Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
32 Cards in this Set
- Front
- Back
Fibrinolytic |
alteplase |
|
Side effects of heparin |
bleeding thrombocytopenia osteoporosis skin necrosis hypersensitivity reaction hyperkalemia hypoaldosteronism |
|
Monitoring of heparin |
aPTT Factor Xa |
|
Antidote of heparin |
protamone sulfate |
|
Low molecular weight heparin(enoxaparin, lovenox) |
longer half life more predictable lower bleeding risks |
|
Aspirin |
recommended 24-48 hours post stroke If tPA, hold 24 hrs 325mg po or rectal -persist in system for 7-10days -don't take with NSAIDs |
|
Aspirin and dypiridamole |
aggrenox Most common side dffect headache due to vasodilation |
|
Warfarin |
Vitamin k antagonist stays in the system 2-5 days Monitor PT/INR (2.5-4.2) |
|
Complications of warfarin |
warfarin necrosis osteoporosis purple toe syndrome(3-8wks treatment) |
|
Dibigatran(Pradaxa) |
direct thrombin inhibitor no monitoring no antidote |
|
Rivaroxaban(Xarelto) |
half life: 5-9hours cleared renal ,hepatic and fecal |
|
Apixaban(Eliquis) |
half life: 8-15hrs direct Xa inhibitor |
|
Statins |
decrease total cholesterol stabilizes plaque anti inflammatory effects Don't take with grapefruit juice |
|
Adverse side effect of clevidipine |
AF Pancreatitis Allergic reaction to eggs and soy |
|
Nitroprusside |
direct vasodilator coronary artery steal( steals oxygen from ischemic areas to non ischemic are Methemoglobina- can't carry oxygen |
|
Dopamine |
alpha stimulant |
|
Mannitol |
os.otic diuretic monitor serum and sodium osmolality |
|
Lacosamide |
Sodium channel blocker side effect-diplopia and renal stones |
|
Only drug approved for primary prevention |
aspirin |
|
reversal of warfarin |
vitamin K FFP |
|
Rivarxaban(xarelto) |
only direct thrombin inhibitor you can crushed |
|
tPA |
within 10mins of completion, 80percent of drug is out of the system |
|
Goal INR with warfarin |
2.5-4.2 |
|
Adverse reaction of tPA |
Angioedema Anaphylaxis ICH |
|
adverse reaction of hydralazine |
reflex tachycardia |
|
Glycemic control recommendation |
140-180 |
|
Baclofen withdrawal syndrome |
fever rash seizure cardiac instability |
|
Antispasmodics |
Tizanidine baclofen dantrolene botox |
|
antidepressant |
may take 4-6 weeks to feel full effect |
|
neurostimulants |
used post stroke to accelerate and improve motor recovery or cognitive recovery |
|
nicardipine |
titrable 2.5mg every 15minutes |
|
adverse reaction of valproic |
increased ammonia |