Psych Pharmacology For Shelf Exam

Front 1

Side Effects of TCAs

Back 1

Anihistaminergic: Sedation
Antiadreneric: Orthostatic hypotension and arrhythmias
Antimuscarinic: Dry mouth, constipation, urine retention
LETHAL IN OVERDOSE, CARDIOTOXIC

Front 2

Side Effects of MAOIs

Back 2

Same side effects as TCA because they increase the amount of transmitters in the synapse.
Avoid combo with SSRI (serotonin syndrome) or tyramine rich foods/sympathomimetics (hypertensive crisis)

Front 3

Side effects of SSRIs

Back 3

Sexual dysfunction
Weight loss
Insomnia
Headache
Gi disturbance

Front 4

Side effects of SNRIs

Back 4

Same as SSRI except also increases BP

Front 5

Side effects of Wellbutrin

Back 5

No sexual side effects
Psychosis
Seizure risk
Weight loss
Stimulating

Front 6

Side effects of SARIs (Nefazodone/Trazodone)

Back 6

Sedation
Priapism

Front 7

Side effects of NASA (Mirtazepine)

Back 7

Weight gain
sedation
tremor
agranulocytosis

Front 8

Low Potency Traditional Antipsychotics

Back 8

Chlorpromazine
Thioridazine

Have increased risk for sedation but decreased risk for EPS/NMS

Front 9

High Potency Traditional Antipsychotic

Back 9

Haloperidol
FLuphenazine
Trifluoperazine
Perphenazine
Pimozide

Increased risk of EPS/NMS but decreased risk of sedation

Very good at treating positive symptoms

Front 10

Antidopaminergic effects of Traditional Antipsychotics

Back 10

Parkinsonism- cogwheel, pill rolling tremor
Akathisia- anxiety and restlessness
Dystonia- Sustained muscle contractions

Front 11

Treatment of EPS

Back 11

Amantadine
Benadryl
Benztropine

Front 12

Eye problems with Traditional Antipsychotics

Back 12

Thioridazine- irreversible retinal pigmentation
Chlorpromazine- deposits in lens and cornea

Front 13

NMS

Back 13

Occurs most often after beginning AP
Fever
Autonomic instability
Leukocytosis
Tremor
Elevated CPK
Rigidity

Front 14

Treatment for NMS

Back 14

Sodium Dantrolene
Bromocriptine
Amantadine

Also give supportive care ie cooling blanket, hydration

Front 15

Atypical Antipsychotics

Back 15

Clazapine
Risperidone
Quetiapine
Olanzapine
Ziprasidone

More effective in treating negative sx of schizophrenia

Front 16

Side Effects of Atypical Antipsychotics

Back 16

Olanzapine- Hyperlipidemia, Diabetes, Weight gain and liver toxicity (LFTs)
Quetiapine- Cataracts (slit lamp exam)
Clozapine- Agranulocytosis

Front 17

Mood Stabilizers

Back 17

Lithium
Carbamazepine
Valproic acid

Front 18

Lithium

Back 18

TOC for acute mania and for prophylaxis in bipolar disorder.
Secreted by kidney and has narrow therapeutic index (0.7-1.2)
Can cause hypothyroidism and nephrogenic DI

Front 19

Factors affecting Lithium levels

Back 19

NSAIDS lower levels
Dehydration, Salt deprivation and kidney damage increase levels

Front 20

Carbamazepine

Back 20

Especially good for mixed episodes and rapid cycling bipolar
SE of hyponatremia, leukopenia, aplastic anemia, agranulocytosis
Teratogenic (NTDs) during pregnancy

Front 21

Valproic Acid

Back 21

Used for treating mixed manic episodes and rapid cycling bipolar.
Causes thrombocytopenia and hepatotoxicity (Get CBC, LFT)

Front 22

Long Acting Benzos
1-3 days

Back 22

Chlordiazepoxide
Diazepam (Valium)
Flurazepam

Front 23

Intermediate Benzos
10-20 hrs

Back 23

Alprazolam (Xanax)- panic
Clonazepam (Klonopin)- panic, anxiety
Lorazepam (Ativan)- panic, alcohol WD
Temazepam (Restoril)- insomnia

Front 24

Zolpidem/Zaleplon

Back 24

Short term treatment of insomnia
Bind to Benzo-binding site
No tolerance/dependence

Front 25

Buspirone

Back 25

Alternative to Benzo or Venlafaxine for treating GAD.
Slower onset than benzos and does not potentiate the CNS depression of alcohol (can use in alcoholic).