prostate cancer spread?
Direct extension, lymphatics, blood vessels
Most common site of distant mets from prostate cancer?
Axial skeleton with osteoblastic bony lesions
Rx for prostate cancer with T1 masses in men >65yo?
Expectant management
Where in the gland does prostate cancer usually initiate?
Periphery
Risk factors for prostate cancer
FH, African American, diet
Surgical indications for BPH
Urinary retention refractory to medical Rx, upper tract dilation, renal insufficiency 2/2 outflow obstruction, bladder stones, recurrent UTIs
Rx for BPH
TURP
Postop problem with TURP
Hyponatremia due to hemodilution 2/2 absorption of irrigation fluid
Management of suspected ruptured urethra
Retrograde urethrogram
If complete disruption: suprapubic cath, delay repair 4-6mo (after which hematoma will be resolved)
Rx for ureteral injury
Reconstruction (primary anastamosis vs. ureteroplasty)
Rx for ureteral injury if can't do immediate repair
Placement of stent w/ catheter into proximal ureteral stump and delayed reconstruction
Which kidney stones require further workup?
>1cm (if <.5cm, likely to pass spontaneous): IV pyelogram

If high-grade obstruction, need nephrostomy or passage of ureteral stent
Rx for cryptoorchidism
Inguinal orchiopexy before 1yo
To which LNs do seminomas usually metastasize?
Along regional lymhatic drainage pathways to iliac, aortic, and renal LNs
Rx for seminoma
Removal of affected testis
Sample LN (usually external iliacs) for mets; if present, radiation
Best postop assessment of sigmoid viability?
Sigmoidoscopy
Repeated cellulitis in pt with unilateral LE swelling is due to?
Unilateral primary lymphedema
Pt s/p AAA repair now w/ severe L flank pain and bloody mucus per rectum
Ischemic colitis due to damage to IMA
Smokers often have isolated atherosclerosis in which LE artery?
Superficial femoral
Diabetics often have isolated atherosclerosis in which LE artery?
Tibioperoneal
Inability to dorsiflex toes may indicate
Anterior compartment syndrome
Acute arterial occlusion w/o collaterla inflow and rapid reperfusion of ischemic muscle may cause
Anterior compartment syndrome
Rx for claudication
Smoking cessation, weight loss, exercise; vasodilators don't help
How long is aspirin's antiplatelet effect?
7-10days
Mechanism of aspirin
Inhibits synthesis of thromboxane A2 and subsequent production of prostaglandins
Pt with angina and claudication who is now light-headed on exertion especially when working with his arms may have?
Subclavian steal syndrome
What is the subclavian steal syndrome?
Atherosclerotic occlusion of subclavian artery proximal to vertebral artery so that when involved arm (usually left) exercises, becomes relatively ischemia, causing reversal of flow thru the vertebral artery --> diminished flow to the brain
Rx for subclavian steal syndrome
Carotid-subclavian bypass or subclavian-carotid transposition (or dilation/stenting of artery)
Aortoiliac atherosclerotic occlusive disease causes what symptom?
Claudication of buttock and thigh
Bilateral stenosis or occlusion of what arteries can cause sexual impotence?
Hypogastric (internal iliac) arteries
Best predictor of periop ischemic cardiac eevnts for peripheral vascular surgery
Dipyridamole-thallium imaging (pts often can't undergo stress test)
Management of acute graft occlusion is with what med?
Urokinase (fewer allergic rxns than streptokinase)
% effectiveness of urokinase and reocclusion rate %
75% effective
20% reoccluded w/in 1yr (even if angioplasty or anastamotic revision performed; 50% w/o surgical revision)
Rx for symptomatic popliteal aneurysm
Exclusion (ligation) and surgical bypass; can also terat asymptomatic pts if good surgical candidates
Cause of popliteal aneurysms and what else to look for
Atherosclerosis
Often bilateral and/or associated with extrapopliteal aneurysms
Abdominal pain out of proportion to PEX?
Intestinal ischemia
Increased serum lactate may be associated with what arterial pathology?
Mesenteric ischemic
Management of pt with AAA and horshoe kidney
Preop arteriogram to define the likely unusual vascular anatomy

Retroperitoneal dissection and implantation of all renal arteries
Immunocompromised pt with new murmur, fever, back pain, and enlarged saccular abdominal aorta below renal arteries
Mycotic aortic aneurysm
What is the cause of mycotic aortic aneurysms?
Infection w/ staph or salmonella
Rx for infrarenal mycotic aortic aneurysm
Axillofemoral bypass, excision of invovled aorta, grafting, Abx for 3-6mo
Best surgical option for rest claudication in otherwise healthy patient
Aortoefmoral bypass
Best surgical option for rest claudication in pt with many comorbidities
Extraanatomic bypass (femorofemoral or axillofemoral bypass)
Contraindication to femorofemoral bypass?
Bilateral iliac artery disease
Rx for empyema
Thoracotomy with decortication (to allow lung to reexpand) and antibiotics
Facial swelling and cyanosis on bending over
Superior vena cava syndrome
Top 2 causes of SVC syndrome
Bronchogenic carcinoma
Lymphoma
Rx for SVC syndrome
Diuresis
Radiation and chemo for malignancy
Rx for perforation of esophagus during endoscopy for pts w/ and w/o underlying esophageal problem
Without: thoracotomy w/ primary repair and drainage of mediastinum

With: thoracotomy with esophagectomy
Rx for lung abscess
Prolonged Abx; if fails, percutaneous or surgical drainage
Rx for descending aortic dissection
Reduction in change in BP over change in time (dP/dT): beta blockade, then nitroprusside
Indications for operative intervention for descending aortic disection
End-organ failure, inadequate pain relief despite medical Rx, rupture, signs of impending rupture (increasing diameter or periaortic fluid)
Unilateral hip pain on outer surface of thigh, more painful with pressure (e.g. when sleeping)
Trochanteric bursitis
What is Paget's disease of the bone and what are pts predisposed to?
Osteitis deformans: accelerated bone turnover in localized areas --> focal bony hypertrophy

Bone is weak and prone to pathologic fractures
How to distinguish trochanteric bursitis pain from that of hip OA?
Trochanteric: superficial
Hip OA: pain is deep within the joint, may be referred to inguinal area/ knee
Which manuevers worsen trochanteric bursitis vs. hip OA?
TB: external rotation or resisted abduction

OA: internal rotation
Peritoneal abdomen, bloody stool, N/V
Bowel infarction
Acute abdominal or back pain followed by syncope and eventually hypovolemic shock
AAA rupture
Where does the pain in acute renal colic start/ radiate to?
Unilateral flank pain, radiates to groin
Differentiate the swelling in a ligamentous knee injury vs. meniscal
Ligamentous: rapid from hemarthrosis

