Psychopharm Lecture 3.5

Front 1

Brand Name for Venlafaxine?

Back 1

Effexor

Front 2

Venlafaxine: FDA approved for what 4 things?

Back 2

MDD, GAD, panic dx, SAD

Front 3

Off-label use of Venlafaxine for what? (4)?

Back 3

pain in fibromyalgia, neuropathy, PTSD, and premenstrual dysphoric dx

Front 4

____ antidepressants are freuqently the antidepressants of choice in depressed patients with neuropathic pain

Back 4

SNRIs

Front 5

Brand names of Desvenlafaxine? (2)

Back 5

Pristiq; Khedezla

Front 6

Desvenlafaxine FDA approved for what? (1)

Back 6

MDD

Front 7

Off-label use of Desvenlafaxine (2)?

Back 7

Anxiety disorders and neuropathic pain in diabetes/fibromyalgia

Front 8

Duloxetine: brand name? (1)

Back 8

Cymbalta

Front 9

Duloxetine FDA approved for what? (4)

Back 9

MDD, Anxiety dx, management of diabetic pain, fibromyalgia,

Front 10

Off-label use of duloxetine (5)

Back 10

Pain conditions, panic dx, PTSD, social phobia, stress incontinence

Front 11

Levomilnacipran: brand name (1)?

Back 11

Fetzima

Front 12

Levomilnacipran FDA approved for what? (1)

Back 12

MDD

Front 13

Off-label use of Levomilnacipran (2)?

Back 13

Anxiety dxs, and for pain

Front 14

2 types of atypical agents?

Back 14

Bupropion, Mirtazapine

Front 15

Buproprion mechanism is ___ understood. Atypical agents work on ___ and ____.

Back 15

not; norepinephrine, dopamine

Front 16

Brand name for Bupropion? (5)

Back 16

Wellbutrin SR, Wellbutrin XL, Zyban, Aplenzin, Forfivo XL

Front 17

Bupropion FDA indicated for what 2 things?

Back 17

MDD and smoking cessation

Front 18

Off-label use of Bupropion for what 3 things?

Back 18

ADHD, neuropathy, and premenstrual dysphoric disorder

Front 19

Bupripion has no side effects for what 2 things?

Back 19

sexual side effects, and appetite

Front 20

2 precautions for bupropion?

Back 20

Seizures and weight loss.

Front 21

Buproprion can reduce ___ threshold

Back 21

seizure

Front 22

Mirtazapine is a ___ antidepressant

Back 22

tetracyclic

Front 23

Mirtazapine increases neurotransmission of what 2 things?

Back 23

serotonin and norepinephrine

Front 24

Mirtazapine works by antagozing what 2 receptors?

Back 24

serotonin, alpha 2

Front 25

Brand name for Mirtazapine?

Back 25

Remeron

Front 26

Mirtazapine is FDA indicated for what?

Back 26

MDD

Front 27

Mirtazapine off-label use? (3)

Back 27

Anxiety dxs, nausea, insomnia

Front 28

2 precautions for mirtazapine?

Back 28

orthostatic hypotension, serotonin syndrome

Front 29

Mirtazapine is ___ recommended for women during pregnancy

Back 29

not

Front 30

mirtazapine; drugs that may block the metabolism? (4)

Back 30

antifungals, paroxetine, fluvoxamine, medications for treatment of HIV

Front 31

3 types of serotonin modulators?

Back 31

trazadone; vilazodone; vortioxetine

Front 32

trazadone is what 2 things?

Back 32

serotonin antagonist; serotonin reuptake inhibition

Front 33

trazodone also blocks ___ receptors, leading to ___

Back 33

histamine; sedation

Front 34

Brand name of trazodone?

Back 34

None

Front 35

Trazadone is FDA indicated for what?

Back 35

MDD

Front 36

Off-label use of trazodone (2)?

Back 36

aggression in intellectual disablity, and dementia

Front 37

Trazodone: rare side effects?

Back 37

visual disturbances - seeing visual trails

Front 38

unique precaution of trazodone?

Back 38

priapism - uncontrolled persistent erection

Front 39

Is Trazodone recommended for pregnancy?

Back 39

No

Front 40

____ has effects on SSRI as well as stimulation of serotonin receptors by partial agonism

Back 40

Vilazodone

Front 41

Vilazodone brand name?

Back 41

Viibyrd

Front 42

Vilazodone is FDA indicated for what?

Back 42

MDD

Front 43

Off-label use of Vilazodone for what?

Back 43

anxiety

Front 44

Vortioxetine: works by ___ serotonin reuptake, also has ___ activities at some receptors and ___ activtiesiat other receptors

Back 44

inhibiting; agonistic, antagonistic

Front 45

Brand name of Vortioxetine (2)?

Back 45

Brintellix; Trintellix

Front 46

FDA approved for Vortioxetine?

Back 46

MDD

Front 47

Off-label use for Vortioxetine?

Back 47

Anxiety