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5 Cards in this Set

  • Front
  • Back

Acidic drugs

  • dantrolene
  • Dexamethasone
  • Paracetamol
  • PencilLin
  • Phenytoin
  • Propofol
  • Thiopentone
  • NSAIDs
  • Warfarin

What factors determine the effect of a drug which acts on a receptor?

  • receptor occupancy- governed by unbound drug conc and Kd and rec conc
  • Intrinsic activity
  • Intrinsic

4 types of receptors

  1. ligand gated ion channel
  2. G- prot coupled
  3. Tyrosine kinase
  4. Intracellular steroid

Mathematics affinity

Back (Definition)

What are the determinants of half life

Vd and clearance

Vd directly proportional

Clearance inversely proportional