Meniscal: over 12-24hrs
"Popping" sensation in knee likely indicates
Meniscal injury
Tenderness over medial knee in athlete or obese older woman w/out popping sensation
Anserine bursitis
2 most common complications from rhinoplasty
Nasal obstruction
Epistaxis
Whistling noise after nasal surgery, and why pts are at risk for this complication
Nasal septal perforation (at risk b/c of poor blood supply: is cartilage)
Which pts are predisposed to nasal polyps
Asthma/ allergic disorders (due to chronic inflammation)
Symptom of nasal polyp and management
Chronic nasal obstruction
If symptomatic: surgical removal
Pain, tenderness, and erythema within the nose
Nasal furuncuolosis 9from staphylococcal folliculitis)
Predisposing factors for nasal furunculosis
Nose picking or nasal hair plucking
Why is nasal furuncolosis life threatening?
Can spread to cavernous sinus
What are the two most common causes of postop nasal septal perforation?
Septal hematoma
Septal abscess (much less common)
Most common iatrogenic cause of tension pnuemo
Subclavian central venous catheter placement
Malignant vs. benign breast calcifications
Malignant: microcalcs
Benign: coarse calcs
Breast biopsy with fat globules and foamy histiocytes
Fat necrosis
One week after abdominal injury w/ negative CT pt has fever, shaking chills, and deep abdominal pain
Retroperitoneal abscess from pancreatic injury (wouldn't necessarily be diagnosed on initial CT, unlike many other injuries)
Trauma pt with gross hematuria
Suspect bladder injury
Diagnostic test for suspected bladder injury
Retrograde cystogram w/ post void films
First step in management of a pt with new-onset oliguria with a Foley
Change Foley to ensure not clogged (then fluids)
Pts with Crohn's are predisposed to what GU abnormality and why?
Nephrolithiasis
Fat malabsorption --> hyperoxaluria
Struvite stones are often due to persistent infection by what bacteria?
Proteus
What are staghorn calculi?
Struvite stones that fill the entire renal pelvis
N/V, abd pain, hypoglycemia, and hypotension after stressful event (e.g. surgery)
Adrenal insufficiency
Which pts are particularly predisposed to this type of postop adrenal insufficiency?
Steroid-dependent pts
What is the cause of postop obstructive atelectasis?
Airway blockage --> retained air distal to occlusion (which is eventually reabsorbed); affected airway becomes airless and collapses
Compensation for hypoxemia due to postop atelectasis
Respiratory alkalosis (hyperventilation)
How far in advance of surgery is preop smoking cessation beneficial?
>8wks prior to surgery
If closer, actually have increased risk of postop pulm complications
Unilateral bloody nipple discharge in perimenopausal woman with no other findings on PEX/imaging
Intraductal papilloma
Why are intraductal papillomas often not palpated/ visualized on imaging?
Small size (US can only detect >1cm) and beneath areola so difficult to palpate
Rx for unresponsive trauma pt who is still hypotensive after fluids
Emergent ex lap (suspect continued bleeding)
What is Legg-Calve-Perthes isease?
Avascular necrosis of femoral capital epiphysis
Radiologic difference between SCFE and Legg-Calve-Perthes
SCFE: femoral epiphysis is structurally intact w/in acetabulum, just misaligned

LCP: severe abnormalities of epiphysis/ avascular degeneration
Hip pain w/ limp in young boy
With limp, most likely Legg-Calve-Perthes (I think?)
Child w/ limp and normal XRs
Transient synovitis of hip
Bowel sounds in ileus vs. SBO
Ileus: hypoactive/ absent
SBO: hyperactive ("tinkling")
Cause of ileus after trauma
Retroperitoneal hemorrhage associated w/ vertebral fractures
High-riding prostate, scrotal hematoma, and inability to urinate is most likely due to what kind of urethral injury?
Posterior urethra (pelvic hematoma causes the high-riding prostate)
Which type of urethral injury is commonly associated w/ pelvic fracture
Posterior urethra
2 most common causes of anterior urethra injury
Blunt trauma to perineum (straddle injury)

Instrumentation of urethra
How does intraperitoneal bladder rupture present?
Peritoneal signs on PEX
Multiple bony lesions with elevated alk phos
Paget's disease of the bone (osteitis deformans)
Paget's disease of the bone is associated with these three other conditions in the head
Increased head/hat size
CN palsies
Hearing loss
3 vaccines needed after splenectomy
S. pneumoniae, N. meninigitidis, H. influenzae
Common ortho injury after seizures and typical presentation
Posterior dislocation of shoulder
Pt holding arm adducted and internally rotated
When is surgery indicated for GERD?
10-15% of pts with GERD refractory to medical therapy
Preop requirements for GERD surgery
EGD with biopsy and esophageal manometry (to demonstrate intact esophageal peristalsis)
Surgery of choice for GERD
Nissen fundoplication (restores GEJ and LES to normal intra-abdominal position and wraps stomach around distal esophagus to augment LES tone while preserving LES relaxation)
Surveillance for Barrett esophagus
Endoscopy and biopsies ever 18-24mo to determine if it has progressed to dysplasia
Rx for Barretts with severe dysplasia
Esophageal resection (high risk of occult adenocarcinoma)
4 types of hiatal hernia
Type I: GEJ above diaphragam
Type II: paraesophageal (stomach herniates into chest but GEJ in nml location)
Type III: mixed, i.e. stomach herniates into chest + GEJ in chest
Type IV: other abd contents in chest
Why is a Type II hernia dangerous?
Risk for a gastric volvulus
Indications for surgery for H. pylori
Persistent ulcer after adequate treatment (8-12 wks of medical Rx with EGD showing persistent ulcer)
3 surgical options for H. pylori
1) Highly selective vagotomy (procedure of choice, despite recurrence risk)
2) Truncal vagotomy and pyloroplasty
3) Vagotomy and antrectomy (highest complication rate)
What should always be done in cases of persistent ulcer?
Measure serum gastrin levels
Which types of ulcer are associated with low vs. high acid?
Types I and IV: low acid
Types II and III: high acid
Where are the 4 types of gastric ulcers located?
Type I: lesser curvature
Type II: simultaneous duodenal ulcer
Type III: prepyloric
Type IV: gastric cardia/GEJ
All gastric ulcers require this diagnostic test
Biopsy to rule out malignancy
Surgical options for gastric ulcers, based on type
Antrectomy
Add truncal vagotomy if type II or III (acid producing)
How to stage gastric cancer
Abdominal explroation
Early gastric cancer surgical treatment
Distal subtotal gastrectomy
Which subtype of gastric carcinoma has teh best prognosis?
Intestinal
Resection of infiltrating gastric carcinoma includes?
Stomach, omentum, and perigastric LNs
What is linitis plastica?
Diffusely infiltratnig gastric carcinoma; involves all layers of stomach wall with marked desmoplastic reaction
Rx for linitis plastica
Total gastrectomy with splenectomy, though cure is rare
How does linitis plastica appear on biopsy?
Wall of stomach appears fixed and rigid
Cancer at the GEJ/proximal stomach has a better/worse prognosis than those in the antrum?
Worse
Surgical Rx for perforated ulcer
Close ulceration with Graham patch

If pt had previous ulcer symptoms/ treatment, should also do vagotomy and pyloroplasty
Management of perfed ulcer that appears >12hrs ago
Quick closure and then monitor in ICU for sepsis with fluids, IV Abx, and omeprazole
Two drugs with gastric mucosal protective properties
Misoprostol (PGE1 analog)
Sucralfate (topical cytoprotective)
What does an ulcer with a white base indicate?
How not bled recently, can observe
Management of ulcer visualized on endoscopy with clot and/or visible artery?
Endoscopic hemostasis
With visible artery and recent bleed, may need surgical intervention
How does the endoscopic management of gastric vs. duodenal ulcers differ?
All gastric ulcers require biopsy!
3 management options for gastric varices
More recalcitrant than esophageal:
- Cyanoccrylate glue
- TIPS
- Splenectomy
Gastritis and gastric varices in pt w/ history of chronic pancreatitis: diagnosis and management
May be due to splenic vein thrombosis --> left sided portal HTN

