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32 Cards in this Set

  • Front
  • Back

What is the distance between two bonds between the basis of double helical structure of DNA?

0.34nm


3.4A

What Is the distance between each turn of DNA helix?

3.4nm


34A

What is the distance between both strands of DNA in helical structure?

2nm


20A

What is the meaning of word allele and from which language it comes from?

Greek word allelos


Meaning each other

Who and when isolated DNA from WBCs harvested from first socked bandages?

Miescher


1869

Who and when evidence get DNA is the genetic material, not protein?

Avery


1944

Who and when discovered double helical model for DNA?

Watson and Crick


1953

Who and when discovered DNA polymerase and when he got the Nobel prize?

Korenberg


1956


Nobel prize in 1959

Who and when discovered DNA renaturation, establishing the specificity and feasibility of nucleic acid hybridization reaction?

Marmur and Duty


1961

Who and when evidence the presence of DNA restriction endonuclease?

Werner Arber


1962

Who purified the DNA restriction endonucleases and use in DNA sequence characterization?

Nathans and H. Smith

Who and when elucidated the genetic code?

Nuremberg, Ochoa and Khurana


1966

Who and when discovered DNA ligase?

Gillert


1967

Who and when developed the DNA cloning techniques?

Boyer, Cohn, Berg


1972-73

Who and when developed gell transfer hybridization for the detection of specific DNA sequence?

Southern


1975

Who and when developed rapid DNA sequence methods?

Sanger, Barrell Maxam and Gilbert


1975-77

Who and when produced transgenic mice?

Palmiter and Brinster


1981-82

Who produced transgenic fruit flies?

Spradling and Rubia

Who and when established the NIH's public change sequencing database at Los Almos National Lab?

GenBank


1982

Who and when invented PCR?

Karry Mullis


1983

Who and when introduced methods for targeted gene replacement in mouse embryonic cells?

Capecchi and Smithies


1987

Who and when developed yeast two hybrid system for protein interaction?

Fields and Song


1989

Who and when released BLAST?

Lipman


1990

Who and when automated DNA sequence homology?

Hood and Hankapillar


1991

Who and when sequenced first complete genome of Bac. Haemophillus influenzae?

Venter


1995

Who and when sequenced saccharomyces cereviseae?

Goffeau


1996

Who and when produced DNA microarrays?

Lockhart and co


1996-97

Who and when sequenced nematode?

Sulston and Waterston


1998

Who and when announced the completion of first draft of human genome?

Consortia of research


2001

When the first draft of human genome was completed?

2003

Who and when sequenced chimpanzee?

Consortia of research


2005

Who and when discovered RNAi?

Craig C Mello


2006