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51 Cards in this Set
- Front
- Back
what are the five layers of keratinocytes in the epidermis from deep to superficial
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stratum- basale, spinosum, granulum, lucidum, corneum
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in what layer of the epidermis do keratinocytes turn into keratinized squames
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stratum lucidum
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in what layer of the epidermis would you find lamellar bodies (lipid and hydrolytic enzymes)
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stratum granulosum
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from what amino acid is melanin made from
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tyrosine (enzyme: tyrosinase)
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which type of albinism exists when there is no tyrosinase enzyme
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Type I albinism
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what type of albinism exists when there is no transmembrane trasnporter protein to get stuff to mealnosomes
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Type II albinism
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what type of albinism occurs when there isn't any myosin to move melonosomes
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Type I Griscelli Syndrome
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what cell in the epidermis functions as an antigen presenting dendritic cell, and will migrate to lymph nodes
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langerhans cells
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what cells in the epidermis are mechanoreceptors in the stratum basale
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merkel cells
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in what layer of the epidermis would you expect to find langerhans cells
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stratum spinosum
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in what layer of the epidermis would you expect to find melanocytes
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stratum basale with processes into stratum spinosum
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what is the name of the structure that projects from the dermis into the epidermis
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dermal papillae
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what is the name of the epidermis that surround the dermal papillae
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rete ridges
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what are the two layers of the dermis from superficial to deep
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papillary layer and reticular layers
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the reticular layer of the dermis is made of
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dense irregular CT
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where would you find meissner's corpuscles
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dermal papillae
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what three things would you find in a dermal papillae
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capillary loop, lymphatic capillary, and meissner's corpuscle
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the hair shaft and inner root sheath develop from what portion of the hair follicle
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hair bulb
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what structure induces development of the hair bulb
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dermal papillae
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the inner root sheath of hair does not extend to the surface of skin, but breaks off at this structure
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infundibulum
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what term describes active hair growth where the hair bulb has moved deep
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anagen
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what term describes regression of hair and the hair bulb moves to the skin
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catagen
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what term describes a resting, non growing hair follicle
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telogen
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what type of gland has alveolar glands, secrete lipids, and pheromones via holocrine secretion and are regulated by sex hormones
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sebaceous gland
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normally what type of gland is a sweat gland
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simple unbranched coiled tubular gland
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what type of sweat gland is not associated with a hair follicle and involved in thermoregulation and can resorb NaCl
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Eccrine sweat gland
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what type of of sweat gland is associated with hair folicle in axilla, anogenital and areolae of breasts
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apocrine sweat glands
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which are larger, apocrine or eccrine sweat glands
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apocrine
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in mammary glands the proteins are secreted by ___ mechanism and lipids are secreted by ___ mechanism
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merocrine/apocrine
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in what layer of the epidermis would you find proliferating keratinocytes and immature post-mitotic cells
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stratum basale
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in what layer of the epidermis would you find cells focused on production of proteins and other stuff for keratinization
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stratum spinosum
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in what layer of the epidermis would you find cells filled with bundles of keratin filaments
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stratum spinosum
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the stratum granulosum contains keratohyalin granules that are aggregates of ...
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proflaggrin (not within membrane)
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in the stratum spinocum ___ are present and contain lipid and hydrolytic enzymes that will be important in forming a water impermeable layer
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lamellar granules
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changes in the rate of production or loss of squmes will result in a disease known as...
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ichthyoses
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what shape is the melanocyte nucleus
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ovoid
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langerhans cells can be differentiated from keratinocytes due to their lighter staining cytoplams, deeply indented nucleus and ___ shped endosomes
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tennis-racket
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what is the name of the granule in langerhans cells that are involved in the acquisition and storage of antigen
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Birbeck granules
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in what parts of the body would you expect to find greater numbers of merkel cells
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areas of enhanced tactile perception
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where would you most likely find epidermal rete ridges and dermal papillae
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glabrous skin (non hairy)
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where are the two main plexuses of vessels in the dermis
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superfical plexus at papillary/reticular junction and deep plexus at cutaneous/subcutaneous junction
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the hair follicle, sebaceous glands, apocrine sweat glands, and arrector pili are all part of the...
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philosebaceous unit
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what are the borders of the infundibulum of the hiar follicle
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from skin to sebaceous glands
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what are the borders of the isthmus of the hair follicle
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sebaceous gland to arrector pili muscle
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what are the borders of the inferior portion of the hair follicle
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anything deep to the arrector pilli muscle
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which of the sweat glands actively resorbs NaCl
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eccrine sweat gland
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which sweat gland will collect the fluid in the duct prior to secretion
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apocrine sweat gland
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the main duct or lactiferous duct is lined by...
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stratified squamous epithelium
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just deep to the lactiferous duct there is an expansion known as...
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lactiferous sinus
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the larger ducts, or ducts draining into the lactiferous sinus are lined by
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stratified cuboidal epithelium
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smaller ducts which feed into larger ducts are lined by...
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simple cuboidal/columnar
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