Splenectomy if bleeding is persistent
Rx for esophageal varices
- FFP and Vita K
- Vasopressin or octreotide to lower portal pressure
- Sclerotherapy/band ligation
Multiple linear erosions in the gastric mucosa at the GEJ
Mallory Weiss Syndrome
Rx for persistent bleeding from Mallory Weiss Syndrome
Injection or electrocautery
Three heart infections associated with Reiter's syndrome (reactive arthritis)
Myocarditis, aortitis, pericarditis
4 conditions associated with HLA-B27
Reactive arthritis
Aortic regurg
Pericarditis
Ankylosing spondylitis
Coughing up hair may indicate
Teratoma in connection with tracheobronchial tree
Which receptors do the following drugs act on, causing what effects?
Epi
B1 and B2
Which receptors do the following drugs act on, causing what effects?
Norepi
B1 and B2, at nerve synapses
Which receptors do the following drugs act on, causing what effects?
Isoproterenol
Beta agonist --> vasodilator and chronotropic
Which receptors do the following drugs act on, causing what effects?
Dopamine
Alpha-1 and dopamine receptors --> vasodilation
Which receptors do the following drugs act on, causing what effects?
Dobutamine
Similar to dopamine as strong inotrope but minimal chronotropic action
Which receptors do the following drugs act on, causing what effects?
Milirinone/amrinone
Vasodilation and inotropy via inhibition of phosphodiesterase
Which receptors do the following drugs act on, causing what effects?
Digitalis
Inhibiits NaKATPase --> positive inotrope
Which receptors do the following drugs act on, causing what effects?
Nitroprusside vs. nitroglycerin
Both are vasodilators

Nitroprusside: balanced arterial and venous dilation

Nitroglycerian: more venous effects --> venous pooling
Octreotide vs. vasopressin for bleeding esophageal varices
Octreotide is better b/c vasopressin has side effect of coronary vasoconstriction
Management for persistent esophageal variceal bleeding despite medical therapy (3)
Portosystemic shunt (high mortality)Balloon tamponade
TIPS procedure
Long-term prevention of bleeding of esophageal varices
Beta blockers
Pt with fever, chills, night sweels, weight loss, and epigastric upset
Gastric lymphoma (constitutional symptoms + epigastric upset)
Rx for pts with mucosa-associated lymphoid tissue lymphoma in the stomach
H pylori eradication only; surgery if fail to respond (more advanced gastric lymphomas reuire surgery)
8 complications from central venous catheter placement
Arterial puncture
Pneumothorax
Hemothorax
Thrombosis
Air embolism
Sepsis
Vascular perf
Myocardial perf --> tamponade
Where should a central venous catheter be on CXR?
Ideally in the SBC, but at least proximal to cardiac silhouette
First step in hip fractures from a fall in the elderly, once stabilized with pain control and DVT prophy
Determine the cause of the fall/ operative risk
Signs and symptoms of transtentorial herniation of the uncus
Ipsilateral hemiparesis
Ipsilateral mydriasis and strabismus
Contralateral hemianopsia
Altered mental status
Pain in forefoot/ btwn 3rd and 4th toes and a clicking sensation when palpating while squeezing the metatarsal joints
Morton's neuroma (positive Mulder sign)
Rx for Morton neuroma
Metatarsal support w/ bar or padded shoe inserts (on both sides so even!) to decrease pressure on metatarsal head; surgery if fails conservative Rx
What is Boerhaave syndrome?
Esophageal perforation due to recurrent retching alone
Best test for diagnosing an esophageal perf
Water-soluble esophagram
Rx for esophageal perf
Primary closure and drainage of mediastinum w/in 6hrs to prevent mediastinitis
Rx for Legg-Calve-Perthes disease (idiopathic osteonecrosis of the femoral head)
Maintaining placement of femoral head w/in acetabulum so heals in proper shape/position (w/ splints or surgery)
Tachypnea, tachycardia, hypoxia, unilateral decreased breath sounds w/in 24hrs (or even minutes) of rib fracture
Pulmonary contusion
How to distinguish pulmonary contusion from ARDS?
ARDS takes 24-48 hrs to develop and is bilateral
Appendicitis like presentation, but 5 days duration and stable pt: diagnosis and management
Likely contained abscess

IVF, Abx, bowel rest, perc drainage if possible, appendectomy in 6-8wks
Flexion of right hip against resistance elicits severe pain
Psoas sign: indicative of psoas abscess associated w/ appendicitis
Rx for apnea in pt with cervical spine injury
Orotracheal intubation w/ rapid sequence intubation (requires 4 people)
Why is needle cricothyroidotomy not useful in adults?
Risk of carbon dioxide retention
Congenital adhesions in children
Ladd's bands
Fever, urticaria, arthritis, nephritis
Serum sickness (immune complex reaction against heterologous proteins)
Burn pt with hyperglycemia, leukocytosis, tachypnea, and tachy
Sepsis (bronchopneumonia or bound wound infection)
Which wound pts need tetanus vaccine?
Dirty wound w/ last dose >5yrs ago
Clean wound w/ last dose >10yrs ago
Most common form of thyroid cancer following radiation
Papillary carcinoma
Management of pt with neck nodule with history of neck radiation
Proceed directly to thyroidectomy
Medullary thyroid cancer is associated with a mutation in which gene
RET
5 H&P findings that indicate that a neck nodule may be malignant
Hoarseness
Dyspnea
Dysphagia
Cervical LN enlargement
Vocal cord paralysis
Work-up of neck nodule
FNA
When should neck cysts be removed?
Large (>4cm) or recurs (to eliminate risk of malignancy)
Rx for a colloid nodule in the neck
Benign: medical thyroid suppression and f/u
Psammoma bodies indicate this type of thyroid cancer
Papillary
Amyloid deposits and calcitonin staining indicate this type of thyroid cancer
Medullary
Undifferentiated cells indicate this type of thyroid cancer, with this management
Anaplastic
Chemo and radiation
Hurthle cells indicate this type of thyroid cancer, with this management
Adenoma or low-grade
Lobectomy
Follicular cells indicate what diagnosis/management?
Nondiagnostic, but doesn't exclude cancer, so thyroid lobectomy indicated
Lymphocytic infiltrate indicates what diagnosis/ management
Lymphoma (Rx: radiation) or chronic lymphocytic thryoiditis (Rx: thyroid hormone replacement)
2 most common complications of thyroid surgery
Injury to recurrent laryngeal or external branch of superior laryngeal

Injury to parathyroid --> hypocalcemia
Management of papillary cancer (2 subgroups of pts)
Previous H&N radiation: total thyroidectomy

No radiation Hx: limited thyroid lobectomy and isthmusectomy (or total thyroid if >1.5cm)
Management of follicular thyroid cancer
Microinvasive: formal lobectomy and isthmusectomy

