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48 Cards in this Set

  • Front
  • Back
Diphenhydramine
mech
H1 blocker
1st generation
diphenhydramine
use
allergy
motion sickness
insomnia
diphenyhydramine
se
sedation
antimuscarinic
anti-alpha-adrenergic
dimenhydrinate
mech
h1 blocker
1st generation
dimenhydrinate
use
allergy
motion sickness
sleep aid
dimenhydrinate
se
sedation
antimuscarinic
anti alpha adrenergic
chlorpheniramine
mech
h1 blocker
1st generation
chlorpheniramine
use
allergy
motion sickness
insomnia
chlorpheniramine
se
sedation
antimuscarinic
anti alpha adrenergic
loratadine
mech
h1 blocker
2nd generation
loratadine
use
allergy
2nd gen h1 blocker
se
less sedating than 1st gens
b/c less cns entry
fexofenadine
mech
h1 blocker
2nd gen
fexofenadine
use
allergy
desloratadine
mech
h1 blocker
2nd gen
desloratadine
use
allergy
cetirizine
mech
2nd gen h1 blocker
cetirizine
use
allergy
isoproterenol for resp
mech
beta-agonist (nonspecific)
relax bronchial smooth m (b2)
isoproterenol (resp)
use
asthma
isoproternol (resp)
se
tachycardia (b1 agonist)
albuterol
mech
beta 2 agonist
relax bronchial smooth m.
albuterol
use
acute asthma
salmeterol
mech
b2 agonist
dilate bronchial smooth m.
salmeterol
use
acute asthma
salmeterol
se
tremor
arrythmia
theophylline
mech
methylxanthine
bronchodilation
inhibit phophodiesterase
less camp breakdown
blocks adenosine (bronchonconstrictor)
theophylline
use
limited use b/c lotta se
asthma
theophylline
se
cardiotox
neurotox
ipratropium
mech
muscarinic blocker
broncho m. relaxer
ipratropium
use
asthma
COPD
cromolyn
mech
steroid
prevent mast cell stuff release
cromolyn
use
only asthma prophylatic!
not effective for acute
beclomethasone (resp)
mech
inhibit cytokines (almost all!)
inactivate NF-kappa B
-> transcirption factor makes TNF alpha et al
beclomethasone (resp)
use
1st line tx for chronic asthma
prednisone (resp)
mech
inactivate NF-kappa B
transcription factor for making TNF alpha et al
prednisone (rep)
use
chronic asthma 1st line therapy
zileuton (resp)
mech
5-lipoxygenase pathway inhibitor
blocks arachidonic acid conversion to leukotrienes
zileuton (resp)
use
asthma
zafirlukast (resp)
mech
leukotriene blocker
zafirlukast-resp
use
asthma especially aspriin-induced
montelukast
mech
leukotriene antagonist
montelukast
use
asthma especially aspirin induced
guafinesin
mech
robitussin
expectorant
remove excess sputum w/o suppressing cough reflex
need lots though
n-acetylcysteine - resp
mech
expectorant
mucolytic
loosen mucus plugs
n-acetylcysteine - resp
use
cystic fibrosis
acetaminophen overdose
bosentan
mech
endothelin-1 blocker
less pulmonary vessel resistance
bosentan
use
pulmonary htn