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9 Cards in this Set
- Front
- Back
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All 11 Non essential AAs come from 4 Major precursors, what are they, and where do they come from? |
3-Phosphoglycerate (glycolysis) Pyruvate ( Glycolysis) Alpha-Ketoglutarate (Krebs) Oxaloacetate (Krebs)
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how is aspartate made in the cell? |
Glu + Oaa --> Asp + A-KG |
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What is the major intermediate formed during Glutamine Sythesis, and which enzyme catalyzes this reaction? Is ATP invested? |
Gamma- Glutamyl Phosphate. Glutamine synthetase. Yes, 1 ATP equiv. |
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What is the major intermediate formed during Asparagine synthesis, what enzyme catalyzes this reaction? Is ATP used? |
it is an Acyl- Adenylate intermediate (has AMP attached). Catalyzed by Asparagine sythetase. Requires ATP. |
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What is the order of products from 3-Phosphoglycerate to Serine? |
3-Phosphoglycerate, 3-phosphohydroxypyruvat, 3-phosphoserine, Serine |
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What type of enzyme cleaves off a phosphate group and leaves a hydroxyl group? |
a phosphatase. |
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What enzyme catalyzes the production of glycine from Serine? |
Serine hydroxymethyl-trasnferase. |
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What cofactors are required for Serine Hydroxymethyl-transferase to function? |
THF (or H4 Folate), and PLP (Pyridoxal Phosphate) |
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What happens to the Oxygen on Serine after it gets converted into glycine? |
The oxygen becomes incorporated into H2O |
