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55 Cards in this Set

  • Front
  • Back

The structure of DNA was conclusively determined by

X-ray crystallography

The conclusion drawn from bacteriophage experiments in which the phage was either labeled with 35S or 32P was that

DNA was the hereditary material of cells

The phosphodiester bonds that connect nucleic acids together into polmers also provide orientation to the strands. This orientation

Exhibits a 5' prime and 3' prime end

Cells in amulticellular organism that function as a grouo to perform a commen function

Tissue

The # of photons in a solution of pH 3 is _____ times greater than in a solution of pH 7

10,000

In eukaryotes, the stop codon causes a water molecule to attached to the c-terminus of

The elongating polypeptide

A mutation that results in an amino acif sequence change of a protein is termed a _______ mutation

Missense

This model of DNA replication, where each orignal strand is used as a template to build a new strand, is called the

Semiconservative method

Transcriptional control proteins increase the rate of transcription by binding to

Enhancer sequences within the DNA

Homologous chromosomes

Carry information for same traits

Ionic bonds are characterized by

Unequal sharing of electrons between atoms


A pH>7 is

Basic

The replicon includes all of the following except

RNA polymerase

The double-stand of a DNA molecule are stabilized by

Hydrogen bonds between complimentary base pairs

RNA primers are removed and replaced with DNA during lagging-strand synthesis by which enzyme

DNA polymerase I

Water molecules are polar with ends that exhibit partial positive and negativr charge. Such opposite charges make water molecules attract each other though bonds called

Hydrogen bonds

During DNA replication, the ________-_____ is characterized as continuoud because its DNA template is running in the 3' to 5' direction

Leading strand

The error ratr of DNA replication is approximately 1000 times lower because of which unique function of DNA polymerase III

A proofreading subunit

The energy for synthrsizing DNA is directly obtained from

dNRPs

Which of the following distinguishes RNA from DNA

Single stranded


Thymine replaced by uracil


Ribose


Hairpin structures


All of these

RNA polymerase

Binds to promoter


Synthesizes RNA from a DNA template


Synthesizes RNA in the 5' and 3' direction


Requires additional transcription factors for normal catalytic activity


All of these

During which phase of translation is GTP used to catalyze peptide bond formation

Initiation and elongation

Protein structure is a function of

The amino acid sequence


hydrogen bonding


hydrophobic interactions


Salt-bridges

Which of the following characteristic are necessary to being "alive"

Order


Sensitivity


Growth, developmet, and reproduction


Regulation

In prokaryotes, regulatory proteins shut off transcriptions by binding to a site immediately in front of the promoter and often even overlapping the promoter. This site is referred to as

The operator site

Histone are tightly packed with DNA into ______, which condense DNA in the nucleus

Nucleosomes

Basal transcriptions factors include _________ which bind to DNA at the TATA box and facilitate mRNA synthesis in eukaryotes

TFIID

mRNA may be modified by additi9n of which of the following

5' GTP "cap"


3' poly-A tail

Chlorine has 17 electrons arranged in three energy levels. The outer level has seven electrons. In order to become stable, tje atoms gains an electron thus filling the valence orbital with 8 electrons and subsequently becomes an ion with

1 negitive charge

In the crystal matrix of ordinary salt, the sodium and chlorine are held together by

Ionic bonds

Micro RNA induces gene silencing in drosophila by

Binding directly to mRNA forming a ds structure

Mature mRNA is stabilized in the cytoplasm by

5' GTP cap

Introns qre removed from primary mRNA transcripts by the

Spliceosomes

Conside4 the lac operon. The repressor protein will________ to/from the __________ site in the presense of lactose

Dissociate; operator

Nonpolar molescules tend to aggregate in water because they are forced to come into close proximity with each other due to

Hydrophobic interactions

Nucleic acids are polymers that uniquely contain

Rings of nitrogen bases

Most viruses form a capsid around their nucleic acid core. This capsid is composed of

Protein

Virulent viruses multiply within infected cells eventually

Cause lysis of the host cell, releasing new viruses

MRNA may be modified by the addition of which of the following

5' GTP "cap"


3' poly-A tail

Recently a class of infectious proteins with no associated nucleic acid have beeb identified. They are referred to as

Prions

The HIV virus is concidered a ______ virus because afyer getting integrated into the host cell chromosomes it does not begin replicating immediately

Temperate/lysogenic

Each HIV partical posseses a________ on its surface that precisely fits a cell surface marker protein called CD4 on the surfaces of the immune system cells called macrophages and T cells

Glycoprotein

Three fatty acids bonded together with a glycerol are found in

A trigleceride

Biological membranes contain bilayers of which of the following lipids

Phospholipids

A layer of lipoprotein and glycoproteins that covers the outer surface of some viruses is the

Envelope

Virues that cause lysis of their host are called

Virulent

What is the difference between a robonucleotide and a deoxyribonucleotide

Ribonucleotides have a hydroxyl group on 2' carbon of their sugar subunit

Which of the following is effective against prion disease

Avoiding the consumption of brain tissue

Multiple gene products may be produced from single gene as a consequence of which genetic mechanism

Alternitive splicing

The presence of glucose affects the lac operon in which of the following ways

Reduces efficiency of RNA polymerase binding to promoter

A virus that contains DNA as genetic material requires which unique enzyme in order to replicate in a host cell

Reverse transcription

When bacteria are exposed to nutrient-poor conditions, they form a thick-walled structures that contain the chromosome and a small amount of cytoplasm. These structures are called

Endospores

On the outer surface of the plasma membrane there are marker molecules that identify the cell type. Often these molecules are

Carbohydrate chains on protein and or lipid

Tooth decay is the result of bacteria living in biofilms of the surface of the teeth the most common causative genus is

Streptococcus

The greatest expression of the lack Opteron occurs when lactose levels are______

High and glucose levels are low.