>4cm or clear cancer: total thyroidectomy
What areas have a higher incidence of follicular thyroid cancer?
Iodine deficient areas
Primary means of spread of follicular cancer
Vascular
Management of medullary thyroid cancer
Total thyroidectomy
Histologic feature of medullary thyroid cancers
Hyperplasia of C cells (parafollicular) with amyloid
Which thyroid cancers utilize postop iodine-131 ablation
Follicular (always) and papillary (sometimes, + thyroid suppression w/ thyroid hormone)
Why does medullary cancer not require I-131/thyroid suppression postop?
Tumor arises from C cells
Postop monitoring of medullary cancer uses these two serum levels
Calcitonin
CEA
Rx for parathyroid adenoma
Resection of involved gland; identification of other glands and biopsy of one to ensure normalcy
Rx for parathyroid carcinoma
Resection of all four glands
What is a sestamibi scan used for?
Preop demonstration of enlarged parathyroid glands to identify adenoma w/o need for idenftification of remaining glands (minimally invasive)
Most common site for "missing" parathyroid gland on exploration
Thymus
Common postop risk in parathyroidectomy pts
Tetany (from hypocalcemia)
What is Chvostek's sign?
Tap on facial nerve adjacent to ear --> spasm of orbicularis oris
When should asymptomatic hypercalcemia be explored
>11
Initial treatment for acute hypercalcemia (5 agents, in order)
1) Rehydration w/ normal saline
2) Furosemide
3) Mithramycin, calcitonin, glucocorticoids
Why do pts with chronic frenal failure develop secondary hyperparathyroidism
Retain phosphate from decreased GFR; hyperphosphatemia --> hypocalcemia --> elevated PTH
Indications for surgical management of secondary hyperphosphatemia
Bone pain, intractable pruritus, ectopic calcifications in the soft tissues
What is calcium tachyphylaxis?
Ectopic calcifications in the soft tissues
Surgical management of secondary hyperphosphatemia
Removal of all but 50mg of parathyroid (possible transplant it to forearm)
Pt with hyperparathyroidism who suddenly develops uncontrollable HTN
Undiagnosed pheochromocytoma
Rx for uncontrolled HTN from pheo
Combo alpha and beta blockage
What is the 10% rule with pheos?
10% malignant
10% extraadrenal
10% produce epi
10% bilateral
2 important principles in pheo resection
Minimize release of catecholamines with:
- Minimal manipulation of tumor
- Ligation of all venous drainage before tumor manipulation
Swollen tender thyroid gland
De Quervain's thyroiditis
Classically elevated lab test in thyroiditis
ESR
Histology of de Quervain's thyroiditis
Giant cell granulomas around degenerating thyroid follicles
Rx for de Quervain's thyroidits
Analgesics and aspirin; steroids in resistant cases
Rx for Hashimoto's thyroidits
Thyroid replacement and biopsy of all suspicious lesions (due to higher incidence of malignancy)
Zollinger-Ellison syndrome is associated with what familial syndrome?
MEN-1 (pancreatic endocrine tumor)
Typical localization of gastrinoma
Duodenum and head of pancreas (gastrinoma triangle)
Primary chemo agent used for tumor control of gastrinoma
Streptozocin
What is the Whipple triad and what tumor does it indicate?
Fasting hypoglycemia, symptomatic hypoglycemia, relief w/ glucose admin

Insulinoma
Rx for unresectable insulinoma
Diazoxide (inhibitor of insulin release)
Rx for incidentally identified adrenal mass
>5cm: surgical excision (high likelihood of adrenal cortical carcinoma)
<5cm: observation (if normal catecholamines, cortisol, and K+)
Most likely diagnosis with CXR appearance of:
popcorn
Hamartoma
Most likely diagnosis with CXR appearance of:
bulls eye configuration
Benign
Most likely diagnosis with CXR appearance of:
calcium-containing
Granuloma (not malignant)
Diagnostic tests for CXR mass
CT and then needle biopsy
Main risk of needle biopsy
Pneumothorax
What doubling time favors malignant nodule?
5wks to 280 days
What does a low CT density number (<100) indicate
Favors malignant status
3 common cancers that metastasize to the lugn
Colorectal
Breast
Renal
Lung nodule associated w/ a dental abscess and with chest wall involvement
Actinomycosis
Lung nodule associated w/ chronic skin ulcers
Blastomycosis
Preop eval for pneumonectomy
Cardiac: EKG and echo (for EF and wall motion)
Lungs: PFTs, V/Q scan
2 causes of a widened mediastinum
Aortic aneurysm
Hilar LAD
What is the hilum and what does it contain
Pedicle that attaches lung to medistinal structuers

Pulm artery, pulm vein, main bronchus (bilaterally)
What stage is lung fcancer with positive ipsilateral hilar LNs?
Stage II
What stage is lung fcancer with positive mediastinal LNs?
Stage III
Where is a Pancoast tumor located and what vessel produces that space?
Apex of the lung in the groove (superior sulcus) produced by the subclavian artery
Workup of lung nodule identified on CXR (4 pts)
CT
Possibly bronchoscopy and mediastinoscopy
Needle biopsy
Rx for Pancoast tumor
Irradiation for 6wks
Then surgical resection of involved chest wall and lung
Hemoptysis in healthy young non-smoker
Most likely from bronchial adenoma (also consider TB)
Why do bronchial adenomas cause hemoptysis?
Vascular and arise within bronchi, often obstructing them (--> atelectasis)
2 types of bronchial adenomas
Carcinoid tumors
Adenocystic carcinomas
Rx for bronchial adenoma
Lovectomy
Pleural effusion in 70yo
Cancer until proven otherwise, though most likely heart failure
Diagnostic test for pleural effusion not related to CHF
Thoracentesis and pleural biopsy
What is pleural fluid cultured for (in addition to looking for malignant cells)?
Bacteria, TB
Rx and likely prognosis for mesothelioma
Extrapleural pneumonectomy is the only potential cure; high mortality E
Etiology of spontaneous pneumo
Rupture of apical blebs
Two causes of rupture of apical blebs
Spontaneous
Strenuous activity
What two signs indicate that a spontaneous pneumo is a tension pneumo?
Total lung collapse
Mediastinal shift
How does a water seal for a chest tube function?
Maintains a negative pressure in pleural space and chest tube so that air and fluids may escape from the chest, and creates a one-way valve to prevent air and fluids from reentering the cavity
Rx for recurrent pneumothorax
Thoracoscopic excision of blebs and pleural abrasion (pleurodesis), which causes irritation --> adhesions
Which wound pts need tetanus IG?
<3 doses of tetanus vaccine or dirty wound with unknown immunization status
Management of pt with hypotension and possible aortic aneurysm
Explore in OR (+/- ultrasound for diagnosis, but no time for CT)
Unstable trauma pt with CXR showing widened mediastinum, large left hemothorax
Aortic injury
Causes of a psoas abscess
Not just appendicitis; also contiguous spread from nearby bone or bowel, or hematogenous spread from furuncles or other infection
Which part of the bone is associated osteosarcoma vs. Ewing's sarcoma?
Osteosarcoma: metaphyses (rapid bone growth)

