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52 Cards in this Set
- Front
- Back
What acid base imbalance often occurs with renal failure?
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Metabolic Acidosis
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Use phosphoru binding mecications to treat what?
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hyperphosphatemia
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Complications of transplantation (2)
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1. Finding compatible donor
2. Rejection |
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Peritoneal Dialysis
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fill
dwell drain |
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How long does the soln usually dwell in peritoneal dialysis?
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4 to 6 hours
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How often for hemodialysis?
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Every three to five days for 3-5 or more hours at a time.
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Initian Phase in ARF
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1-2 days
reduced urine output and increased BUN |
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Oliguric phase (Maintance) in ARF
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1-2 weeks
hyperkalemia and fluid volume overload |
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Polyguric Phase (Diuretic) in ARF
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progressive increase in urination in pts that were olyguric
May indicate beginning of renal repair Substantial renal loss of sodium and water May dehydrate |
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Phase of Functional recovery
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No beginning or end
Repair of renal injury BUN, creatinine, and urine volume gradually return to normal. |
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5 stages of chronic renal failure
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1. slight damage GFR more than 90
2.Mild decrease in function GFR 60-89 3. Mod decrease in function GFR 30-59 4. Sever dEcrease in function GFR 15-29 5. kidney failure GFR less than 15 |
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What is the main protein found in the urine?
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albumin
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What are the filters of the kidney?
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glomeruli
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Proteinuria is caused by what?
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glomerulonephritis
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Glomererular Filtration is best checked by what lab?
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Blood creatinine
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What lab checks the ability of the kidneys to concentrate urine?
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Urine Specific Gravity
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What is the diet ordered for patient with renal failure?
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Low protein
Low sodium High calorie |
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Antidiuretic Hormone effects kidneys by
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controlling permeability
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Aldosterone effects kidneys by
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causing the distal tubule and collecting ducts to reabsorb increased levels of sodium.
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Causes of intrarenal ARF
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*Glomerulonephritis*
Nephrotoxic damage NSAID's heavy metals |
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Causes of postrenal ARF
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*calculi (kidney stones)*
obstruction of indwelling cath tumors |
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Causes of prerenal ARF
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Sepsis
dehydration hemmorhage heart/liver failure burns |
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How long does recovery phase last?
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About 6 months
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Renin-Angiotensin Mechanism
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one of the most potent vasoconstrictors known.
RAS is a defense mechanism to prevent fall in BP due to loss of blood or fluid. It can be improperly activated in renal disease causing HTN. |
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Alterations in fluid may produce what?
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Generalized Edema
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Accumulation of wastes (amonia) may cause what?
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Mucosal Errosion
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Alterations in platelet function may lead to what?
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Eccymosis
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What is a "silent killer"?
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Hypertension
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Causes of Acute Renal Failure ARF
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1. prerenal- low blood flow to kidneys
2.intrarenal-direct damage to kidney parenchyme 3.postrenal-obstruction to flow of urine(may cause hydronephrosis) |
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What is ARF
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Rapid deterioration or cessation in kidney function.
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ARF and childhood!
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It is uncommon in childhood!!
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Biggest cause of prerenal failure!
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Hemmorrhage
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Biggest cause of post renal failure.
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Renal Calculi
(more men than women have renal calculi) |
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Biggest cause of intrarenal failure.
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glomerulonephritis.
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Children with untreated strep may end up with what?
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pyelonephritis
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Chronic Renal Failure
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Progressive and Irreversible Destruction of kidneys.
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CRF caused by what?
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Conditions that cause permanent nephron loss:
diabetes, HTN, glomerulonephritis, polycystic kidney disease |
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Each kidney contains how many nephrons?
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one million
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Diminished Renal Reserve
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GFR 50% of normal
usually 40-70 mL/min |
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Renal Innsuffiency
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GFR 20-50%
usually 20-40 mL/min |
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Renal Failure
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GFR less than 20%
usually 10-20 mL/min |
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End Stage Renal Disease (ESRD)
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GFR less than 5%
usually less than 10 mL/min Requires dialysis for survival |
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What med is used for hyperkalemia?
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Kayexalate
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Clinical Manifestations of Chronic Renal Failure
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Hyperlkalemia
High or low Na Hyperphosphatemia |
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Peritoneal Dialysis
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Watch for abnormal soln color, should be straw colored.
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Procurement Interview
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Checks for possible donor.
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Avoid using ________with antacids or mg because of toxicity.
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Aluminum Hydroxid
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Epogen given for renal failure.
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To see if it is working, check to see if Hematocrit level is rising.
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Dry scaley skin with ecchymoses, petechiae, and purpura.
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Because of eurythropeotin
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Facts about acute renal failure
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-occurs suddenly
-usually reversible -3 phases oliguric, diuretic, and recovery |
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Emergency tx of hyperkalemia.
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dialysis and 50% hypertonic glucose IV, calcium gluconate IV, regular insulin, sodium bicarb IV, Kayexelate
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Lab results with ARF
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-urine output below 400 mL in 24 hours
-increased blood urea nitrogen level -increased serum creatine - |