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86 Cards in this Set

  • Front
  • Back
Follow up for low grade dysplasia with barret's esophagus?
yearly endoscopy with four quadrant biopsies every 2cm along the length of Barrett's segment for low grade
Follow up for high grade dysplasia with barret's esophagus?
every 3 months if focal; if multifocal needs intervention
Treatment options of achalasia
Botulin 85% but recurs
Dilation 90% not good in young
Myotomy + fundoplication 95%
LGIB Surgery
subtotal colectomy b/c segmental resections have 75% rebleed with 50% mortality
Rates of bleeding detected by angio vs bleeding scan
1.0ml/hr vs 0.1ml/hr
MCC of death in FAP
duodenal adenoCA
Management of duodenal polyps in FAP showing only dysplasia
Whipple
Risk of malignancy in UC
0.1-0.2%/year
2% @ 10 years
8% @ 20yrs
20% @ 30
Rectal NETS
10% of all GI NETs
more frequent and better prog than colon
usually <1cm (can be removed endoscopically)
<2cm have >70% mets
less likely to secrete vasoacitve
Most common appendiceal malignancy
1) Mucinous adenoCA
2) Carcinoid
When is R hemicolectomy indicated in appendiceal malignancies?
All non NET and NET >2cm
Location and pathophysiology of gastric ulcers
Type 1 - near angularis incisura on lesser curve
Type 2 - a/w duodenal ulcer
Type 3 - prepyloric
Type 4 - GE junction
Gastric CA with + nodes should receive...
fluorocil + XRT
what type of fistulas can be managed with simple fistulotomy?
intersphinteric
contraindications to neostigmine
Bradycardia
Renal impairment
History of bronchospasm
Reasons for recurrent duodenal ulcer s/p highly selective vagotomy
Spares branches to liver and biliary system
may miss criminal nerve of Grassi (right posterior vagus nerve)
Anal margin vs anal canal CA
WLE vs Nigro protocol
gallbladder polyps
remove if
>10 mm
symptomatic or
>50 yo
Co-localization theory of pancreatitis
cathepsin B mediated intra-acinar cell activation of digestive enzymes
management of pancreatic pseudocysts
2% of acute pancreatitis
85% single
leave alone if asymptomatic or not growing for at least 6-12 weeks (40% will spontaneous resolution)
to allow for maturation of wall
Pancreatic solid cystic tumors
almost exclusively in young
women
usually asymptomatic
pancreatic resxn TOC
MC tumor of liver
hemangioma
usually incidentally found
<5cm usually
homogeneous, hyperechoic, well circumscribed ass with posterior acoustic enhancement
CT description of hemangioma
hypoattenuation
early peripheral enhancement
progressive opacification toward center
complete isoattenuation fill in occurring
Best imaging modality for hemangioma
MRI
treatent of desmoid tumors
sulindac or tamoxifen
Gene mutation in FAP
APC
Description of FNH lesion
well circumscribed, nonencapsulated, nodular cirrhotic like mass
fibrous stellate central scar
early enhancement with washout on delayed
Where are carcinoid derived from?
amine precursor uptake and decarboxylation (APUD) neural crest (ectoderm)
Intraductal papillary mucinous neoplasia of pancreas
premalignant
15% have jaundice
hallmark is thick mucin *multiple cysts and ducts
management of isolated gastric varices
splenectomy if splenic vein thromobosis is cause
Spigelian hernia
usually b/n umbilicus and arcuate line
Howship-Romberg sign
50% present in obturator hernia
pain along medial thigh to knee
flexion of hip exacerbates pain
Richter's hernia
partial protrusion of antimesenteric intestine
HCC
initially low attenuation
enhance brightly with contrast
become hypodense on delayed images
hepatic adenoma
early peripheral enhancement
centripetal filling
hyperintense on T2
role of octreotide in carcinoid syndrome
controls diarrhea but does not prevent progression of carcinoid valvular dz
Management of Zenker's vs epiphrenic divertculum
esophageal myotomy is on the same side of diverticulectomy in Zenker's and opposite in epiphrenic
Studies needed for GERD workup
Endoscopy +/- biopsy
pH probe
Manometry
all patients with Schatzki's rings have
sliding hiatal hernia
Follow up for Barrett's s/p Nissen
lifetime EGD
Three approaches to esophagectomy
Transhiatal
Ivor Lewis
3 hole esophagectomy
all need pyloromyotomy
chemo for esophageal cancer
5FU and cisplatin
Dysphagia with smooth filling defect and intact mucosa with normal histology
GIST --> enucleation if >5cm or symptomatic
Management of caustic esophageal injury
no NGT, NPO, IVF, antibx
Endoscopy
Serial CXR/AXRs
Gastro->barium swallow on HD 2-3 for 2nd/3rd degree burns
MC site of esophageal perforation
cricopharyngeus
Nutcracker vs DES
single vs multiple prolonged, high amplitude contractions
Gastrografin vs Barium in chest and abdomen
Barium (inert) harmful to lungs so gastrografin first
Management of esophageal perforations
if not contained/systemic --> depends on time of dx/contamination
<24 hrs/clean --> primary repair, longitudinal myotomy, drains, buttress repair with flaps (pleura, pericardium, intercostal mm, omentum)
POD 10 gastro/barium swallow
For sick pts --> cervical esophagostomy, mediastinal washout, chest tubes, later G/J tube and esophagectomy
Type I gastric Carcinoids
70-80%
Chronic atrophic gastritis
Pernicious anemia
Hypergastrinemia --> trophic effect on ECL cells (oxyntic fundic mucosa)
F>M 2cm
Multicentric
<5% mets
Type II gastric carcinoids
Least common
A/W hypergastrinemia of ZE syndrome/MEN 1
M:F
Multicentric
<2cm
10% mets
Type III gastric carcinoids
15-20%
Sporadic
No hypergastrinemia
Most aggressive
Solitary
>5cm
what do all gastric carcinoids stain for?