Ewing's: diaphyses
Osteolytic lesion with onion skin appearance
Ewing's sarcoma
"Sunburst" pattern or periosteal new bone formation w/ elevation (Codman's triangle)
Osteosarcoma
In which malignant bone tumor is alk phos elevated?
Osteosarcoma
Which malignant bone tumor has bone pain worse at night, often precipitated by trauma?
Osteosarcoma
Which malignant bone tumor is associated with systemic symptoms (fever, malaise, weight loss)?
Ewing's sarcoma
Soap bubble appearance of bone (due to osteolysis)
Osteoclastoma (giant cell tumor of bone)
DRE with tender, fluctuant mass palpable only w/ tip of finger
Pelvic abscess (in rectovesical pouch)
Presentation of pelvic abscess
Fever, leukocytosis, painful defecation, diarrhea (from bowel irritation)
Most common cause of pelvic abscess in men vs. women
Men: appendicitis
Women: gyne infection
Rx for pelvic abscess
Drainage
Flaccid paralysis after vascular surgery
Spinal cord ischemia
Which part of the spinal cord is most vulnerable to infarction
Thoracic
Diagnostic test and Rx for postop spinal cord ischemia
MRI

Lumbar drains to reduce spinal pressure
Fat embolism is often secondary to?
Long bone fracture
Few days after trauma w/ dyspnea, tachypnea, chest pain, hypoxemia worsened by fluids, and patchy alveolar infiltrates on CXR
Pulmonary contusion
Hx of PNA now with pleural effusion
Empyema
Why are empyemas often culture negative?
Previous treatment
When to suspect G- with empyema
Alcoholic, unconscious, recent op, pulmonary aspiration
Management of empyema (3)
Abx
Evacuate pus
Reexpand lung
(chest tube for last 2)
Rx for loculated empyema
Thoracotomy and decortication
Three vessel disease indicates blockages in what three arteries?
Right main
LAD
Circumflex
Most common conduits used to bypass obstructed coronaries (2)
Greater saphenous vein grafts
Internal thoracic (mammary) artery (best patency)
2 important components of cardiopulmonary bypass
Cardioplegia solution (enough potassium to stop heart)

Hypothermia
Average mortality for CABG surgery
3%
Repair options for mitral valve stenosis
Commissurotomy (splitting commissures and reconstituting lumen w/ dilation)
Repair options for mitral regurg
Excising insufficent/redundant portions of leaflets and narrowing/reinforcing mitral annulus w/ annuloplasty ring
Option for mitral valve disease if repair isn't feasible
Prosthetic valve
Work-up of newly diagnosed aortic stenosis
Cardiac cath to determine status of coronary circulation (better outcomes of valve replacement if intact)

Carotid Doppler to r/o internal carotid obstruction
Difference btwn mechnical (metal/plastic) and tissue valves
Mechanical require anticoagulation

Tissue deteriorate, require replacement at ~7yrs
What causes a Zenker (pulsion/pharygneal) diverticulum
Abnormal uncoordinated constriction of cricopharygneal muscle during swallowing, which increases the pressure in this area of pharynx and forces out a pouch of mucosa covered by pharygneal muscle
What is another type of esophageal diverticulum and where is it?
Epiphrenic (near distal GEJ)
Etiology of achalasia
Loss of smooth muscle ganglionic cells of Auerbach's plexus and neuronal degeneration
Rx for achalasia (2)
Disruption of lower-esophageal high-pressure zone w/ dilation:
- Heller myotomy
- Endoscopically w/ transesophageal pneumatic dilation (only 60% successful, vs 100% for Heller)
Fever, dysphagia, odynophagia, drooling, and submandibular swelling w/ crepitus
Ludwig angina (rapidly progressive bilateral cellulitis of submandibular and sublingual spaces)
Cause of Ludwig angina and involved bugs
Infected mandibular molar

Strep and anerobes (--> crepitus)
Management of Ludwig angina (3)
Abx, removal of infected tooth
Monitor for respiratory difficulty and intubate if necessary (asphyxiation is most common cause of death)
Why is traumatic rupture of the diaphragm more common on the left?
Liver is protective on the right
Diagnostic tests for ruptured diaphragm
CXR raises suspicion
Barium swallow or CT w/ oral contrast are diagnostic
Needle shaped crystals on UA
Uric acid stones
Why do uric acid stones need to be evaluated by CT or IV pyelography?
Radiolucent
Three components of GCS and their max points
MVE: Motor Response (6), Verbal Response (5), Eye Opening (4)
Rx for clot in the superficial femoral vein
Still heparin! Is actually a deep vein, is just the distal part of the femoral vein
Management of trauma pt with splenic injury on US (2 diff scenarios)
Unstable: emergent XL
Stable: CT to determine splenic injury and need for operative repair
What is the final sequel of compartment syndrome
Volkmann's ischemic contracture (dead muscle has been replaced with fibrous tissue)
4 possible complications of diverticulitis
Abscess
Perforation
Obstruction
Fistula formation
Rx for fluid collection/abscess formation after diverticulitis (dependent on size)
<3cm: IV Abx and observation
>3cm or worsening symptoms: CT-guided drainage; if unsuccessful, surgery for drainage and debridement
Rx for diverticulitis w/ fistula, perforation, or obstruction
Sigmoid resection
Tenderness over a bony surface that is worse with palpation
Stress fracture
Burning, numbness, and aching of the distal plantar surface of the foot/ toes
Tarsal tunnel syndrome
Pain and tenderness particularly w/ flexion/extension of hand/wrist after a bite or puncture wounds
Tenosynovitis
Most common tumor of posterior mediastinum
Neurogenic tumors
Diagnostic test for neurogenic tumor, and what are you looking for?
CT scan
Determine whether tumor is present in spinal canal
Management for neurogenic tumor in posterior mediastinum/spinal canal
Combined thoracic and neurosurg approach
2 most common tumors of the middle mediastinum
Lymphatic tumors
Various cysts
Two most common type of middle mediastinal cysts
Bronchogenic
Pericardial (water bottle appearance)
Management of mediastinal cysts
Removal due to potential inflammatory complications, i.e. fistula formation
Most likely histopath of esophageal cancer by location
Upper and middle third: squamous cell
Lower third: adeno
Staging workup for esophageal cancer
EUS (for wall penetration and LNs), CT C/A for celiac LNs
Rx for cancer of the cervical and upper third of the esophagus
Irradiation (chemoradiation)
Rx for cancer in the middle third of esophagus
Neoadj rads/chemo hopefully to allow surgical resection
2 esophagectomy options
Transhiatal esophagectomy
Formal esophagectomy utilizing a neck anastamosis (gastroesophageal)
Advt of a neck anastamosis
Can manage anastamosis leak easily, which is a common postop complication (10%)
Rx for cancer in the distal third of the esophagus
Esophagectomy and proximal gastrectomy
How can an esophageal carcinoma cause constant cough?
Chronic aspiration from tracheoesophageal fistula due to tumor erosion into the trachea
Rx for advanced esophageal cancer
Palliation with gastrostomy, esophageal stents, radiation, or palliative resection
Recurrence rate of TIA without treatment
40%
Periop stroke risk during carotid endarterectomy
1-3%
3 nerves at risk during carotid endarterectomy
Hypoglossal, vagus, marginal branch of facial
Med to send pts home on after carotid endarterectomy
ASA
Cause of amaurosis fugax
Emboli from carotid bifurcation --> internal carotid --> ophthalmic artery (first branch of ICA)
What is a Hollenhorst plaque
Portion of embolus seen on retinal exam as bright shiny spot in retinal artery
One extremity w/ absence of distal extremity pulses, cool and cyanotic, decreased sensation, weakness
Acute arterial embolus
Rx for acute arterial embolus
Heparin and immediate OR (better recovery with quicker revascularization)
Procedure used to treat acute arterial embolus
Balloon catheter embolectomy
Procedure done during embolectomy to ensure adequacy of procedure
Intraop arteriogram
Inability to dorsiflex foot + calf tenderness after embolectomy
Compartment syndrome
Cause of postop compartment syndrome
Ischemia-reperfusion injury (edema after reperfusion)
Long-term therapy after embolectomy
Chronic anticoagulation with warfarin
Hairless leg, loss of sensation, thin/shiny skin
Suggestive of chronic ischemia from peripheral vascular disease
Where is claudication pain most commonly located?
Calf
ABIs for normal, mild claudication, severe (multilevel occlusion), and rest pain/tissue loss
Normal: >0.9
Mild: 0.6-0.8
Severe: <0.5
Rest pain: <0.3
How does the Doppler wave form change with occlusive disease
Normal triphasic --> biphasic with moderate stenosis (less compliance) --> monophasic with severe stenosis
Unilateral absence of femoral pulse
Aortoiliac occlusive disease
Management of aortoiliac occlusive disease
Often surgery, as is generally more progressive than more peripheral occlusive disease
Surgical treatment for aortoiliac occlusive disease
Balloon dilation and/or stent placement or surgical revascularization
What is important to evaluate in a diabetic with peripheral vascular disease and a foot ulcer?
Whether bloody supply is sufficient to allow ulcer to heal; if not, will require revascularization
Arteriogram may demonstrate two patterns of occlusive disease
Inflow disease: inadequate blood blow into femoral artery (E.g. aortoiliac disease)

