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35 Cards in this Set
- Front
- Back
T/F
The granulosa layer of a secondary follicle responds to LH. |
False, the theca interna responds to LH.
The granulosa layer of secondary follicle produces LH receptors but not not itself respond to LH. |
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T/F
The theca externa is highly vascularized. |
False, the theca INTERNA is highly vascularized.
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T/F
The theca interna is separated from the theca externa by a basal lamina |
False, the theca interna is separated from the granulosa layer by a basal lamina.
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T/F
The secondary follicle contains a secondary oocyte. |
False, secondary follicle contains a primary oocyte
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T/F
The granulosa layer converts androstenedione to estrogens. |
TRUE!!!!
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T/F
FSH stimulates the primordial follicles to develop. |
False, it it not dependent upon FSH
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T/F
FSH stimulates the production of progesterone in the corpus luteum. |
False
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T/F
The corpus luteum responds to estrogen stimulation. |
False, corpus luteum responds to LH or hCG
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T/F
Inhibin blocks FSH secretion |
True!
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T/F
LH stimulates proliferation of the granulosa cells in the primary follicle. |
False, activin stimulates proliferation of the granulosa cells in the primary follicle.
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T/F
Medullary region of ovary is rich in blood vessels and CT. |
True
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What tissue gives rise to follicular cells?
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Germinal epithelium in the cortical region of the ovary
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What secretes OMI (oocyte maturation inhibitor)?
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Follicular cells
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Primordial follicle has a balbiani body and a annulate lamellae. What are these things?
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Balbiani body sits near the nucleus and is composed of golgi membranes, E.R., mitochondria and lysosomes.
Annulate lamellae are found in ooplasm and resemble profiles of nuclear envelope |
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A primary follicle has follicular cells, theca folliculi, and filopodia. What is the difference between a unilaminar and multilaminar primary follicle?
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Unilaminar primary follicle has a single follicular cell layer.
Multilaminar primary follicle has a stratified layer of follicular cells. |
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Where are cortical granules and what do they do?
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They are found just beneath the plasma membrane of the oocyte and contain proteolytic enzymes that are released during fertilization to prevent polyspermy.
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What two layers do the theca folliculi differentiate into?
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1.) Theca interna
2.)Theca externa |
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Which thecal layer has LH receptors and can produce androstenedione?
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Theca interna
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Which thecal layer is highly vascularized with cuboidal epithelium?
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Theca interna
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Which thecal layer is mainly smooth muscle cells and collagen fibers?
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Theca externa
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Which follucular phases depends on FSH?
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Only secondary and Mature Graafian follicles.
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A secondary follicle is recognized by fluid filled spaces called __________.
What substances are in this fluid? |
Antrum.
The fluid (liquor folliculi) is an exudate of plasma with GAGs, proteoglycans and hormones |
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Which hormones is responsible for increasing the number of granulosa cells and the number of intercellular spaces?
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FSH
Granulosa cells have FSH receptors (they also have LH receptors after ovulation to make progesterone) |
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When there is a single antrum space, what type of follicle is this?
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Mature Graafian Follicle (preovulatory follicle)
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What is a cumulus oophorus and which follicle is it associated with?
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part of the granulosa which surrounds the oocyte but is also continuous with the granulosa surrouding the follicle (forms an oocyte bridge).
Found in a mature graafian follicle |
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What thecal layer does LH stimulate?
What are they products? |
LH stimulates theca interna cells to make androstenedione.
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What stimulates granulosa cells to use androgens to make estrogen?
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FSH stimulates granulosa cells to make aromatase; which catalyzes androgens to estrogens.
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What causes the LH surge?
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immediately before ovulation, estrogen begins to become a positive feedback molecule causing the release of EVEN MORE LH, results in an LH surge.
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List the sequence of events occuring after LH surge. (5 things).
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1.) oocyte continues through meiosis 1
2.) formation of secondary oocyte and polar body 3.) secondary oocyte is arrested in metaphase of M2 4.) ovulation of secondary oocyte on dya 14 5.) Formation of the corpus leuteum. |
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*Don't know if this is correct but....
other than the LH surge, the increase of estrogen b4 ovulation also causes .... |
negative feedback on FSH release from pituitary.
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Region of the ovary that is blanched and avascular before ovulation is known as the_______.
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Stigma
This is the area where the oocyte ruptures into the abdomen. |
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After ovulation, the remnant of the graafian follicle forms a blood clot and is called the __________.
How is this clot removed? |
Corpus hemorrhagicum.
Phagocytes will remove the clot. |
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High LH levels will turn a corpus hemorrhagicum into a corpus luteum. The organ is highly vascularized and composed of what two cell types?
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Granulosa-lutein cells and Theca-lutein cells
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After ovulation, corpus leutum granulosa lutein cells will begin synthesizing TONS of what hormone?
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Progesterone.
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Progesterone and estrogen secreted by the corpus luteum will have a negative feedback on what?
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Progesterone inhibits LH
Estrogen inhibits FSH (Low FSH will prevent a second ovulation!!!) |