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69 Cards in this Set

  • Front
  • Back
(centre)

(centre)

acanthocyte

anisocytosis

2nd row, 2nd from left

2nd row, 2nd from left

bar cell


which WBC?

which WBC?

basophil

Which WBC?

Which WBC?

basophil

basophilic stippling


dacryocyte

echinocytes or poikliocytosis

elliptocytes

which WBC

which WBC

eosinophil

eosinophil

neutrophil

fusocyte

(with protrusions)

(with protrusions)

Heinz bodies

with dots

with dots

Howell-Jolly bodies

(5 o'clock)

(5 o'clock)

keratocyte

leptocyte

lymphocyte

lymphocyte

lymphocyte

lymphocyte

monocyte

monocyte

neutrophil

poikilocytosis

poikilocytosis

rouleaux

schistocytes

spherocyte

stomatocyte

stacked like poker chips


common in healthy horses


less common in cats, dogs


rare in ruminants


increase in inflammatory disease (increased fibrinogen or globulin concentration)

rouleaux formation

unorganized 3D clustering


serious issue


immune system disorder


antibody coats the RBC

agglutination

agglutination vs rouleaux formation?

rouleaux is more linear, can tell cells apart somewhat

difference in cell size, rated as low, moderate or marked

anisocytosis

with a high MCV you will often see

macrocytes

with a low MCV you will often see

microcytes


usually juvenile polychromatic erythrocytes (reticulocytes)


may indicate regenerative response

macroctyes

usually deficient in essential nutrients such as iron

microcytes

cells that stain lighter than the surrounding RBCs due to lower Hb

hypochromic

what test would confirm hypochromasia

mean corpuscular Hb concentration (MCHC)

when cells stain darker

hyperchromic

RBCs with faint blue colouring due to organelles left in cytoplasm


usually macrocytic and immature

polychromasia


what would an abundance of reticulocytes indicate

an increase in bone marrow production

normal staining intensity

normochromasia

normal shaped RBC

discocyte

presence of abnormally-shaped RBCs, general term

poikilocytosis


crenated RBCs


blunt, short, evenly-spaced projections around edge


often most common altered RBC found

echinocyte


associated with renal disease, lymphosarcoma in dogs, exercise in horses, after rattlesnake bite venom poisoning

echinocyte

resemble echinocytes


projections are irregularly spaced, club like, varying length and diameter


acanthocytes


occur in cats with hepatic lipidosis, dogs with liver disease esp. hemangiosarcoma of liver, and kidney disease

acanthocytes

flattened RBCs with large surface area, decreased cell volume


may fold or become distorted or wrinkled


may fold over into bowl shapes

leptocytes

central staining area that resembled bull's eye


may be found in animals with liver disease or reticulocytosis

codocyte

similar to codocyte except has dark bar in centre extending to both sides


common with chronic disease esp. nonregenerative anemia


bar cell (knizocyte)

elongated curved central pallor that resembles a mouth


common with chronic disease esp. nonregenerative anemia

stomatocyte

thick, spherical, darkly-staining cells


smaller than normal RBCs


no central pallor


decreased surface area


suggests immune-mediate hemolytic anemia (IMHA)or mismatched blood transfusion

spherocyte


oval or cigar shaped


found in various anemias


large amounts in hereditary elliptocytosis

elliptocyte

RBC fragments due to intravascular trauma (fibrin strands)


may indicate serious illness


disseminated intravascular coagulopathy , vascular neoplasms and iron deficiency

schistocytes


speculated with 2 or more points


forms blister/vacuole, enlarges and opens


iron-deficiency anemia allows for oxidative injury to cell

keratocyte

teardrop shaped

dacryocyte


pointed at each end, similar to a lemon

fusocyte


small to medium dark blue dots inside an RBC

basophilic stippling

commonly seen in immature RBCs of ruminants, regenerative response of the bone marrow (anemia) and lead poisoning

basophilic stippling

small round portion of basophilic remnants of the nucleus retained in cell


seen in patients after splenectomy or with spleen disorder (spleen usually removes nuclear remnants)

Howell-Jolly bodies

early release of immature RBCs with anemia and lead poisoning, except in birds and reptiles

nucleated RBCs

common in cat RBCs


found in lymphosarcoma cases, hyperthyroidism and diabetes mellitus in cats

Heinz bodies


Granulocytes?

Neutrophil


Eosinophil


Basophil

Agranulocytes

Lymphocyte


Monocyte

main differences between lymphocyte and monocyte?

lymphocyte has large nucleus, monocyte has vacuoles


difference between the granulocytes?

neutrophils have very twisted nucleus with light purple cytoplasm, looks grainy but no granules


basophils have larger nucleus with visible purple granules (purple-blue)


eosinophils have orange and blue granules