Pp4 Final (Last Set Of Drugs)

Front 1

Which type of diabetes is juvenile (i.e. absolute insulin deficiency)

Back 1

Type 1

Front 2

What is another name for type 2 diabetes?

Back 2

Relative diabetes

Front 3

Answer choices: Hyper or Hypo glycemia

AE: dizziness, confusion, sweating, irritability, anxiety, nervous, lack of focus, weakness

Back 3

Hypo

Front 4

Which of the following is NOT a symptom of Hyper-glycemia?

nocturia, HA, thirst, confusion, blurred vision

Back 4

confusion

Front 5

If you have a pt who is fasting, what is their blood glucose parameter?

Back 5

70-130 mg/dL

Front 6

What is an ideal A1c for a fasting pt?

Back 6

<7%

Front 7

Insulin secretagogues means what?

Back 7

to help pancrease make more insulin

Front 8

Sulfonylurea agents are drugs that help the pancrease make more insulin

all the time or as glucose concentrations increase

Back 8

All the time

Front 9

What type of agents help the pancrease make more insulin as glucose concentrations increase?

Back 9

Meglitinide agents

Front 10

What type of agent is metformin?

Back 10

Biguanide

Front 11

What type of agents work on insulin resistance w/ musculoskeletal cells?

Back 11

thiazolidinedione agents

Front 12

What type of agents work to slow down glucose absorption after a meal?

Back 12

Alpha-glucosidase inhibitors

Front 13

Glitazones, avandia, and actos can all lead to what?

Back 13

Edema (so be careful w/ CHF)

Front 14

If you have a pt on a sulfonylurea or meglitinide agent, which type of diabetes is contraindicated? (type 1 or 2)

Back 14

Type 1

Front 15

What class of drugs may mask hypoglycemic warnings?

Back 15

BB

Front 16

What is a major class AE of sulfonylurea and meglitinide agents?

Back 16

HypOglycemia

Front 17

Matching time!

Regular glipizide

Regular glyburide

Meglitinides

Amaryl

Glucotrol XL
(match with: pre-meal, w/ meals, before or w/ a meal)

Back 17

Regular glipizide - pre meal

Meglitinides- pre meal

Amaryl - w/ meals

Glucotrol XL- w/ meals

Regular glyburide- before or w/ a meal

Front 18

Amaryl is?

Back 18

Glimepiride

Front 19

Glucotrol XL is?

Back 19

glipizide XL

Front 20

What is glyburide's name brand?

Back 20

Micronase

Front 21

Which of these should you take with your first main meal??

Glucotrol, Amaryl, or Micronase

Back 21

Amaryl (glimepiride)

Front 22

Which of these should you take (30 min) before a meal?

Glucotrol, Amaryl, or Micronase

Back 22

Glucotrol

Front 23

If a pt has renal/hepatic dysfunction, which of these drugs should you take precaution w/?

Glucotrol XL, Amaryl, Micronase

Back 23

Micronase

Front 24

Which of these should a pt take 30 minutes before food or with food?

Glucotrol XL, Amaryl, Micronase

Back 24

Micronase

Front 25

Who's dosage is this: 1-4 mg d

Glucotrol XL, Amaryl, Micronase

Back 25

Amaryl

Front 26

Who's dosage is this: 2.5-20 mg d

Glucotrol XL, Amaryl, Micronase

Back 26

Glucotrol XL

Front 27

Who's dosage is this: 2.5- 40 mg d on an empty stomach

Glipizide, Glimepiride, Glyburide

Back 27

Glipizide

Front 28

What is the dosing of Glyburide?

Back 28

1.25- 20 mg d

Front 29

Which of these works via the sulfonylurea receptor?

Glucotrol, Glipizide XL, Amaryl, Glyburide

Back 29

Amaryl (Glimepiride)

Front 30

If I say "If you don't eat, don't take the medication" which type of agent am I talking about?

Back 30

Meglitinide agents

Front 31

Meglitinide agents are indicated for what type of diabetes?

Back 31

2

Front 32

Name the two meglitinide agents (generic)

Back 32

repaglinide and nateglitinide

Front 33

What is repaglinide's name brand?

