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14 Cards in this Set

  • Front
  • Back
Acinic cell carcinoma
Acinic cell carcinoma
1-3% of salivary gland tumors; #2 childhood salivary gland malignancy after mucoepidermoid carcinoma
Adenoid cystic carcinoma. Note small cells, with bland nuclear features, forming a pseudoglandular space. This space contains a homogeneous, metachromatically staining hyaline globule.
acinic cell carcinoma
Mucoepidermoid Carcinoma (MEC). MEC is the most common malignant salivary gland
tumor in both children and adults. It most commonly occurs in the 5th decade and is more common in
females (3:2). This tumor is characterized by epidermoid, intermediate, and mucus cells. The most
important diagnostic activity is to identify intracellular mucin (this may be very scarce).
Oncocytoma of the Parotid. Oncocytomas are rare salivary gland tumors (1%). When
present, they are found in the parotid gland in 80-90% of cases. In general they have the same findings of
oncocytomas in other locations, and contain numerous mitochondria in the cytoplasm.
Pleomorphic Adenoma (PA). PAs are characterized by a remarkable amount of histologic
heterogeneity. It is composed of varying proportions of epithelial ductal structures, myoepithelial cell, and
mesenchymal stroma (any portion may predominate). PAs are the most common salivary gland tumor (F >
M) comprising 54-76% of salivary gland neoplasms. They are most commonly diagnosed between the age
of 30 and 40 years old. (
Sclerosing Sialoadenitis. The lobular architecture of the salivary gland is retained at low
power, but the acinar structures have been destroyed by the inflammatory process leaving only ductal
elements with a fibrotic background. This process is almost identical to the appearance of chronic
pancreatitis.
Bilateral acoustic schwannomas of the eighth cranial nerve is associated with which of the
following disorders:
Bilateral acoustic schwannomas is associated with NF, type 2. The schwannomas are
characterized by antoni A (hypercellular) and antoni B (hypocellular) areas, verocay bodies (palisading of
nuclei), and S-100 posivitity.
How often is acinic cell carcinoma is found in the parotid gland?
Acinic cell carcinoma is located in the parotid gland approximately 80% of the time. It is found
in the submandibular gland 4% of the time and the sublingual gland 1% of the time.
congenital granular cell epulis
Congenital epulis is S-100 negative, which differentiates it
from an adult granular cell tumor.
Bilateral acoustic schwannomas of the eighth cranial nerve is associated with which of the
following disorders:
Bilateral acoustic schwannomas is associated with NF, type 2. The schwannomas are
characterized by antoni A (hypercellular) and antoni B (hypocellular) areas, verocay bodies (palisading of
nuclei), and S-100 posivitity.
How often is acinic cell carcinoma is found in the parotid gland?
Acinic cell carcinoma is located in the parotid gland approximately 80% of the time. It is found
in the submandibular gland 4% of the time and the sublingual gland 1% of the time.
congenital granular cell epulis
Congenital epulis is S-100 negative, which differentiates it
from an adult granular cell tumor.