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15 Cards in this Set
- Front
- Back
Hydrostatic pressure inside the glomerular capillaries →
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Promotes filtration
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Hydrostatic pressure in Bowman’s capsule outside the capillaries →
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Opposes filtration
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Colloid osmotic pressure of the glomerular capillary plasma proteins →
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Opposes filtration
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Colloid osmotic pressure of the proteins in Bowman’s capsule →
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Promotes filtration
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Increase in capillary hydrostatic pressure
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= increase filtration
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Increase in oncotic
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= decrease filtration
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As plasma albumin drops
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= increase GFR
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GFR is proportional to
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renal blood flow, which is regulated at a relatively constant rate over a wide range of perfusion pressures due to autoregulation (GFR should stay relatively constant so the tubules are not dealing with widely varying amounts of fluid to reabsorb)
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GFR is also proportional to
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the number of functioning nephrons
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GFR is regulated by....
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Starling forces, in particular by the relative resistance across afferent and efferent arterioles controlling Pcap
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Increased afferent arteriole resistance....
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.....decreases renal blood flow AND decreases GFR; increased efferent arteriole resistance decreases renal blood flow but maintains GFR
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GFR is accurately measured by a compound called insulin. The insulin is infused intravenously and appearance is measured in the urine.
The clearance formula used is: |
The clearance formula used is:
C = U (insulin) x Volume / P (insulin) |
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Decrease filtration coefficient = renal disease, DM, HTN
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For many disease as you lose nephrons you lose glomerular filtration coefficient and lose surface area of the functioning nephrons
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Increase Bowman’s capsule hydrostatic pressure = Urinary tract obstruction (kidney stones)
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Stop making urine completely you will not have any GFR on side with stones
o Urine backs up to the ureters, into the nephrons, distal tubule, loop of henle, and ultimately backs up into Bowman’s capsule until hydrostatic pressure in the capsule is so high that it wont allow any glomerular filtration |
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PERFECTION: Automatic
Main Type Only |
PMSI in CONSUMER GOODS
Note: PMSI in inventory or equipment must be filed. |