Back 33

Prandin

Front 34

What is nateglitinide's name brand?

Back 34

Starlix

Front 35

What is the dosing of Starlix?

Back 35

60-120 mg tid ac

Front 36

What is the dosing of Prandin?

Back 36

0.5-4 mg tid ac

Front 37

If I am counseling and say "You should take this 15 minutes before the meal, but you can take this immediately pre-meal" am I talking about repaglinide or nateglitinide?

Back 37

Prandin (repaglinide)

Front 38

T or F. If a pt doesn't eat lunch, they should skip their dose of Starlix.

Back 38

True

Front 39

T or F, if a pt doesn't eat dinner, they should skip their dose of Prandin.

Back 39

true

Front 40

What is sitagliptin's name brand?

Back 40

Januvia

Front 41

What exenatide's name brand?

Back 41

Byetta

Front 42

What is Glucophage's generic?

Back 42

Metformin

Front 43

What is Glucovance's generic?

Back 43

glyburide/metformin

Front 44

What is acarbose's name brand?

Back 44

Precose

Front 45

Which of these drugs works by mimicking incretin action (GLP-1 agonist), and increases glucose dependent insulin release?

Sitagliptin, Glucovance, Byetta, or Precose

Back 45

Byetta

Front 46

Which of these drugs works by DPP-IV inhibition (i.e. lowers glucose secretion) ?

Sitagliptin, Glucovance, Byetta, or Precose?

Back 46

Sitagliptin

Front 47

Which of these drugs works by acting as an alpha-flucosidase inhibitor?

Sitagliptin, Glucovance, Byetta, or Precose

Back 47

Precose

Front 48

What is the dosing regimine of sitagliptin?

Back 48

100 mg d

Front 49

Byetta is given IM or SubQ?

Back 49

SubQ

Front 50

What is the strength of exenatide?

Back 50

5-10 mcg BID

Front 51

Who's dosing is: 500-1000 mg Bid

Glucophage, Glucophage XL, Glucovance, or Precose

Back 51

Glucophage

Front 52

Who's dosing is: 500-2000 mg q pm (w/ evening meal)

Glucophage, Metformin XL, Acarbose, Precose, or Exenatide

Back 52

Metformin XL

Front 53

What is the dosing of Precose?

Back 53

50-100 mg TID w/ a meal.

Front 54

Do you take Glucovance with our without meals?

Back 54

WITH

Front 55

Which of these drugs requires a dosage adjustment if a pt has a decreased renal function (CrCL<50ml/min)?

Byetta, Glucophage, Glucovance, Januvia

Back 55

Januvia

Front 56

Give me the AE effect most associated w/ sitagliptin.

Back 56

HA

Front 57

If you have a pt using exenatide, you want to counsel them to administer their medication when?

Back 57

before a meal, but within 60 min of the meal.

Front 58

Which of these drugs should you store in the fridge?

Sitagliptin, Acarbose, Exenatide, or metformin

Back 58

Exenatide

Front 59

An AE of ______ (that should last ____) will be seen with Byetta.

Back 59

Nausea and lasts the first 3 weeks

Front 60

Which of these drugs should you titrate slowly?

Sitagliptin, Exenatide, Glucophage, Precose

Back 60

Glucophage

Front 61

What is the major AE of metformin use?

Back 61

GI issues (like diarrhea, Nv)

Front 62

How is metformin eliminated?

Back 62

90% unchanged in the urine (renally)

Front 63

T or F. You should take metformin WITH meals and avoid alcohol.

Back 63

True

Front 64

What are the two major AE of Precose?

Back 64

Flatulence and diarrhea

Front 65

T or F

If a pt skips a meal they should not skip their dose of Precose.

Back 65

False. (if you skip a meal skip this dose too)

Front 66

If I say Ghost tab, you should think what drug?

Back 66

Metformin

Front 67

T or F

Thiazolidinedione Agents work on insulin resistance.

Back 67

True

Front 68

T or F

A class contraindication for Thiazolidinedione agents is type 2 diabetes.

