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26 Cards in this Set

  • Front
  • Back
Cartilage consists of cells called ____ and an extracellular matrix composed of ____ and _______.
chondrocytes, fibers, ground substance
The principle macromolecules found in all cartliage are ___, ___, ____ and _____.
collagen, hyaluronic acid, glycoproteins, proteoglycans
The firmness of cartilage is produced by the electrostatic interactions between ____ fibers and the ____ side chains of matrix ____.
collagen, glycosaminoglycans, proteoglycans
The 3 types of cartilage are ____, ____ and ____.
hyaline, elastic, fibrocartilage
____ cartilage that covers the surface of the bones of moveable joints, is devoid of _____ and gets oxygen and nutrients through diffusion from ____.
articular, perichondrium, synovial fluids
___ cartilage is the most common common, as well as the temporary skeleton of the embryo.
In routine histology preperations of hyaline cartilage collagen is not visible because it is in the form of ____ and has the same ____.
fibrils, refractive index of its ground substance
The bulk collagen in hyaline cartilage is type ___, while type ___ regulates size, type ___ enhances fibril binding with proteoglycans, and type X _____.
II, XI, IX, is involved in 3D arrangement
Proteoglycans of ground substance contain 3 types of GAGs, ____, ____, and ____, which are linked to _____ acid to form ____.
chondroitin 4-sulfate, chondroitin 6-sulfate, keratin sulfate, hyaluronic acid, proteoglycan aggregates
____ mediates the binding of chondrocytes to the extracellular matrix by binding to GAGs and collagen type II.
Except in the _____ of joints, all hyaline cartilage is covered by the _____.
articular cartilage, perchondrium
Solvation water bound to the negative charges of ____ act as a ____.
glycosaminoglycans, shock absorber
Around the lacunae, chondrocytes have a higher concentration of ____ and less ____. This area is called the ____.
sulfated proteoglycans, collagen, territoral or capsular matrix
The area between lacunae that stain less heavily
interterritorial matrix
Pericondrium is rich in collagen type ___ and contain _____, with ____ in the inner layer that differentiate into chondrocytes.
I, fibroblasts, chondroblasts
____ groups are formed from mitotic division of a single chondrocyte into upto 8 cells.
Chondrocytes have well developed ___ and ___, and produce ____, ___, _____ , and adhesive ____.
RER, Golgi, Collagen II, GAGs, proteoglycans, glycoproteins
Chondrocyte synthesis of sulfated GAGs are stimulated by ____, ___, and ___, and slowed by ___, ___, and ____.
growth hormone, testosterone, thyroxine, cortisone, hydrocortisone, estradiol
Cartilage growth depends on growth hormone _____, which stimulates synthesis of ____ in the liver that acts directly on the cells.
somatotropin, somatomedin C
____ growth results from the mitotic division of preexisting chondrocytes, and ___ growth results from the differentiation of perichondrial cells.
interstial, appositional
___ cartilage growth occurs in early phases of cartilage development, and in the epiphyseal plates of long bones within ____ cartilage.
interstitial, articular
___ cartilage is identical to hyaline cartilage except it contains elastin fibers.
___ cartilage is located in the pinna of the ear, external and internal auditory tubes, epiglottis and larynx.
___ is a tissue intermediate between dense CT and hyaline cartilate
Fibrocartilage does not have a ____ and is predominatly composed of collagen type ____.
perichondrium, I
____ carilage is located in intervertebral disc, symphysis pubis and the menisci of knee joint.