Step 1 - Pharm - Teratogens

Front 1

Sulfonamides

Back 1

Kernicterus

Front 2

Aminoglycosides

Back 2

Ototoxicity

Front 3

Fluoroquinolones

Back 3

Cartilage damage

Front 4

Erythromycin

Back 4

Acute cholestatic hepatitis (in mother)

Front 5

Clarithromycin

Back 5

Embryotoxic

Front 6

Tetracyclines

Back 6

Discolored teeth, inhibited bone growth

Front 7

Ribavirin

Back 7

Teratogenic

Front 8

Griseofulvin

Back 8

Teratogenic

Front 9

Chloramphenicol

Back 9

Gray baby

Front 10

Alcohol

Back 10

Microcephaly, ASD, mental retardation

Front 11

Cocaine

Back 11

Microcephaly, renal agenesis, congenital heart disease

Front 12

Diethylstilbestrol

Back 12

Vaginal or cervical clear cell carcinoma, mullerian defects

Front 13

Phenytoin

Back 13

Nail and distal phalynx hypoplasia, cleft lip and/or palate

Front 14

Retinoic acid (distinct from vitamin A)

Back 14

Craniofacial defect, CNS defect, cardiovascular defect
(disrupts function of HOX gene)

Front 15

Thalidomide

Back 15

Amelia (absent limbs), phocomelia (seal-like limbs)

Front 16

Tobacco

Back 16

IUGR, low birth weight

Front 17

Valproate

Back 17

Neural tube defects

Front 18

Warfarin

Back 18

Nasal hypoplasia, agenesis of corpus callosum

Front 19

Leading cause of birth defects

Back 19

Alcohol

Front 20

Renal damage

Back 20

ACE inhibitors, AII receptor blockers

Front 21

Placental abruption

Back 21

Cocaine

Front 22

Cleft palate, cardiac abnormalities, spontaneous abortion

Back 22

Vitamin A excess

Front 23

Flipper limbs

Back 23

Thalidomide

Front 24

Bone deformities, fetal hemorrhage, abortion

Back 24

Warfarin

Front 25

Absence of digits

Back 25

Alkylating agents

Front 26

CN VIII toxicity

Back 26

Aminoglycosides

Front 27

Neural tube defects

Back 27

Folate antagonists

Front 28

Limb dislocation, heart and lung fistulas; mechanism may include inhibition of cell migration

Back 28

Alcohol