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25 Cards in this Set
- Front
- Back
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what does pANCA indicate?
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microscopic polyangitis
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what drug is used to prevent uric acid stones with tumor lysis syndrome?
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allpurinol
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what do you see on microscopy with gout? +/- birefringence?
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needle-shaped crystals with (-) birefringence
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what do you see on microscopy with pseudogout? +/- birefringence?
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rhomboid-shaped crystals with (+) birefringence
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what types of substances/drugs can cause acute gouty flare-ups?
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due to substances rich in purines, i.e. alcohol and use of thiazide diuretics
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what is the main treatment for acute gout?
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indomethicin
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how does dermatomyositis present?
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proximal muscle weakness with Gottron papules over the knuckles, heliotrope purple rash around the eyes; may also see calcifications in the subcutaneous fatty tissue
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what labs are elevated with dermatomyositis?
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elevated CK and aldolase
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how do you diagnose dermatomyositis?
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muscle biopsy
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how do you treat dermatomyositis?
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corticosteroids
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what two test are highly specific for SLE?
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anti-dsDNA and anti-Smith
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vascular thrombosis + multiple miscarriages = ?? and what test may be false-positive?
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likely anti-phospholipid syndrome, may have false-positive VDRL
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how do you diagnose polyarteritis nodosa? what test is elevated in 30% of cases?
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diagnose via tissue biopsy, pANCA is often elevated
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a positive cANCA indicates what?
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Wegner's granulomatosis
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what disease is highly associated with polyarteritis nodosa you must work them up for?
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Hepatitis B and C
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patient >50 with morning stiffness of the proximal musculature with fatigue, depression and low-grade fever
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polymyalgia rheumatica
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polymyalgia rheumatica
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treat with corticosteroids
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treatment for pregnant woman with RA flare-up
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oral prednisone
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young male with chronic back stiffness, photosensitivity, oral ulcerations and fatigue
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ankylosing spondylitis
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what antigen is positive with ankylosing spondylitis?
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HLA-B27
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what diseases is HLA-B27 correlated with?
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ankylosing spondylitis, Reiters syndrome, acute anterior uveitis, iritis, Behcet's disease, psoriatic arthritis, IBD
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what is Behcet's syndrome?
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vasculitis leading to oral ulcers, along with possible genital ulcers, skin lesions, eye inflammation
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what should suspect in a patient with genital ulcers, oral ulcers and uveitis?
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must suspect Behcet's syndrome
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treatment for Behcets syndrome
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corticosteroids
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what do the T-scores indicate?
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-1 to -2.5 = osteopenia
<-2.5 = osteoporosis |