Outflow disease: single or multiple occlusions of leg arteries, esp superficial femoral or popliteal
F/u and long-term management after vascular bypass surgery
Frequent duplex exams of graft
ASA, lipid control, foot care
Impotence, calf/thigh pain on exertion and relieved by rest, smoker, absence LE pulses
Aortoiliac disease 2/2 atherosclerosis
What is Leriche syndrome?
Aortoiliac disease 2/2 atherosclerosis
When should arteriograms be performed for aortoiliac disease/ low extremity disease?
Not until a decision to proceed with surgery has been made
3 treatment options for aortoiliac disease
Lifestyle modification, percutaneous transluminal angioplasty, aortobifemoral bypass
Percutaneous transluminal angioplasty vs. aortobifemoral bypass
PTA best for signle, short-segment iliac stenosis

Bypass best for bilateral loss of pulses/ occlusion of entire system
Alternative to aortobifemoral bypass for high risk pt
Axillofemoral bypass graft
Painful, cyanotic big toe after revascularization
"Trash foot": atheroembolization of fibrin, platelets, or disloged atherosclerotic debris that has blocked small pedal or digital arteries during unclamping
Rx for trash foot
Heparinization followed by long-term antiplatelet therapy
Likelihood of a cardiac event during vascular surgery
Up to 10% for MI, arrhythmia, or heart failure in major vascular reconstruction
Method used to assess cardiac risk in pts w/ various backgrounds (3 categories)
Class III/IV CHF or EF <20%: coronary angiography

Asymptomatic: straight to surgery

History of MI/moderate angina: DT scan
How long should a vascular procedure be delayed after MI
At least 3mo
Eagle's criteria in prediction of periop cardiac morbidity (6)
>70yo
DM
Angina
Ventricular arrhythmia
Q waves on preop EKG
DT scan redistribution
How fast, on average, do AAAs grow?
4mm/yr
Cause of erectile dysfunction after AAA repair
Interupption of hypogastric circulation or autonomic nerves on aorta
Rx for hypotensive pt with ruptured AAA
Straight to OR; no IVF first b/c could convert contained rupture into free intraperitoneal rupture
HDS patient with AAA and history of syncope/abdominal pain
CT scan; if AAA present, esp w/ nearby hematoma, to OR
Pt with postop ischemic colitis, sigmoidoscopy demonstrates limited to mucosa
Bowel rest, GI decompression, ABx, frequent rescoping
Pt with postop ischemic colitis, sigmoidoscopy demonstrates full thickness involvement
Resection of nonviable bowel and end colostomy
2mo after AAA repair pt is febrile with inflamed femoral incision
Vascular graft infection, usualyl from skin flora
Diagnostic test for suspected vascular graft infection
CT
Rx for vascular graft infection
Complete removal of graft, debridement of all infected tissues, revascularization by extra-anatomic bypass, long-term Abx
Pt with history of aortic surgery/vascular graft and new onset upper GI bleeding
Eval for aortoenteric fistula
Diagnostic test for aortoenteric fistula
CT abd or angiography
Rx for aortoenteric fistula
Removal of graft, repair of GI tract, extra-anatomic bypass
Abd pain, weight loss, intermittent diarrhea, multiple abdominal bruits
Chronic mesenteric ischemia
Diagnostic test for chronic mesenteric ischemia
Mesenteric arteriogram
Rx for chronic mesenteric ischemia
Revascularization using bypass graft from aorta
Tearing chest/back pain, diaphoresis, HTN
Aortic dissection
Rx for aortic dissection
Beta blockers unless invovl;es ascending aorta (requires surgery)
Why can warfarin be hypercoagulable early on?
Protein C deficiency
DVT pt with chronic, marked edema; skin ulceration around ankles; venous claudication
Postthrombotic syndrome due to chronic venous HTN in lower leg
Rx for postthrombotic syndrome
Chronic use of support hose (good prevention as well)
When do pts with a mild to moderate TBI need neuroimaging? (4 symptoms)
Brief LOC
Vomiting
Headache
Disorientation
Difference btwn tibial stress fracture and medial tibial stress syndrome on exam
Latter (shin splints) have no tibial tenderness on palpation
What is the respiratory quotient (RQ)?
Ratio of CO2 produced to O2 consumed; assessment of metabolism
Causes of RQ of 0.8, 1.0, 1.05
0.8: high protein diet or sepsis
1.0: Largely carbohydrate diet
1.05: Mechanically ventilated pt
Why is RQ imp in intubated pts?
High RQ can indicated overfeeding w/ carbs that --> excessive CO2 production which will make weaning more challenging, esp in pts with preexisting lung disease
Abd pain, bloody diarrhea, fever, and leukocytosis after AAA repair
Bowel ischemia
Acute rectal bleeding with blood that fills the toilet
Diverticulosis is most likely
Time line of development of postop infections
PNA (<2 days), UTI, DVT, wound infection, drug fever (>7 days)
2 most common causes of drug fever
Anticonvulsants
Bactrim
How to differentiate pneumothorax from cardiac tamponade in pt with hypotension and JVD
Decreased breath sounds and mediastinal deviation in pneumothorax
Where to perform needle thoracostomy
2nd intercostal space in midclavicular line
Pneumomediastinum, subQ emphysema, and persistent pneumo despite chest tube placement
Bronchial rupture
Pt who cannot lower arm smoothly (drops rapidly from 90 degree position)
Rotator cuff tear
Hypotension and back pain after cardiac cath
Retroperitoneal bleeding
Chronic immobile hard mass on hard palate
Torus palatinus: congenital benign exostosis (bony growth)
When does torus palatinus need surgical correction?
Symptoms, interferes w/ speech or eating, or problems with fitting dentures
Pt with claudication signs but normal ABI
Exercise testing with repeat ABI
ABI <0.9 indicates how severe of an occlusion?
>50% in a major vessel
Which pts need a Td booster even if their last shot was within 10 yrs?
Dirty wound if shot >5yrs ago
Which patients need Td booster?
Last dose >10yrs ago
OR
Severe or dirty wounds and last dose >5yrs ago
Which pts need tetanus immunoglobin?
Unimmunized (or unknown)
OR
Last Td >10yrs ago and dirty wound
4 strategies for control of tetanus symptoms
Abx (metronidazole and penicillin)
Removal of unbound tetanospasmin (with TIG)
Control muscle spasms
Airway protection
Causes of esophageal ulceration (6)
Instrumentation
High pressures from persistent vomiting
Pill esophagitis
Barrett's --> ulcer
Infectious esophageal ulcer (Candida)
Ingestion of caustic substance
Diagnostic test and surgical option for suspected meniscal tear
MRI
Arthroscopy (or open surgery)
Why are fractures of the 2nd, 3rd, and 4th metatarsals managed conservatively?
Surrounding metatarsals act as splints and nonunion is uncommon
Hypotension and tachycardia, but with a high PCWP that increases further with fluids
Cardiac shock, e.g. myocardial contusion
Abd pain radiating to groin, N/V, and soft abdomen
Renal colic from obstructed kidney stone
6 signs of necrotizing surgical infection
1) Intense pain in wound
2) Sepsis
3) Decreased sensitivity at wound edges
4) Cloudy gray discharge
5) Tense edema outside skin
6) SubQ gas w/ crepitus
Which type of pts often get necrotizing infections postop?
Diabetics
Rx for postop necrotizing wound infection
Surgical exploration and debridement
Possible cause of cardiac arrest immediately after intubation in trauma pt
If pt is hypovolemic, the increase in intrathoracic pressure decreases venous return + venous dilation from sedatives --> cardiac arrest
How to prevent postop bacterial parotitis
Adequate hydration and oral hygiene
What is an abdominal succussion splash, and what does it indicate?
Auscultate upper abdomen and rock pt back and forth at hips; retained gastric material >3hrs --> splash sound

