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11 Cards in this Set
- Front
- Back
- 3rd side (hint)
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What 3 lab parameters are used to evaluate RBC mass in anemia? |
Hemoglobin, hematocrit, RBC count. These are surrogates for RBC mass. |
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Where is iron absorbed? |
Duodenum |
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Stages of iron deficiency? |
Storage iron is depleted Serum iron is depleted Normocytic anemia Microcytic hypchromic anemia |
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Iron deficiency labs? |
Microcytic hypochromic anemia with increased RDW Decreased ferritin Increased TIBC Decreased serum iron Decreased percent saturation Increased free erythrocyte protoporphyrin (FEP) |
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Treatment of iron deficiency anemia? |
Ferrous sulfate |
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Symptomatic triad of Plummer Vinson syndrome? |
(Iron deficiency) Anemia Dysphagia (due to esophageal web) Beefy red tongue (atrophic glossitis) |
B A D |
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Name these cells |
Ring sideroblast |
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What is thalassemia and what is it due to? |
It is decreased synthesis of globin chains of hemoglobin. It is due to an inherited mutation (which imparts immunity against plasmodium falciparum malaria). |
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What is Hb Barts? |
Tetramer of gamma chains. Lethal in uterine (hydrops fetalis) since they damage RBCs. |
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Causes of macrocytic anemia (besides those causing megaloblastic anemia)? |
Liver disease Alcoholism Drugs e.g 5-FU |
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Proteins involved in hereditary spherocytosis? |
Membrane tethering proteins i.e Spectrin, Ankyrin, Band 3.1 |
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