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8 Cards in this Set
- Front
- Back
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what are the features of purines?
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Nitrogen-ring,P-P-P (atp, adp,..)
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in which functions are purines involved?
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housekeeping, signaling cell damage, mediating sensory signal transduction.
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what are the kind of receptors purines work on?
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g-protein coupled (P2X1-7), ionchannel (P1A,2Y)
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how does the housekeeping function work?
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the ATP is coupled with the neurotransmitter. activating the reuptake of neurotransmitter
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how does cell damage signaling work?
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when a cell breaksdown ATP leaks and activates painreceptors
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in which sensory signal transduction cascades are purines involved?
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bladder streach, respiration (pCO2,O2), taste,
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how do purines affect sleep?
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during the day ATP,DP,MP levels drop, thereby shutting down the 'attention' neurons (ACh) in the cortex when only adenosine is left
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where does caffeine work in the attention system?
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it blocks the adenosine (A1) receptor, which is supressing alertness
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