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8 Cards in this Set

  • Front
  • Back

Advanced Maternal Age (AMA)

35 years or older at estimated delivery date

Advanced Paternal Age (APA)

40 years or older at conception

Standard Carrier Testing

Positive family history

Population based carrier screening

Based on ethnic background

Universal Carrier Screening

Any individual with no history or increased risk

Standard of care

1st or 2nd trimester screening



CF and SMA screening to any pregnant woman



Tay Sach's, Canavan's, hemoglobinopathy based on ethnicity



Invasive diagnostic testing to high risk patients



Diagnostic testing available to all women

Screening VS Diagnostic

Screening likelihood



Diagnostic determine

Combined Screening

1st and 2nd trimester screening



Integrated: wait for all data at end 2nd semester



Stepwise sequential: inform with 1st trimester data if high risk >1/50