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5 Cards in this Set
- Front
- Back
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Tetracycline Mechanism |
Typewriter = actis on bacterial ribosome, inhibiting translation Paperjam = bacteriostatic 30 sec timer = reversibly bind to 30S ribosomal subunit Prism = broad spectrum Sewage pipe = eliminated fecally (useful in patient with renal failure and they need no dosage adjustment) |
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Tetracycline treats for |
No mercy pharoah = activity against MRSA Ticks = activity against tick borne bacteria (rickettsia, francisella, borrelia, Ehrilichia) Bruce the cow = activity against Brucella Squirrels with fleas = activity against Yersinia Clam seat = treats chlamydial cercicitis and urethritis Uterus shape = treats chlamydial Pelvic inflammatory disease Clam bra = treats chlamydial bronchitis and atypical pneumonia Cross country skier = atypical "walking" pneumonia from Mycoplasma White capped mountains = treats acne |
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Avoid these if using tetracylcines |
3 Medals. Ca2+, Mg2+, Fe2+ = multivalent cations (Calcium, Iron Magnesium) decrease absorption Those cations come from Milk, antacids, and ferrous sulfate |
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Tetracycline side effects |
Kid chewing on medal = causes tooth discoloration due to chelation effects Tarantula = taratogenic - deposits in fetal teeth and bone Mud pile = GI side effects (nausea, vomiting, diarrhea) Photographers = photosensitivity Fan cone = Fanconi syndrome (Type 2 RTA) associated with use of expired tetracyclines |
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Resistance to Tetracyclines |
Bike pump = resistance via efflux pumps (pump drug out of cell) |
