Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
26 Cards in this Set
- Front
- Back
What is the target of SMX/TMP?
|
Antimetabolite --> blocks folate synthesis
|
|
Which ABX is likely to cause kernicterus?
|
SMX/TMP
|
|
Which ABX is likely to cause Acute Hemolytic Anemia in a G6PD deficient pt?
|
SMX/TMP and Nitrofurantoin
|
|
Which ABX is likely to cause achilles tendon rupture?
|
FQs
|
|
What is the target of FQs?
|
block DNA gyrase and Topoisomerase IV
|
|
Which ABX form reactive species that damage bacterial DNA?
|
Urinary antiseptics (nitrofurantoin)
|
|
What are the FQs?
|
Ciprofloxacin, Moxifloxacin, Levofloxacin, Norfloxacin
|
|
What are the AGs?
|
Gentamicin, Tobramycin, Amikacin, Neomycin, Streptomycin
|
|
What are the Tetracyclines?
|
Doxycycline, Minocycline, Tigecycline
|
|
What are the Streptogramins?
|
Quinupristin, Dalfopristin
|
|
What are the Macrolides?
|
Erythromycin, Azithromycin, Clarithromycin
|
|
Which ABX is most likely to produce nephrotoxicity?
|
AGs
|
|
Which ABX is associated with Gray Baby syndrome?
|
Chloramphenicol
|
|
What is the target of chloramphenicol?
|
50S blocks peptide bond formation
|
|
Which ABX produce pseudomembranous colitis?
|
Clindamycin and tetracyclines
|
|
Which ABX inhibit MAO?
|
Linezolid
|
|
Which ABX are potent CYP3A4 inhibitors?
|
Streptogramins
|
|
Which ABX chelate with cations, get into bone and stain teeth?
|
Tetracyclines
|
|
Which ABX have a unique resistance mechanism where bac proteins compete with the drug for binding?
|
Tetracyclines
|
|
Which ABX could be used against pseudomonas?
|
AP Pen, 3rd gen AP ceph, imipenem, tobramycin, aztreonam, ciprofloxacin
|
|
Which drugs are effective against E. faecalis and faecium?
|
Linezolid, Daptomycin
|
|
Which ABX are eliminated metabolically?
|
Macrolides, Streptogramins, Linezolid
|
|
Which ABX is likely to cause red man syndrome?
|
Vancomycin
|
|
Which ABX are effective against MRSA?
|
Vancomycin, Streptogramins, Linezolid, Daptomycin
|
|
Which protein synthesis inhibitors are bacteriocidal?
|
AGs, streptogramins (in combo)
|
|
Which ABX would give a pt brown piss?
|
Nitrofurantoin
|