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29 Cards in this Set
- Front
- Back
abhesive
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substance that reduces adhesion
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exectorant
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medication meant to increase the volume or hydration of airway secretions
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gel
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macromolecular description of pseudoplastic material having both viscosity and elasticity
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glycoprotein
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protein with attached oligosaccharide units
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mucin
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the principal constituent of mucus and high-molecular-weight glycoprotein, it gives mucus its physical/chemical properties such as viscoelasticity.
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mucoactive agent
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term connoting any medication or drug that has an effect on mucus secretion; may include mucolytic, expectorant, mucospissic, mucoregulatory, or mucokietic agents
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mucoregulatory agent
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drug that reduces the volume of airway mucus secretion and appears to be especially effective in hypersecretory states, such as bronchorrhea, diffuse panbronchiolitis (DPB), CF, and some forms of asthma.
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mucospissic agent
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medication that increases viscosity of secretins and may be effective in the therapy of bronchorrhea.
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mucus
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secretion, from surface goblet cells and submucosal glands, composed of water, proteins, and glycosylated mucins The glycoprotein portion of the secretion is termed mucin. Mucus (noun) is the secretion; mucous (adjective) is the cell or gland type
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oligosaccharide
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sugar that is the individual carbohydrate unit of glycoproteins
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phlegm
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purulent material in the airways. From the Greek word for inflammation. When expectorated, phlegm is called sputum
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rheology
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study of the deformation and flow of matter
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sol
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Macromolecular description of the respiratory secretion in true solution, with the physical property of viscosity (usually referred to as the periciliary layer)
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sputum
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expectorated phlegm that contains respiratory tract, oropharyngeal, and nasopharyngeal secretions and bacteria and products of inflammation including polymeric DNA and actin.
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viscosity
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resistance of liquid to sheer forces. A rheologic property characteristic of liquids and represented by the loss modulus G.
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N-Acetylcysteine
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mucomist
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mucomist
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N-Acetylcysteine
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Dornase alfa
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Pulmozyme
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Pulmozyme
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Dornase alfa
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Hyperosmolar (7%) saline
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Hyper-Sal
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dehisce
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To rupture or break open, as a surgical wound.
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diseases characterized by abnormal production of mucus
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chronic bronchitis and asthma - hypersecretion
CF - decreased secretion |
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Factors affecting mucociliary transport
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COPD / CF
Narcotics Enotracheal suctioning, airway trauma, and tracheotomy cigarette smoke atmospheric poluutants hyperoxia dn hypoxia |
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normal clearance of airway mucus can be altered by changes in
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volume
hydration composition |
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Chronic Bronchitis (CB) is defined clinically as
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daily sputum expectoration for 3 months of the year for at least 2 consecutive years.
usually a tobacco smoker or ex-tobacco smoker |
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Cystic Fibrosis (CF)
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A chronic hereditary disease characterized by impaired function of the CFTR protein.
There is chronic airway infection, often with Pseudomonas and other gram-negative organisms |
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mucolytic agents decrease the elasticity and viscosity of mucus by
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breaking down the gel structure
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physical properties of mucus include
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viscosity
elasticity cohesivity adhsivity |
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bland aerosols
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wetting agents
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