Chromogranin A
What imaging modality is useful gastric carcinoids?
Somatostatin receptor scintigraphy
Percentage of gastric carcinoids that p/w carcinoid syndrome
10%
treat with somatostatin
Effect of PPIs in UGIB
prior to endoscopy reduces stigmata of recent hemorrhage but do NOT reduce mortality, re-bleeding, or need for surgery
Where is bleeding duodenal ulcer usually?
posterior in 1st portion (3 vessel ligations)
What do you have to do with truncal vagotomy?
pyloroplasty
HSV vs truncal vagotomy
decreased gastric atony, alkaline reflux, gastritis, dumping, diarrhea
Incidence of biliary injuries in cholecystectomies
0.2-2%
Incidence of Duct of Luschka injuries
0.04-0.2%
Characteristics of colonic polyps that require rxn
Poor diff
Haggitt level 4 invasion
<2mm margin
All sessile
Pedunculated polyps with stalk invasion
Presentation of postpolypectomy syndrome
pain, fever, high WBC
w/n 12 hrs-days
no free air
focal thickening of colonic wall
Gastric carcinoid incidence of all gastric CA and all carcinoids
2-5% of all gastric CA and 1-3% of all carcinoids
How do gastric carcinoids usually present?
abdominal pain or GI bleeding
5YRS for Type I-III gastric carcinoids
90>75>50
% of colon CA that p/w obstruction
15%
% of colon CA that are R sided
25%
Colonic stenting
FDA approved
>90% success
1/2 the mortality of sx
AE of colonic stenting
Perforation (4%)
Stent migration
Re-obstruction 10%
Pain & rectal tenesmus
Bleeding
Long term survival in stenting vs emergency sx for obstructing colonic CA
no difference
Epiphrenic diverticula
- Rare malignant mucosal transformation 0.3-3%
- A/w esophageal motility disorder (pulsion)
- Distal third of esophagus
- A/w mechanical obstruction of LES
- Dysphagia, regurgitation, reflux, chest pain, halitosis
- 45% risk of aspiration
SBO more frequent in retro or antecolic
retro
Early vs Late SBO s/p gastric bypass
nternal hernias caused by jejuj's mesenteric defects typically occur late

Early SBO usually @ jej-jej
3 types of bile acid malabsorption
Type I most common; ileal disease/rxn
Type II idiopathic
Type III s/p vagotomy or cholecystectomy
Acute tachycardia & SOB s/p bariatric surgery
usually normal exam and false negative CT
What studies do you need before operating on GERD
24H pH
Esophagoscopy
UGI
Esophageal manometry (partial vs 360 wrap)
gastric emptying studies in DM
MC complication of EGD
:Hypoxia (1.6%)
MC benign esophageal neoplasm
Leiomyoma
- Peak in 3rd-5th decades of life
- Distal 2/3 of esophagus (80% muscularis propria)
- Dysphagia, pain, weight loss
- C-KIT negative
- Mobile, nonobstructive mass projecting into lumen with normal overlying mucosa
- TOC for 2cm - thorascopic enucleation
Most common GI carcinoid to produce malignant carcinoid syndrome
ileum
Where do carcinoid tumors arise from?
enterochromaffin cells (kulchitsky)
Where do GIST tumors arise from?
Interstitial cells of Cajal
Most common symptom in carcinoid syndrome?
Flushing
Surgical management in adult intussussception
resection, lymphadenectomy and anastomosis
Malrotation is found in 20% of people with?
congenital diaphragmatic hernia
Treatment for Crohn's perianal abscess above anal sphincter
Surgical drainage
seton
antbix
Peutz-Jegher's polyps are what type?
hamartomas - not premalignant