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14 Cards in this Set

  • Front
  • Back
The peak age of onset of shcizophrenia is ________ for men and _________ for women.
15-25 years old for men
25-35 years for women

schizophrenia occurs equally in men and women, all cultures and all ethnic groups studied
Symptoms of schizophrenia can be classified as positive or negative. Describe the classification categories and name examples of symptoms in each.
Positive symptoms = things additional to expected behavior (delusions, hallucinations, agitation, talkativeness) ; these respond well to both traditional and atypical antipsychotic agents.

Negative symptoms = things missing from expected behavior (lack of motivation, social withdrawal, flattened affect, cognitive disturbances, poor grooming, impoverished speech content); these respond better to atypical (rather than typical) antipsychotic agents.
Patients with [ positive / negative ] symptoms respond well to traditional and atypical antipsychotic agents whereas patients with [ positive / negative ] symptoms respond better to atypical than to traditional antipsychotics.
Positive symptoms = both typical and atypical

Negative symptoms = moreso to atypical
Patients with [ positive / negative ] symptoms have more neuroanatomic and metabolic abnormalities than those with predominantly the other kind of symptoms.
Patients with NEGATIVE symptoms (lack of motivation, social withdrawal, flattened affect, cognitive disturbances, poor grooming, impoverished speech content) usually have more neuroanatomic and metabolic abnormalities
Schizophrenia ha three phases: prodromal, active and residual phase. Describe each.
Prodromal : signs and symptoms occur prior to the first psychotic episode and include avoidance of social activities; physical complaints; and new interest in religion, the occult, or philosophy.
ACTIVE PHASE: patient loses touch with reality. Disorders of perception, thought content, thought process, and form of thought occur during an acute psychotic episode.
RESIDUAL PHASE: time between psychotic episodes where the patient is in touch with reality but does NOT behave normally. Typically characterized by negative symptoms.
What is FALSE about the prognosis of schizophrenia?
A. Involves repeated psychotic episodes and a chronic, downhill course over years. The illness often stabilizes in midlife.
B. Suicide is common- more than 50% attempt suicide, and 10% of those die in the attempt
C. The prognosis is better and suicide risk is lower if the patient is older at onset of illness, is married, has social relationships.
D. The prognosis is worse and suicide risk higher if the patient has mood symptoms.
D. is FALSE. It actually is associated with a better prognosis.
True or False:
No social or environmental factor causes schizophrenia.
TRUE.

However, there is a "downward drift" hypothesis which says that patients with schizophrenia tend to drift down the SES as a result of their social deficits and are thus found in lower SES groups.
Anatomical neural pathology of someone with schizophrenia includes
A. abnormalities of the frontal lobes - how so?
B. lateral and third ventricle size change - how so?
C. limbic structure volume change - how so?
A. abnormalities of the frontal lobes - DECREASED USE OF GLUCOSE IN FRONTAL LOBES UPON PET SCAN
B. lateral and third ventricle size change - ENLARGEMENT, ABNORMAL CEREBRAL SYMMETRY
C. limbic structure volume change - DECREASED VOLUME OF LIMBIC STRUCTURES
Which of the following is NOT implicated in neurotransmitter abnormalities present in schizophrenia?
A. ACh
B. Dopamine
C. Glutamate
D. Serotonin
NOT implicated in schizophrenia is : A. ACh

Excessive dopamine hypothesis of schizophrenia,
Serotonin hyperactivity is (since hallucinogens that increase serotonin concentrations can cause psychotic symptoms),
Glutamate is also implicated
Psychotic disorders are ALL characterized at some point during their course by ...... Name other psychotic disorders besides schizophrenia.
a loss of touch with reality!

Brief psychotic disorder: psychotic symptoms lasting more than one day but less than one month.
Schizophreniform disorder : psychotic and residual symptoms lasting 1-6 months
Schizoaffective disorder : symptoms of a mood disorder plus psychotic symptoms
Delusional disorder : fixed persistent delusions
Shared psychotic disorder : development of delusions in a person in a close relationship with someone with delusional disorder
Symptoms of schizophrenia include disorders of perception, thought content, thought process and form of thought. Give examples of symptoms of each.
Impaired abstraction ability (probs discerning the essential qualities of objects or relationships) and magical thinking (belief that thoughts affect the course of events) are examples of disorder of __________ in schizophrenics.
A. Perception
B. Thought content
C. Thought process
D. Form of thought
C. Thought process
C. Thought process
Delusions (false belief not shared by others) and the idea of reference (false belief of being referred to by others) are examples of disorder of __________ in schizophrenics.
A. Perception
B. Thought content
C. Thought process
D. Form of thought
B. Thought content
B. Thought content
Loose associations (shift of ideas from one subject to another in an unrelated way), neologisms (inventing new words), and tangentiality (getting further away from the point as speaking continues) are examples of disorder of __________ in schizophrenics.
A. Perception
B. Thought content
C. Thought process
D. Form of thought
D. Form of thought
D. Form of thought