Sterile/non Sterile Compounding

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sharps container

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used syringes should be discarded in this

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reconstitution

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process of mixing a liquid and powder together to form a suspension

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geometric dilution

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technique used in mixing two ingredients of unequal quantities; begin with smaller quantity ingredient and add equal amount of larger quantity- continue until mixed

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blending

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act of combining two substances together

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levigation

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titration of a powder drug with a solvent, in which the drug is insoluble with the solvent

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titration

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process of rubbing, grinding, or pulverizing a powder to create fine particles

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characteristics of an absorption base

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anhydrous, difficult to spread after applied, non-washable, and greasy

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emulsions can be compounded by

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dry gum

wet gum

beaker method

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USP 797 requires a laminar hood fan should be cleaned with

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70% isopropyl alcohol

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spatulation

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mixing powders using a spatula in a mortar, an ointment slab, or a plastic bag; it is a process used when ingredients may liquify on mixing

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thickening agent

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makes a suspension viscous or thicker

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emulsifier

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stabilizes an emulsion

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flocculating agent

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prevents the clumping together of particles

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mucilage

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a glue-like substance

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single-dose container

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single-unit container intended for parenteral use

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tight container

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protects the product from contaimination

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single-unit container

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designed to hold a quantity of product intended for administration as a single dose after the container is opened

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unit-dose container

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intended for administration other than by the parenteral route as a single drug directly from the container

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total parenteral nutrition consists of

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50% dextrose, 20% fat, and 10% amino acid

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elixer

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clear, sweetened, flavored hydroalcoholic solution containing water and alcohol that may or may not be medicated

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aromatic water

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solution of water-containing oils that have a smell and are volitile

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suspension

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two-phase system in which solid particles are dispersed in a liquid vehicle, which may be oral, topical, or injectable

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syrup

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an aqueous solution containing sucrose or sucrose substitutes

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emulsion

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dispersion that may be either water-in-oil or oil-in-water

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gel

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two-phase system containing an extremely fine solid particle that when mixed is difficult to distinguish between the two phases; semi-solid form

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lotions

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liquid for topical application that contains insoluble solids or liquids

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ointment

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a homogeneous, viscous, semi-solid preparation, most commonly a greasy, thick oil with a highly viscosity that is intended for external application to the skin or mucous membranes

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spirit

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an alcoholic or hydroalcoholic solution containing volatile aromatic ingredients

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tincture

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alcoholic or hydroalcoholic solution of pure chemicals or extracts

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pastille

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lozenge or troche

solid dosage forms with flavoring that dissolve in the mouth

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collodion

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topical dosage form that contains pyroxylin and is dissolved in alcohol and ether

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extract

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process by which active ingredients are removed from their source though the application of solvents

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dispersion

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contains a solute dispersed through a dispersin vehicle

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Hazardous Communication Standard

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OSHA created

all employees are entitled to be aware of the specific hazards associated during their employment

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info required on package label

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generic name of the drug

strength

dosage form

manufacturer's name/lot number

expiration date after repackaging

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HEPA filters must be certified every

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6 months

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laminar hood flows must be certified every

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6 months

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lumen

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opening of needle

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bevel

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angled tip of the needle, where the lumen is located

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hilt

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attaches to the hub of the barrel of the syringe

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shaft

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length of the needle

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sterile water for injection

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been sterilized but has no antimicrobial agents and can be used in parenteral solutions

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sterile water for irrigation

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been sterilized but contains no antimicrobial agents; it is used as an irrigating system

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pharmacy balance must be certified every

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12 months

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laminar flow hood air flow velocity must be

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90% linear feet/min (+/- 20%)

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radioactive yellow III

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highest radioactive concentration

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chemotherapeutic agents must be compounded in

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vertical laminar air-flow hood

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Final weight x % (expressed as dec) =

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Amount of active ingredient

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1 oz is how many tbsp?

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2 tbsp

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1 cup is how many oz?

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8 fl oz

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1 pint is how many cups?

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2 cups

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1 quart is how many pints?

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2 pt

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1 gal is how many qt?

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4 qt

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5F - 160 =

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9C

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How many grams is 1lb?

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454g

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Final volume * % =

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Amount of active ingredient needed

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Weight of substance/weight of equal volume of water =

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Specific gravity

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Initial strength x initial weight =

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Final strength x final weight

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final units w/w

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grams

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final units v/v

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mL

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final unit w/v

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mL

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final unit v/w

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grams

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How many mL in gal?

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3800

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Flow rate=

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Volume/time