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29 Cards in this Set
- Front
- Back
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apraxia
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problems with functional tasks
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aphasia
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language difficulties - remembering words
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agnosia
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inability to recognize people, objects
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average survival years of alz dementia patient
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8 years
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what chromosomes are ass with early onset dementia
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1, 14, 21
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B-amyloid neuritic plaques and hyperphosphorylation of tau proteins to form neurofirillar tangles is associated with what disease
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Dementia
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AD is characterized by a decrease or increase of NTs?
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decrease (drugs target NT replacement)
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The early stage of AD affects instrumental or basic ADLs?
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instrumental
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Should we use antipsychotics in Lewy body dementia?
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Use caution since there is a neuroleptic sensitivity for increased risk of EPS
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Which AChE-Is has a mild to severe AD indication?
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Donepezil
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What are some big side effects to monitor for with AChE-Is?
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bradycardia, weight loss
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Which AChE-Is has a mild to moderate indication for AD?
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Galantamine/rivastigmine
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Which two AChE-Is need to be given with food
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Galantamine/rivastigmine
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Which AChE-Is do you want to avoid with renal/liver failure?
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Glanantamine/rivastigmine
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What is the AD indication for Memantine?
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moderate to severe
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Is menmatine used alone or in combo with a AChE-I?
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in combo
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Is there an FDA approved med for behavior change in dementia?
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none
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Benefits of anti-psychotic agents are likely to be small and offset by AEs. T or F
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True
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Does the use of Buspirone have evidence of efficacy for dementia?
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little evidence
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Trazadone can be used for what behavioral symptoms associated with dementia?
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agitation and aggression if SSRI not effective
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Propranolol can be used for what behavioral symtoms ass with dementia?
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impulsive, hostility, assaultive
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Antipsychotics causing alpha blockage cause what side effect?
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OH
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When should GDRs be initiated?
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1st year: 2 times in a one year period at least a month apart
2nd year: annually (don't if CI though) |
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What are the CIs with GDRs?
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Indication for dementia behavioral symptoms?: symptoms returned or worsened after last GDR and physician has documented rationale
Using for psych disorder: used with guielines + physician documentation or symtpoms worsen after most recent BDR with MD documentation over rationale |
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Starting dose of Donepezil
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5 mg and increase at 4-6 weeks
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Starting dose of Galantamine
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4 mg BID, titrate to 8 mg BID in 4 weeks
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Starting dose of rivastigmine
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1.5 mg BID, titrate in 2 weeks to 3 mg BID (6 mg/day)
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Overall do medications for dementia only slow the progression of the disease?
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Yes
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If a patient with dementia is experiencing hallucinations, what type of dementia do you suspect?
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Lewy Body
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