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10 Cards in this Set
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Group B StrepAgalactae
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Can cause neonatal secpticemia, meningitis, or pneumoniaCan have early/late onset (utero, birth or later)60% of colonized mothers give birth to colonized babiesBlood cultures, swabs, CSF find G+ cocciObstetric Complications: UTI's, Peurperal sepsis, Amnionitis, Endometriosis, wound infections
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Viridens Streptococci
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S. Salavarius, S. MitisCan cause disease when introduced to abnormal heart valves.Alpha hemolyticFound in Normal flora of upper respiratory tractMust be differentiated from S. Pneumnonia
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Lactic Streptococci
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Found in milkNot associated with diseaseStrep LacisStrep Cremoris
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Group D Enterococcus
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Enterococci-Streptococcus Gaecalis Hemolysis variable (mostly non-hemolytic)FibrinolyticProtein/Carb factors regulate adheranceBacteriocins: Inhibit competitive bacteriaFound in normal flora of intestinal tractCommon in pyelonephritis, wounds and subacute bacterial endocarditisResistant to antibiotics (VRE)Vancomycin Resistant Enterococcus -Mediated by R-PlasmidsRisk factors: Urinary or intravascular cathertization Capable of surviving high concentrations of bile and sodium chloride (Grew on MSA) 7(E. Faecalis colonize large intestine 10and urinary tract
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Beta Hemolytic Strep
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All contain a group specific C-carbohydrateSerological grouping (lancefields typing)Group A -S. PyogensGroup B -S. AlgalactaeGroup C -Pathogen of animals
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Streptolysins
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Streptolysins *Strep S_Stable/oxygen (hemolysis) *Strep O-Inactivated by ox.(stab agar) *Antigenic (ASO titer) Strep marker *Cardiotoxid & LeukocidalStreptokinase- Initiates fibrinolytic dissolution of fibrin clots.Hyaluronidase Depolymerizes connective tissueErythrogenic toxin Local redness/Scarlet feverM.Protien Found in cell wall -pilli
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Strep Throat
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signs/symptoms: red sore throat, white patches tonsils, swollen lymp nodes in neck, fever, headache (naus/vomit children sometimes)Transmission: Direct close contact-respiratory droplets (cough/sneeze) Rarely from milk/milk productsUntreated patients most infectious 2-3wks after onset.Incubation period before symptoms:2-4 days after exposurePatient no longer infectious after 24 hrs. of antibioticsDiagnosis: throat swabbed for culture or rapid strep test (10-20 min) culture usually 24-48 hrs. (neg cult=viral)
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Scarlet Fever
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occurs w/sore throat and rarely w/impetego or other strep infectionsfever/rash over upper body (may be all)Rash is fine, red, rough texture and blanches upon pressureBright red strawberry tongueskin can peel after recovery.Illness spread by same means as strep/treatment same too
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Strep Morpholoy and Physiology
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G+ Cocci in chainsColonies: very small convex / granularPhys: facultative anaerobes Fastidious nutritionally (require blood, AA &nucleic acid derivatives) Catalase negative Is not dissolved in 10% bile salt ENCAPSULATED Blood Agar: HEMOLYTIC
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Group A _ Strep. Pyogenes
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Bacitracin identifiesPharyngitis/Strep throatScarlet FeverSkin infections(Nec. Fa. flesh-eating)Bactermia, sepsis, strep toxic shock synd,Complications: Acute Rheumatic Feverand Poststrep. glomerulitis
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