Back 68

False. Type1

Front 69

Avandia and Actos should not be used in class ___ & _____ CHF.

Back 69

3 and 4

Front 70

If you have a pt taking a thiazolidinedione agent, what would be a class AE to watch out for?

Back 70

Edema/weight gain.

Front 71

T or F

A pt taking a thiazolidinedione agent as a monotherapy agent would experience hypoglycemia.

Back 71

False (key being monotherapy)

Front 72

Lab monitoring is important w/ pts taking a thiazolidinedione agent.

Back 72

Thats just a fact jack.

Front 73

What is pioglitazone's name brand?

Back 73

Actos

Front 74

What is rosiglitazone's name brand?

Back 74

Avandia

Front 75

What is the dosing of Avandia?

Back 75

4-8 mg d.

Front 76

What is the dosing of Actos?

Back 76

15-45 mg d

Front 77

T or F

Actos and Avandia can be taken w/out regards to meals.

Back 77

True

Front 78

How often should you titrate Avandia?

Back 78

every 3 months

Front 79

How often should you titrate Actos?

Back 79

Every 3 months

Front 80

Avandia and Actos have a long or short onset of action?

Back 80

Long

Front 81

When taking insulin, corticosteroids will have what effect on insulin's action?

Back 81

oppose it! (hyperglycemia)

Front 82

Insulin + alcohol will result in hyper or hypo glycemia?

Back 82

hypo

Front 83

Humalog and Novolog are considered short or long acting?

Back 83

short

Front 84

T or F

If you have split-mixed insulin, you should gently roll it to ensure the right dose is given and it's uniformly cloudy.

Back 84

True

Front 85

Heating and freezing can denature insulin and it is no longer viable after ____ days out of the fridge

Back 85

28

Front 86

Humalog mix (75/25, 50/50) generic is?

Back 86

insulin lispro/ protamine suspension

Front 87

Humalog is insulin lispro or protamine suspension?

Back 87

insulin lispro

Front 88

Humulin comes in what strength (formulations)?

Back 88

70/30 and50/50

Front 89

Humulin generic is?

Back 89

regular insulin/ isophane suspension

Front 90

Which is isophane insulin suspension and which is regular human insulin?

(answer choices Humulin N and Humulin R)

Back 90

N = isophane insulin suspension

R= regular human insulin (R for regular)

Front 91

What is insulin glargine name brand?

Back 91

Lantus

Front 92

Insulin aspart is what?

Back 92

Novolog

Front 93

What is Novolog Mix and what is the only strength it comes in?

Back 93

insulin aspart/protamine sulfate and 70/30

Front 94

Insulin detemir's name brand is?

Back 94

Levemir

Front 95

Which of these should you gently mix before administration?

Humalog, Humulin R, Novolog, Humalog Mix, Levemir

Back 95

Humalog Mix

Front 96

Which of these is usually given bid before am and pm meals?

Novolog Mix or Humalog Mix

Back 96

Both!

Front 97

Which of these has a bi-phasic peak?

Humalog mix or humalog

Back 97

Humalog mix

Front 98

You should administer Humalog ___ minutes prior to eating.

Back 98

15 min

Front 99

You should administer Humalog Mix_____ minutes prior to am and pm meal.

Back 99

15 min

Front 100

Humalog usually peaks how quickly in the body?

Back 100

w/in 90 minutes.

Front 101

Humalog is usually cleared how quickly in the body?

Back 101

w/in 4 hours

Front 102

Which has the longest duration of action out of: Humulin 70/30, Humulin N, Humulin R

Back 102

Humulin R

Front 103

Which of these is generally bid (before am and pm meals), daily or bid, and generally pre-meals.

(Humulin 70/30, Humulin N, Humulin R)

Back 103

70/30 = generally bid (am and pm meals)

R= generally pre-meals

N- daily or bid

Front 104

In Humulin 70/30, which is the long acting % and what does the other part do?

Back 104

70% = long acting and the 30% provides meal coverage

Front 105

Which insulin is not given in relation to food?

Back 105

Lantus (glargine)

Front 106

When is Lantus usually administered?

