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9 Cards in this Set
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SIADH patho |
Incr water reabsorp in the loop of Henley |
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SIADH S&S |
Hyponatraemia causes HA, seizure, death Decr reflexes Hypothermia Edema N/V Decr UO |
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SIADH labs |
Hypo Na Low Serum Osmo High urine osmo Urine sodium >20 |
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DI due to? |
Lack of ADH from various causes : Central= pituitary or hypothalamus damage Nephrogenic= defect in renal tubules OR psych |
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DI Sx |
Volume depletion! Thirst Polyuria Decr LOC Incr Temp Tachy Hypotension |
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DI labs |
Hypernatremia Elevated BUN/ Cr Serum OSMO >290, Urine Osmo < 10 Urine Sp. gravity < 1.005 |
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DI tx |
Vasopressin aka ADH test: if central cause then UO will decrease as there wasn't enough ADH being produced. If doesn't, then is nephro cause. If no cause, MRI should be done |
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SIADH tx |
If Na> 120 then restrict fluids to 1,000mL If Na 110-120, w/o Sx, restrict to 500 mL. If <110 or SX, give isotonic or hypertonic IVF and lasix. Monitor K |
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DI tx |
If Na >150, give D5W slowly over 12-24h . When Na <150, chaise to 1/2 NS or 0.9 DDAVP aka Desmopressin aka syuthetiC vasopressin 1-4ug every 12-24h |