Indicates gastric outlet obstruction
Causes of gastric outlet obstruction
Malignancy, PUD, Crohn's, strictures (2/2 ingestion of caustic agents), gastric bezoars
Pathophys of biliary colic
Ingestion of fatty meal --> gallbladder contraction --> gallstone pushed against cystic duct (stone falls back when GB relaxes)
Cause of abdominal pain referred to the shoulder
Peritonitis --> irritation of diaphragm
Region of the bladder most susceptible to injury, and region that is covered by peritoneum (thru which urine can leak into peritoneum)
Bladder dome
Most common site of extraperitoneal bladder rupture
Bladder neck
Management of suspected SBO with acidosis
Laparotomy
Management of duodenal obstruction 2/2 hematoma
NGT with parenteral nutrition until hematoma resolves (1-2wks)
Burning pain and paralysis in upper extremities only
Central cord syndrome
Which pts often develop central cord syndrome and from what injury?
Elderly pts 2/2 forced hyperextension of neck
Ipsilateral motor and proprioception loss and contralateral pain loss below level of lesion
Brown Sequard syndrome (hemisection of cord)
Loss of motor function below lesion level w/ loss of pain and temp on both sides below lesion (but maintain proprioception)
Anterior cord syndrome
Common cause of anterior cord syndrome and best diagnostic test for extent of neurologic damage
Burst fracture of vertebra

MRI
Paraplegia, variable sensory loss, urinary and fecal incontinence
Cauda equine syndrome
Dose for prophylactic low dose heparin?
5000U SQH preop and q8-12postop
Most common ABG abnormality in PE
Decreased PCO2 due to hyperventilation
Management of a PE while on heparin therapy
Failure of anticoagulation --> IVC filter
Pt being anticoagulated w/ heparin for DVT who vomits 100ml of blood but is HDS
D/c systemic anticoagulation immediaetly; provide IVC filter
Woman with cervical cancer extending into pelvic wall w/ acute edematous, cyanotic, painful left leg
Phlegmasia cerulea dolens (inflammatory, cyanotic, painful): acute interruption of venous outflow from obstruction 2/2 pelvic malignancy (extreme ileocaval DVT)
Possible complication of phlegmasia cerulea dolens
Sensory and motor loss and possibly venous gangrene
Rx for phlegmasia cerulea dolens
Anticoagulation and leg elevation; monitor viability of tissue, rarely may require venous thrombectomy
Management of lack of gag reflex in trauma pt
Inspect airway digitally for foreign bodies
Blunt trauma to neck + hoarseness, change in voice, or stridor (most likely diagnosis + management)
Suspect laryngeal edema; need intubation befoer airway obstruction occurs
What GCS score is an indication for intubation?
8 (or less)
Common cause of simple pneumothorax in trauma pt
Rib fracture that lacerates visceral pleura and underlying lung parenchyma
When can a chest tube be removed?
Lung is fully inflated (on repeat CXR) and no further air leak is apparent
After insertion of chest tube, large amt of air leaks over next 6hrs and lung remains only partially inflated
Major airway injury (disruption of bronchus or trachea): requires thoracotomy and lung resection to repair injury
When can a pneumothorax be observed?
Small, not enlarging, no free fluid in pleural space, no other injuries, AND asymptomatic pt
Typical cause of tension pneumo
Lung lac that acts like one way valve (allows air to enter pelural space but prevents it from escaping --> increased positive pressure)
When do pneumothorax pts need needle thoracostomy before chest tube placement?
Tension pneumo (hypotensive)
Management of cardiac tamponade (initial and subsequent)
Subxiphoid pericardiodentesis (or pericardial US) or needle aspiration

To OR for pericardial window and to stop bleeding source
How much blood loss is necessary before see tachycardia; how much before hypotension?
15% (750-1500ml)

30% (1500-2000ml)
After how much blood loss do pts usually require transfusion?
30% (1500-2000ml)
Should you insert a central catheter on the same side or opposite side as a pneumothorax?
Same side; otherwise could develop one on opposite side as complication of insertion
Why doesn't a head injury usually cause hypotension?
Cushing reflex: maintains BP + pt becomes bradycardic
Concern with intubation of pt with possible cervical spine injury
Cannot tilt the head; need in-line traction to maintain cord alignment, or nasotracheal intubation
Trauma pt with priapism
Suspect spinal cord injury
5 signs of spinal cord injury in trauma pt (other than loss of motor function in extremities)
Priapism
Loss of anal sphincter tone
Loss of vasomotor tone
Bradycardia
Intestinal ileus
2 indications for thoracotomy based on chest tube output
>1500ml initially
>200ml/hr for 3 hrs
Concern with stab wound below clavicle + hypotension (and management)
Subclavian arterial or venous injury