Back 106

Generally at bedtime

Front 107

Lantus is usually given once daily, but they can give it BID when?

Back 107

Only when burning upon administration due to high volume.

Front 108

T or F

Lantus can be diluted or mixed with other insulins

Back 108

FALSE FALSE GALSE

Front 109

T or F.

You should counsel a pt who's using Lantus to give it at the SAME time every day.

Back 109

True

Front 110

Which is considered a "long-acting/basal insulin"?

Back 110

Lantus and Levemir

Front 111

T or F

Novolog is more rapid acting than regular insulin.

Back 111

True

Front 112

When counseling a pt using Novolog you want to tell them to administer the drug _____ minutes prior to meal.

Back 112

10-15

Front 113

Lantus is given IM or SQ?

Back 113

SQ

Front 114

Levemir is given IM or SQ?

Back 114

SQ

Front 115

You can dose Levemir how often?

Back 115

Q12 hours

Front 116

If you have a pt who's taking Levemir once daily,you should advise them to use it when?

Back 116

PM or QHS

Front 117

T or F

You can dilute or mix Levemir with another insulin.

Back 117

FALSE GALSE FALSE GALSE

Front 118

Which of these is not like the other due to onset time?

Aspart, Glulisine (Apidra), Humulin N, Lispro

Back 118

Humulin N (2-4 hours)

The rest are 5-15 minutes

Front 119

The onset time of Regular insulin (Humulin R and Novolin R) is?

Back 119

30-60 minutes

Front 120

T or F

Novolog, Apidra, and Humalog all have the same onset, peak, usual effective duration, max duration, and usual dosing frequency.

Back 120

False. (only difference is max duration. Humalogs is 4-6 hours. The other two are 5-6 hours)

Front 121

When do you dose Novolog, Apidra, and Humalog?

Back 121

15 minutes before meals

Front 122

Which of these drugs has a peak of 1-2 hours?

Humulin R, Levemir, Novolog, or Lantus

Back 122

Novolog

Front 123

Which of these has the fastest onset?

Humulin R, Levemir, Novolog, or Lantus

Back 123

Novolog

Front 124

Which of these has the slowest onset?

Humulin R, Levemir, Novolog, or Lantus

Back 124

Lantus

Front 125

Which of these is actually Peak-less?

Humulin R, Levemir, Apidra, Lantus, or Humalog

Back 125

Lantus

Front 126

What is the max duration of Humulin R (and Novolin R)?

Back 126

6-8 hours

Front 127

Which of these has a max duration of 14-18 hours?

Apidra, Novolin R, Humulin N, or Levemir

Back 127

Humulin N

Front 128

The onset time of Levemir is?

Back 128

2 hours

Front 129

Which drug has a peak of 2-3 hours?

Back 129

Humulin R

Front 130

Which drug has a peak of 6-10 hours?

Back 130

Levemir

Front 131

You would administer which of these 30 minutes before a meal?

Humulin R, Humulin N, Levemir, Lantus, or Novolog

Back 131

Humulin R

Front 132

The max duration of Levemir is?

Back 132

24 hours

Front 133

1 cc = ___ units

Back 133

100

Front 134

Most insulin vials are how many mLs?

Back 134

10 mLs

Front 135

There are how many pens per box (and how many mL per pen)

Back 135

5 pens per box each containing 3 mL (so 15 mL per box)

Front 136

T or F.

The larger the gauge the finer the needle.

Back 136

True

Front 137

If you have a pt who is hypotensive and crashing what gauge needle do you use?

Back 137

22

Front 138

A 3/10 cc syringe will hold how much insulin?

Back 138

30 units

Front 139

A 1/2 cc syringe will hold how much insulin?

Back 139

50 units

Front 140

IBW equation?

Back 140

Males:

50 +2.3(Height in inches - 60)

Females

45.5 + 2.3 (height in inches - 60)

Front 141

Cockcroft-Gault equation?

Back 141

[(140-Age)*Wt (kg)]/ (Scr * 72)

For women multiply all that by 0.85

Front 142

When do you use ABW vs IBW?

Back 142

I still don't actually know. So ask somebody cuz I am.