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Why does this ish make a **** wanna JUMP JUMP.???... When a patient has an ENLARGED (but NON-tender) gallbladder and mild jaundice (courvosier's sign)? Less likely to be a gallstone.. Why? What other pathology could cause a backup of fluid like th...

Why does this ish make a **** wanna JUMP JUMP.???... When a patient has an ENLARGED (but NON-tender) gallbladder and mild jaundice (courvosier's sign)? Less likely to be a gallstone.. Why? What other pathology could cause a backup of fluid like this??

weight loss, painless jaundice, and enlarged gallbladder... Watch out for pancreatic cancer!!

weight loss, painless jaundice, and enlarged gallbladder... Watch out for pancreatic cancer!!

gallstones are formed over an extended period of time, resulting in a shrunken, fibrotic gall bladder which does not distend easily. This shrunken gallbladder is less likely to be palpable on exam. In contrast, the gallbladder is more often enlarged (and more easily palpated) in pathologies that cause obstruction of the biliary tree over a shorter period of time such aspancreatic malignancy leading to passive distention from back pressure



risk factors: male,

You see someone with Super fast tachycardia, hallucinations, dilated pupils and think they may have some toxic overdose. What is a key difference between someone with ANTI-CHOLINERGIC syndrome versus someone that has a  caffeine overdose (sympa...

You see someone with Super fast tachycardia, hallucinations, dilated pupils and think they may have some toxic overdose. What is a key difference between someone with ANTI-CHOLINERGIC syndrome versus someone that has a caffeine overdose (sympathomimetic)?


i.e. whats the difference between a less parasympathetic (anti-ach) versus overactive sympathetic?

Anticholinergic (hot as a hare, dry as a bone, red as a beet, mad as a hatter)
 
a sympathomimetic = MOIST SKIN AND HYPERACTIVE BOWEL SOUNDS
think coffee (or molly, youre sweating)

Anticholinergic (hot as a hare, dry as a bone, red as a beet, mad as a hatter)



a sympathomimetic = MOIST SKIN AND HYPERACTIVE BOWEL SOUNDS


think coffee (or molly, youre sweating)


What should you give to a child that had one to many DELICIOUS flintstones vitamins? After enjoying how yummy they were, his tummy started really hurting...having bloody throw-up but then was okay. Then he started having hypovolemic shock (iron is...

What should you give to a child that had one to many DELICIOUS flintstones vitamins? After enjoying how yummy they were, his tummy started really hurting...having bloody throw-up but then was okay. Then he started having hypovolemic shock (iron is a potent vasodialator). How do we clean out the iron from the blood?

deFEROXamine= iron chelating agent (de-ferrous/ in the blood)


Out of the multiple endocrine neoplasias, why might you see hypercalcemia complications (kidney stones, lethargy) in someone with  MEN1 and MEN2A, but not see in MEN2B? 
Out of the multiple endocrine neoplasias, why might you see hypercalcemia complications (kidney stones, lethargy) in someone with MEN1 and MEN2A, but not see in MEN2B?
PARAthyroid neoplasia!! = 1 & 2A which means you would see HYPERCALCEMIA, and more kidney stones


MEN2B = MARFAN like syndrome

PARAthyroid neoplasia!! = 1 & 2A which means you would see HYPERCALCEMIA, and more kidney stones





MEN2B = MARFAN like syndrome
lab findings with PRIMARY HYPERPARATHYROIDISIM=

high:


serum PTH


serum Calcium


serum alkaline phosphatase


urinary cAMP




decrease:


serum phosphate






Complications include nephrolithiasis, nephrocalcinosis, CNS disturbances (depression/seizures), constipation, peptidic ulcer disease, acute pancreatitis, OSTEITIS fibrosa cycstica

This patient is getting a PPD test... but you notice something funny... His 30 year old tattoos have flared up recently. What condition might this patient have that might make a PPD test not work?
This patient is getting a PPD test... but you notice something funny... His 30 year old tattoos have flared up recently. What condition might this patient have that might make a PPD test not work?
Bubbly rxn to old tattoo= SARCOIDOSIS disease activation
commonly ANERGIC so would need a positive test control if you are doing a PPD test for TB.

No infectcious agent, nothing in the middle of granuloma

SCars & tattoos have disease activation....

Bubbly rxn to old tattoo= SARCOIDOSIS disease activation


commonly ANERGIC so would need a positive test control if you are doing a PPD test for TB.




No infectcious agent, nothing in the middle of granuloma




SCars & tattoos have disease activation. Hallmark of sarcoidosis.




Erthyma nodosum= painful red brown nodules


If you see this and papules on the skin, what is it until proven otherwise? What can you give them to help them with the papules?
If you see this and papules on the skin, what is it until proven otherwise? What can you give them to help them with the papules?
SARCOIDOSIS UNTIL PROVEN OTHERWISE!!
SARCOIDOSIS UNTIL PROVEN OTHERWISE!!

For GRANULATOMOUS inflammation, like in sarcoidosis, One o the key mediators of this rxn is TNF- alpha. Which would be a great drug to use?? (how might it be bad for someone that has TB though?)
For GRANULATOMOUS inflammation, like in sarcoidosis, One o the key mediators of this rxn is TNF- alpha. Which would be a great drug to use?? (how might it be bad for someone that has TB though?)
INFLIXIMAB- TNF-alpha inhibitor="GRANULOMA BUSTING"

careful about opening up granulomas though! We see TB flareups/ histosis in lungs that old granulomas walled off. uh oh

doesn't make you more susceptible, but will cause inactive disease to bec...

INFLIXIMAB- TNF-alpha inhibitor=
"GRANULOMA BUSTING"




careful about opening up granulomas though! We see TB flareups/ histosis in lungs that old granulomas walled off. uh oh




doesn't make you more susceptible, but will cause inactive disease to become active again


What is the difference  between PEMPHIGUS vulgaris (looks like SJS) vs. bullous pemphiGOID (old people, blistering, itching) ?? Which one has Ig against desmoglien-3 (Cells to cell adhesion ) and which one is  hemidesmosomes (basal cells to ...
What is the difference between PEMPHIGUS vulgaris (looks like SJS) vs. bullous pemphiGOID (old people, blistering, itching) ?? Which one has Ig against desmoglien-3 (Cells to cell adhesion ) and which one is hemidesmosomes (basal cells to basement membrane)?
pemphigus vulgaris= desmoglien 3
"net like"

bullous pemphigoid=hemidesmosomes

pemphigus vulgaris= desmoglien 3


"net like"




bullous pemphigoid=hemidesmosomes


You poke someone with psoriasis and this happens... What is this called?
You poke someone with psoriasis and this happens... What is this called?
Kobner phenomenon. This can also happen too
Kobner phenomenon. This can also happen too

For really gnarly psorisasis... (which can happen when you give steroids and then stop suddenly...) What is the best treatment for this condition?
For really gnarly psorisasis... (which can happen when you give steroids and then stop suddenly...) What is the best treatment for this condition?
ACITRETIN, BUT it is teratogenic, so obvi don't give to preggers person
ACITRETIN, BUT it is teratogenic, so obvi don't give to preggers person

Just loose association... Which drugs here would be best used for certain diseases...?
Just loose association... Which drugs here would be best used for certain diseases...?