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25 Cards in this Set

  • Front
  • Back
The membrane potential at which there is no net flux of an ion across the membrane is called that ion's ________.
equilibrium potential
The presence of the ________ prevents the dissipation of the concentration gradient for Na+.
Na+/K+ pump
Why is the electrical potential of a membrane at rest closest to potassium's equilibrium potential than to sodium's equilibrium potential?
more potassium channels are open, allowing more potassium to move out of the cell
As a membrane's permeability to a particular ion increases, membrane potential will move ________ that ion's ________.
closer to : equilibrium potential
True/False: The membrane potential of a cell is determined exclusively by that cell's sodium and potassium permeability.
FALSE
True/False: The Nernst equation is used to calculate the resting membrane potential.
FALSE
Whether a membrane is depolarized to threshold or above, the amplitude of the resulting action potential is the same; in other words, once threshold is reached, the action potential will take place. This concept is known as __________.
the "all-or-none principle"
A change in a cell's membrane potential, such that it becomes more positive, is referred to as a ________.
depolarization
The depolarization phase of the action potential is generated by a rapid ________.
opening of sodium channels
The repolarization phase of action potentials in neurons is due primarily to ________.
potassium flow out of the cell
During which of the following states are the majority of voltage-gated sodium channels closed and incapable of opening?
during the absolute refractory period
The all-or-none principle, associated with the action potential, states that ________.
once membrane potential reaches threshold, an action potential will be generated and that action potential will always be the same magnitude
In order for a neuron to move from the absolute to the relative refractory period, a majority of that neuron's sodium channels must have their ________.
inactivation gates open
In myelinated nerve fibers, where do action potentials occur?
nodes of Ranvier
True/False: The magnitude of the action potential is dependent upon the extent to which the change in membrane potential is above threshold
FALSE
Where in the neuron is an action potential initially generated?
axon hillock
The depolarization phase of an action potential results from the opening of which channels?
voltage-gated Na+ channels
The repolarization phase of an action potential results from __________.
the opening of voltage-gated K+ channels
Hyperpolarization results from __________.
slow closing of voltage-gated Na+ channels
What is the magnitude (amplitude) of an action potential?
100 mV
The membranes of neurons at rest are very permeable to _____ but only slightly permeable to _____.
K+; Na+
During depolarization, which gradient(s) move(s) Na+ into the cell?
both electrical and chemical gradients
What is the value for the resting membrane potential for most neurons?
(-70 mV)
The Na+–K+ pump actively transports both sodium and potassium ions across the membrane to compensate for their constant leakage. In which direction is each ion pumped?
K+ is pumped out of the cell and Na+ is pumped into the cell
The concentrations of which two ions are highest outside the cell.
Na+ and Cl-