Perform angiogram if pt stable; surgical exploration if not
Difference in management of gunshot wound vs. stab wound
Unpredictable bullet path, so often need abdominal exploration if wound near abdomen
Why is a portable CXR unrelaible for diagnosing thoracic aortic transection
Tends to magnify mediastinum
Diagnostic test for suspected aortic injury
Aortic angiography (or CT of chest)
When is a diagnostic peritoneal lavage most useful?
Unclear diagnosis of abdominal injury and pt is hemodynamically unstable (is an alternative to FAST scan)
Indications for surgical exploration on diagnostic peritoneal lavage?
>10ml of blood on opening, >100,000 RBCs on lavage fluid
Vegetable matter
Bile
Diagnostic test for suspected pelvic bleed
Pelvic angiogram
Most likely source of pelvic bleed and management
Branch of internal iliac artery
Embolization
What is essential before removing a damaged kidney?
Document presence of two kidsneys with IV pyelogram
Management of a flank hematoma
Often 2/2 renal parenchymal injury; can be observed in stable pts
Management of blood on opening the peritoneum
Pack all 4 quadrants with gauze to stop bleeding; attempt hemostasis one at a time
Post cardiac surgery w/ fever, leukocytosis, tachy, chest pain, and sternal wound drainage
Mediastinitis
Rx for postop mediastinitis
Drainage, surgical debridement, and prolonged Abx
Unilateral LE edema that worsens while at work (e.g. when legs are dependent)
Venous valve incompetence
Damage to facial nerve causes what symptom
Facial droop
Anterior shoulder dislocation can damage which nerve?
Axillary nerve
Weakness worse in upper extremities
Central cord syndrome
Bilateral loss of vibratory and proprioceptive sensation
Posterior cord syndrome
Bilateral spastic motor paresis
Anterior cord syndrome
Anterior cord syndrome is due to occlusion of what artery?
Vertebral artery
Abx for mastitis
Dicloxacillin or cephalosporins
Tenderness in anatomic snuffbox likely indicates
Scaphoid fracture
Rx for scaphoid fracture
Wrist immobilization for 6-10wks (if nondisplaced) due to risk of nonunion
Lack of pain and temp sensation in upper extremities
Syringomyelia
Cause of syringomyelia
Disruption of CSF drainage from central cord of spinal cord --> fluid filled cavity compressing neural tissue
Pulsatile groin mass below inguinal ligament
Femoral artery aneurysm
Why do femoral artery aneurysms cause anterior thigh pain
Compression of femoral nerve, which runs lateral to the artery
Management of traumatic amputation in the field
Limb/digit wrapped in sterile gauze, moistenized with sterile saline, placed in plastic bag on ice while transported to ED
Confusion, wheezes, seizure post smoke inhalation
Suspect CO poisoning
Rx for suspected CO toxicity
100% oxygen via nonrebreather facemask (hyperbaric oxygen if unresponsive)
3 types of retroperitoneal hematoma and management of each
Zone 1- central hematoma (abdominal exploration)
Zone 2- kidney (observe unless unstable)
Zone 3- pelvic hematoma (explore only if from penetrating trauma to exclude vascular injury)
Blood behind tympanic membrane or ecchymosis in mastoid region/ around eyes
Indicates basal skull fracture
CSF leaking from ear or nose
Indicates basal skull fracture
Why does hypothermia lead to poor outcomes in trauma pts
Coagulopathy from platelet dysfunction and prolongation of PT and PTT
Pt with ongoing intraabdominal bleeding who has oliguria, abd distension, and difficulty respirating
Worry about abdominal compartment syndrome
If pt doesn't respond to fluid challenge, 2 ways to see if they are truly volume depleted
CVP
PCWP if place Swan-Ganz cathether

Both indicate hypovolemia if low
Previous stab injury now with SOB, tachy, murmur, JVD
Traumatic arteriovenous fistula --> high output cardiac failure
What is Branhma's sign?
Occlusion of fistula --> drop of 10bpm in HR
Management of flail chest
Adequate ventilation (may need intubation), administration of O2, careful fluid balance to avoid pulmonary edema
Management of hematoma after stab wound to the neck
Surgical exploration
When is a preop angiogram useful in pts with neck injuries?
Wound in Zone 1 or 3 (below or avoid cricoid) and HDS pt
Management of asymptomatic carotid injury or thrombosis
Anticoagulation
Parkland formula
Volume of LR = %BSA burned x weight x 4ml/kg

Give 1/2 that volume over first 8hrs, second half over next 16hrs
When are topical Abx needed for burns, and what is commonly used?
Deep wounds
Silver sulfadiazine
Burn pt with hematuria
If RBCs seen in urine, pt has myoglobulinuria, at risk for ATN
Management of myoglobulinuria
Fluids, alkalinization of urine, osmotic diuresis
Burn pt with chocolate brown blood, central cyanosis of trunk, or even seizures/coma
Methemoglobinemia (iron in ferric (Fe3+) form, which can't bind O2)
Management of methemoglobinemia
IV methylene blue (hyperbaric oxygen in extreme cases)
Work-up of electrical burn
Potential interior damage, so: EKG, cardiac enzymes, maintain high urine ouput, alkalinize urine
What should a patient on TPN's nitrogren balance be?
Positive (esp if amlnourished or in severely catabolic state)
Type of coma seen in TPN (3 descriptive words) and its cause
Hyperglycemia, hyperosmolar, nonketotic 2/2 dehydration following excessive diuresis due to hyperglycemia
Which organ is often damaged by TPN?
Liver (fatty liver or structural damage; even cirrhosis over years)
Asian immigrant with mass in posterior nasal cavity
Nasopharyngeal carcinoma
3 common presentations of nasopharyngeal cancer
Recurrent otitis media
Recurrent epistaxis
Nasal obstruction
Nasopharyngeal cancer is associated with these 3 risk factors
EBV infection
Smoking
Nitrosamine consumption
Best option to control bleeding in massive hemoptysis
Intubation, place bleeding lung in dependent position, fluids, and:
Bronchoscopy
Definition of massive hemoptysis
>100ml blood / 24hrs
LUQ pain, hypotension, and left shoulder pain
Splenic lac (shoulder pain is from splenic hemorrhage irritating the phrenic nerve and diaphragm: Kehr sign)
Test for meniscus tear vs. MCL/LCL tear
McMurray's for meniscus
Valgus/varus for ligaments
Injury from torsion of knee with foot planted; popping sound and severe pain at time of injury; slow swelling; locking during terminal extension
Medial meniscus tear
Management of suspected scaphoid fracture with normal imaging
Thumb spica cast and reimage in 7 days
Best diagnostic test for development dysplasia of the hip (2 groups)
<4mo: ultrasound
>4mo: xray
Treatment options for resistant dumping syndrome (2)
Octreotide or reconstructive surgery
Dropping of contralateral pelvis when pt stands on one foot
Trendelenburg sign
Cause of Trendelenburg sign
Weakness of gluteus medius and minimus (innervated by superior gluteal nerve)
How to rapidly normalize INR
FFP
Which pts get acalculous cholecystitis?
Chronically ill pts in ICU (multiorgan injury, trauma, severe burns, sepsis, TPN)
Rx for critically ill pt with acalculous cholecystitis
Percutaneous drainage and Abx
Management of very classic appy presentation
Emergent surgery (don't wait for CT)
Management of SCFE
Surgical pinning of the femoral head
Where is the fluid collection in a hydrocele?
Tunica vaginalis due to patent processus vaginalis
When is surgical repair for a hydrocele indicated
After 12mo due to risk of inguinal hernia